Author results

2PWA
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CRYSTAL STRUCTURE OF THE COMPLEX OF PROTEINASE K WITH ALANINE BORONIC ACID AT 0.83A RESOLUTION
Descriptor:Proteinase K, CALCIUM ION, NITRATE ION, ...
Authors:Jain, R., Singh, N., Perbandt, M., Betzel, C., Sharma, S., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2007-05-11
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.83 Å)
Cite:Crystal structure of the complex of Proteinase K with Alanine Boronic Acid at 0.83A Resolution
To be Published
4BVM
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THE PERIPHERAL MEMBRANE PROTEIN P2 FROM HUMAN MYELIN AT ATOMIC RESOLUTION
Descriptor:MYELIN P2 PROTEIN, PALMITIC ACID, VACCENIC ACID, ...
Authors:Ruskamo, S., Yadav, R.P., Kursula, P.
Deposit date:2013-06-26
Release date:2014-01-15
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Atomic Resolution View Into the Structure-Function Relationships of the Human Myelin Peripheral Membrane Protein P2
Acta Crystallogr.,Sect.D, 70, 2014
6J93
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM ACINETOBACTER BAUMANNII AT 0.95 A RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase, 1,2-ETHANEDIOL
Authors:Viswanathan, V., Sharma, P., Singh, P.K., Iqbal, N., Sharma, S., Singh, T.P.
Deposit date:2019-01-21
Release date:2019-02-06
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Crystal structure of Peptidyl-tRNA hydrolase form apo at 0.95 A resolution.
To Be Published
6JJ1
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM ACINETOBACTER BAUMANNII AT 0.97 A RESOLUTION WITH DISORDERED FIVE N-TERMINAL RESIDUES
Descriptor:Peptidyl-tRNA hydrolase, CHLORIDE ION, 1,2-ETHANEDIOL
Authors:Iqbal, N., Sharma, P., Chaudhary, A., Sharma, S., Singh, T.P.
Deposit date:2019-02-24
Release date:2019-03-13
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.97 A resolution with disordered five N-terminal residues
To Be Published
2G58
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CRYSTAL STRUCTURE OF A COMPLEX OF PHOSPHOLIPASE A2 WITH A DESIGNED PEPTIDE INHIBITOR DEHYDRO-ILE-ALA-ARG-SER AT 0.98 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, (PHQ)IARS, SULFATE ION
Authors:Prem Kumar, R., Singh, N., Somvanshi, R.K., Ethayathulla, A.S., Dey, S., Sharma, S., Kaur, P., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2006-02-22
Release date:2006-03-28
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Crystal structure of a complex of phospholipase A2 with a designed peptide inhibitor Dehydro-Ile-Ala-Arg-Ser at 0.98 A resolution
To be Published
6JJQ
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM ACINETOBACTER BAUMANNII AT 0.99 A RESOLUTION.
Descriptor:Peptidyl-tRNA hydrolase, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ...
Authors:Viswanathan, V., Bairagya, H.R., Sharma, P., Sharma, S., Singh, T.P.
Deposit date:2019-02-26
Release date:2019-03-06
Method:X-RAY DIFFRACTION (0.99 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase from Acinetobacter baumannii at 0.99 A resolution.
To Be Published
6JGU
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CRYSTAL STRUCTURE AT ATOMIC RESOLUTION REVEALS THE CATALYTIC MECHANISM IN PEPTIDYL-TRNA HYDROLASE FROM ACINETOBACTER BAUMANNII.
Descriptor:Peptidyl-tRNA hydrolase
Authors:Viswanathan, V., Sharma, P., Sharma, S., Singh, T.P.
Deposit date:2019-02-14
Release date:2019-03-06
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Crystal structure at atomic resolution reveals the catalytic mechanism in peptidyl-tRNA hydrolase from Acinetobacter baumannii.
To Be Published
6JKX
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE WITH MULTIPLE SODIUM AND CHLORIDE IONS AT 1.08 A RESOLUTION.
Descriptor:Peptidyl-tRNA hydrolase, CHLORIDE ION, METHANOL, ...
Authors:Viswanathan, V., Sharma, P., Bhushan, A., Sharma, S., Singh, T.P.
Deposit date:2019-03-03
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal structure of peptidyl-tRNA hydrolase with multiple sodium and chloride ions at 1.08 A resolution.
To Be Published
4QMC
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CRYSTAL STRUCTURE OF COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND BIOTIN-SULFOXIDE AT 1.09 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, GLYCEROL, BIOTIN-D-SULFOXIDE, ...
Authors:Shukla, P.K., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2014-06-16
Release date:2014-07-30
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Crystal structure of complex formed between phospholipase A2 and Biotin-sulfoxide at 1.09 A Resolution
To be published
1TJ9
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STRUCTURE OF THE COMPLEXED FORMED BETWEEN GROUP II PHOSPHOLIPASE A2 AND A RATIONALLY DESIGNED TETRA PEPTIDE,VAL-ALA-ARG-SER AT 1.1A RESOLUTION
Descriptor:Phospholipase A2, VARS peptide, SULFATE ION, ...
Authors:Singh, N., Ethayathulla, A.S., K Somvanshi, R., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Kaur, P., Singh, T.P.
Deposit date:2004-06-03
Release date:2004-06-08
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of the complex formed between group II phospholipase A2 and a rationally designed tetra peptide,Val-Ala-Arg-Ser at 1.1A resolution
TO BE PUBLISHED
1TK4
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CRYSTAL STRUCTURE OF RUSSELLS VIPER PHOSPHOLIPASE A2 IN COMPLEX WITH A SPECIFICALLY DESIGNED TETRAPEPTIDE ALA-ILE-ARG-SER AT 1.1 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, Tetrapeptide Ala-Ile-Arg-Ser, SULFATE ION
Authors:Singh, N., Bilgrami, S., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Kaur, P., Singh, T.P.
Deposit date:2004-06-08
Release date:2004-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of russells viper phospholipase A2 with a specifically designed tetrapeptide Ala-Ile-Arg-Ser at 1.1 A resolution
TO BE PUBLISHED
1ZWP
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THE ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE PHOSPHOLIPASE A2 (PLA2) COMPLEX WITH NIMESULIDE REVEALS ITS WEAKER BINDING TO PLA2
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, ...
Authors:Prem Kumar, R., Singh, N., Sharma, S., Kaur, P., Singh, T.P.
Deposit date:2005-06-04
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The atomic resolution Crystal structure of the Phospholipase A2 (PLA2) complex with Nimesulide reveals its weaker binding to PLA2
To be Published
5Y9A
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CRYSTAL STRUCTURE OF THE COMPLEX OF PEPTIDYL TRNA HYDROLASE WITH A PHOSPHATE ION AT THE SUBSTRATE BINDING SITE AND CYTARABINE AT A NEW LIGAND BINDING SITE AT 1.1 A RESOLUTION
Descriptor:Peptidyl-tRNA hydrolase, CYTARABINE, PHOSPHATE ION
Authors:Kaushik, S., Iqbal, N., Singh, N., Singh, P.K., Sharma, S., Singh, T.P.
Deposit date:2017-08-23
Release date:2017-09-13
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Search of multiple hot spots on the surface of peptidyl-tRNA hydrolase: structural, binding and antibacterial studies.
Biochem. J., 475, 2018
1SQZ
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DESIGN OF SPECIFIC INHIBITORS OF PHOPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GROUP II PHOPHOLIPASE A2 AND A DESIGNED PEPTIDE DEHYDRO-ILE-ALA-ARG-SER AT 1.2A RESOLUTION
Descriptor:Phospholipase A2, synthetic peptide, SULFATE ION
Authors:Singh, N., Prem Kumar, R., Somvanshi, R.K., Bilgrami, S., Ethayathulla, A.S., Sharma, S., Dey, S., Singh, T.P.
Deposit date:2004-03-22
Release date:2004-04-13
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Design of specific inhibitors of Phopholipase A2: Crystal structure of the complex formed between GroupII Phopholipase A2 and a designed peptide Dehydro-Ile-Ala-Arg-Ser at 1.2A resolution
To be Published
2OYF
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CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH INDOLE ACETIC ACID AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 1H-INDOL-3-YLACETIC ACID, ...
Authors:Kumar, S., Hariprasad, G., Singh, N., Sharma, S., Kaur, P., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2007-02-22
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structure of the complex of phospholipase A2 with indole acetic acid at 1.2 A resolution
To be Published
3JQL
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND A HEXAPEPTIDE FRAGMENT OF AMYLOID BETA PEPTIDE, LYS-LEU-VAL-PHE-PHE-ALA AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 isoform 3, Amyloid Beta Peptide, CALCIUM ION
Authors:Mirza, Z., Vikram, G., Singh, N., Sinha, M., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P.
Deposit date:2009-09-07
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyloid Beta Peptide, Lys-Leu-Val-Phe-Phe-Ala at 1.2 A Resolution
To be Published
4QEM
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CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH P-COUMARIC ACID AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 4'-HYDROXYCINNAMIC ACID
Authors:Shukla, P.K., Tiwari, P., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2014-05-17
Release date:2014-06-18
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structures and binding studies of the complexes of phospholipase A2 with five inhibitors
Biochim.Biophys.Acta, 1854, 2015
4QER
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CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH RESVERATROL AT 1.20 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, RESVERATROL
Authors:Shukla, P.K., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2014-05-18
Release date:2014-06-18
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structures and binding studies of the complexes of phospholipase A2 with five inhibitors
Biochim.Biophys.Acta, 1854, 2015
1SKG
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STRUCTURE-BASED RATIONAL DRUG DESIGN: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND A PENTAPEPTIDE VAL-ALA-PHE-ARG-SER
Descriptor:Phospholipase A2, VAFRS, SULFATE ION, ...
Authors:Ethayathulla, A.S., Singh, N., Sharma, S., Makker, J., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-03-04
Release date:2004-04-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structure-based rational drug design: Crystal structure of the complex formed between Phospholipase A2 and a pentapeptide Val-Ala-Phe-Arg-Ser
To be Published
1SXK
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND A NON-SPECIFIC ANTI-INFLAMMATORY AMINO SALICYLIC ACID AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 2-HYDROXY-4-AMINOBENZOIC ACID
Authors:Singh, N., Bilgrami, S., Kaur, P., Sharma, S., Singh, T.P.
Deposit date:2004-03-31
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal Structure of a complex formed between phospholipase A2 and a non-specific anti-inflammatory amino salicylic acid at 1.2 A resolution
To be Published
1TH6
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CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 IN COMPLEX WITH ATROPINE AT 1.23A RESOLUTION
Descriptor:Phospholipase A2, (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, SULFATE ION
Authors:Singh, N., Pal, A., Jabeen, T., Sharma, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-06-01
Release date:2004-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structure of phospholipase A2 in complex with atropine at 1.23A resolution
To be Published
2ARM
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CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH A NATURAL COMPOUND ATROPINE AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, SULFATE ION
Authors:Singh, N., Pal, A., Jabeen, T., Sharma, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2005-08-20
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
1TG1
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN RUSSELLS VIPER PHOSPHOLIPASE A2 AND A DESIGNED PEPTIDE INHIBITOR PHQ-LEU-VAL-ARG-TYR AT 1.2A RESOLUTION
Descriptor:Phospholipase A2, peptide inhibitor, SULFATE ION, ...
Authors:Singh, N., Kaur, P., Somvanshi, R.K., Sharma, S., Dey, S., Perbandt, M., Betzel, C., Singh, T.P.
Deposit date:2004-05-28
Release date:2004-06-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the complex formed between russells viper phospholipase A2 and a designed peptide inhibitor Cbz-dehydro-Leu-Val-Arg-Tyr at 1.2A resolution
To be Published
1TJK
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN GROUP II PHOSPHOLIPASE A2 WITH A DESIGNED PENTAPEPTIDE, PHE- LEU- SER- THR- LYS AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2, synthetic peptide, SULFATE ION
Authors:Singh, N., Jabeen, T., Somvanshi, R.K., Sharma, S., Perbandt, M., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2004-06-06
Release date:2004-06-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe - Leu - Ser - Thr - Lys at 1.2 A resolution
To be Published
3G8F
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN A GROUP II PHOSPHOLIPASE A2 AND DESIGNED PEPTIDE INHIBITOR CARBOBENZOXY-DEHYDRO-VAL-ALA-ARG-SER AT 1.2 A RESOLUTION
Descriptor:Phospholipase A2 VRV-PL-VIIIa, PHQ VAL ALA ARG SER peptide, SULFATE ION
Authors:Singh, N., Kaur, P., Prem Kumar, R., Somvanshi, R.K., Perbandt, M., Betzel, C., Dey, S., Sharma, S., Singh, T.P.
Deposit date:2009-02-12
Release date:2009-03-10
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal Structure of the Complex Formed between a Group II Phospholipase A2 and Designed Peptide Inhibitor Carbobenzoxy-Dehydro-Val-Ala-Arg-Ser at 1.2 A Resolution
To be Published