Author results

1XPV
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SOLUTION STRUCTURE OF NORTHEAST STRUCTURAL GENOMICS TARGET PROTEIN XCR50 FROM X. CAMPESTRIS
分子名称:hypothetical protein XCC2852
著者Shao, Y., Acton, T.B., Liu, G., Ma, L., Shen, Y., Xiao, R., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2004-10-09
公開日2004-12-14
最終更新日2018-01-31
実験手法SOLUTION NMR
主引用文献Solution Structure of Northeast Structural Genomics Target Protein XcR50 from X. Campestris
To be Published
4H4K
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STRUCTURE OF THE CMR2-CMR3 SUBCOMPLEX OF THE CMR RNA-SILENCING COMPLEX
分子名称:CRISPR system Cmr subunit Cmr3, CRISPR system Cmr subunit Cmr2, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shao, Y., Cocozaki, A.I., Ramia, N.F., Terns, R.M., Terns, M.P., Li, H.
登録日2012-09-17
公開日2013-03-06
最終更新日2016-03-30
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structure of the cmr2-cmr3 subcomplex of the cmr RNA silencing complex.
Structure, 21, 2013
4ILL
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RECOGNITION AND CLEAVAGE OF A NON-STRUCTURED CRISPR RNA BY ITS PROCESSING ENDORIBONUCLEASE CAS6
分子名称:CRISPR-associated endoribonuclease Cas6 2, RNA (5'-R(*GP*CP*UP*AP*AP*UP*CP*UP*AP*CP*UP*AP*UP*AP*GP*AP*AP*UP*UP*GP*AP*AP*AP*G)-3')
著者Shao, Y., Li, H.
登録日2012-12-31
公開日2013-03-20
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.
Structure, 21, 2013
4ILM
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CRISPR RNA PROCESSING ENDORIBONUCLEASE
分子名称:CRISPR-associated endoribonuclease Cas6 2, RNA (5'-R(*GP*CP*UP*AP*AP*UP*CP*UP*AP*CP*UP*AP*UP*AP*GP*A)-3')
著者Shao, Y., Li, H.
登録日2012-12-31
公開日2013-03-20
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (3.068 Å)
主引用文献Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.
Structure, 21, 2013
4ILR
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RECOGNITION AND CLEAVAGE OF A NON-STRUCTURED CRISPR RNA BY ITS PROCESSING ENDORIBONUCLEASE CAS6
分子名称:CRISPR-associated endoribonuclease Cas6 2
著者Shao, Y., Li, H.
登録日2012-12-31
公開日2013-03-20
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (3.088 Å)
主引用文献Recognition and cleavage of a nonstructured CRISPR RNA by its processing endoribonuclease Cas6.
Structure, 21, 2013
4RDP
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CRYSTAL STRUCTURE OF CMR4
分子名称:CRISPR system Cmr subunit Cmr4
著者Shao, Y., Tang, L., Li, H.
登録日2014-09-19
公開日2014-12-24
最終更新日2014-12-31
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Essential Structural and Functional Roles of the Cmr4 Subunit in RNA Cleavage by the Cmr CRISPR-Cas Complex.
Cell Rep, 9, 2014
5E08
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SPECIFIC RECOGNITION OF A SINGLE-STRANDED RNA SEQUENCE BY AN ENGINEERED SYNTHETIC ANTIBODY FRAGMENT
分子名称:Fab Heavy Chain, Fab Light Chain, RNA
著者Huang, H., Qin, D., Li, N., Shao, Y., Staley, J.P., Kossiakoff, A.A., Koide, S., Piccirilli, J.A.
登録日2015-09-28
公開日2016-09-21
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
6DB8
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STRUCTURAL BASIS FOR PROMISCUOUS BINDING AND ACTIVATION OF FLUOROGENIC DYES BY DIR2S RNA APTAMER
分子名称:Fab-Heavy chain, RNA (60-MER), Fab-Light chain, ...
著者Shao, Y., Shelke, S.A., Laski, A., Piccirilli, J.A.
登録日2018-05-02
公開日2018-11-14
実験手法X-RAY DIFFRACTION (1.865413 Å)
主引用文献Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
6DB9
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STRUCTURAL BASIS FOR PROMISCUOUS BINDING AND ACTIVATION OF FLUOROGENIC DYES BY DIR2S RNA APTAMER
分子名称:RNA (60-MER), Fab-Heavy-Chain, Fab-Light-Chain, ...
著者Shao, Y., Shelke, S.A., Laski, A., Piccirilli, J.A.
登録日2018-05-02
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2.025 Å)
主引用文献Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
1J48
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CRYSTAL STRUCTURE OF APO-C1027
分子名称:Apoprotein of C1027
著者Chen, Y., Li, J., Liu, Y., Bartlam, M., Gao, Y., Jin, L., Tang, H., Shao, Y., Zhen, Y., Rao, Z.
登録日2001-07-30
公開日2003-06-03
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
1LV0
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CRYSTAL STRUCTURE OF THE RAB EFFECTOR GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR (GDI) IN COMPLEX WITH A GERANYLGERANYL (GG) PEPTIDE
分子名称:RAB GDP disossociation inhibitor alpha, SULFATE ION, GERAN-8-YL GERAN
著者An, Y., Shao, Y., Alory, C., Matteson, J., Sakisaka, T., Chen, W., Gibbs, R.A., Wilson, I.A., Balch, W.E.
登録日2002-05-23
公開日2003-08-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Geranylgeranyl switching regulates GDI-Rab GTPase recycling.
Structure, 11, 2003
6MWN
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CRYSTAL STRUCTURE OF HEPATITIS A VIRUS IRES DOMAIN V IN COMPLEX WITH FAB HAVX
分子名称:HAV dV RNA (92-MER), Fab HAVx Heavy Chain, Fab HAVx Light Chain
著者Koirala, D., Shao, Y., Piccirilli, J.A.
登録日2018-10-29
公開日2019-08-14
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.838 Å)
主引用文献A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Nat Commun, 10, 2019
1MC7
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SOLUTION STRUCTURE OF MDVL1 PDZ DOMAIN
分子名称:Segment polarity protein dishevelled homolog DVL-1
著者Wong, H.-C., Bourdelas, A., Shao, Y., Wu, D., Shi, D.L., Zheng, J.
登録日2002-08-05
公開日2003-09-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
Mol.Cell, 12, 2003
1TUZ
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NMR STRUCTURE OF THE DIACYLGLYCEROL KINASE ALPHA, NESGC TARGET HR532
分子名称:diacylglycerol kinase alpha
著者Liu, G., Shao, Y., Xiao, R., Acton, T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
登録日2004-06-25
公開日2005-01-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of Diacylglycerol kinase alpha, NESGC target HR532
To be Published
2JTK
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A FUNCTIONAL DOMAIN OF A WNT SIGNAL PROTEIN
分子名称:Dickkopf-related protein 2
著者Chen, L., Shao, Y., Huang, J., Zheng, J.
登録日2007-08-02
公開日2008-07-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the mechanisms of wnt signaling antagonism by dkk
J.Biol.Chem., 283, 2008
3UNG
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STRUCTURE OF THE CMR2 SUBUNIT OF THE CRISPR RNA SILENCING COMPLEX
分子名称:Cmr2dHD, CALCIUM ION, ZINC ION, ...
著者Cocozaki, A.I., Ramia, N.F., Shao, Y., Hale, C.R., Terns, R.M., Terns, M.P., Li, H.
登録日2011-11-15
公開日2012-03-21
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex.
Structure, 20, 2012
3UR3
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STRUCTURE OF THE CMR2 SUBUNIT OF THE CRISPR RNA SILENCING COMPLEX
分子名称:Cmr2dHD, CALCIUM ION, ZINC ION
著者Cocozaki, A.I., Ramia, N.F., Shao, Y., Hale, C.R., Terns, R.M., Terns, M.P., Li, H.
登録日2011-11-21
公開日2012-03-21
最終更新日2015-02-04
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex.
Structure, 20, 2012
3WFV
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HIV-1 CRF07 GP41
分子名称:Envelope glycoprotein gp160
著者Du, J., Xue, H., Ma, J., Liu, F., Zhou, J., Shao, Y., Qiao, W., Liu, X.
登録日2013-07-24
公開日2013-10-16
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of HIV CRF07 B'/C gp41 reveals a hyper-mutant site in the middle of HR2 heptad repeat
Virology, 446, 2013
5C7U
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5'-MONOPHOSPHATE WT GUANINE RIBOSWITCH BOUND TO HYPOXANTHINE.
分子名称:5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A., Benner, S.A.
登録日2015-06-24
公開日2015-08-12
最終更新日2015-08-19
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
5C7W
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5'-MONOPHOSPHATE Z:P GUANINE RIBOSWITCH BOUND TO HYPOXANTHINE.
分子名称:5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R., Shao, Y., Hoshika, S., Yang, Z., Shelke, S.A., Herrou, J., Kim, H.-J., Kim, M.-J., Piccirilli, J.A., Benner, S.A.
登録日2015-06-25
公開日2015-08-12
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Z7K
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CRYSTAL STRUCTURE OF CRISPR RNA PROCESSING ENDORIBONUCLEASE CAS6B
分子名称:Cas6b, RNA/DNA Hybrid (31-MER)
著者Li, H.
登録日2015-04-07
公開日2016-04-13
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Structure, 24, 2016
4Z7L
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CRYSTAL STRUCTURE OF CAS6B
分子名称:Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION
著者Li, H.
登録日2015-04-07
公開日2016-04-13
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6.
Structure, 24, 2016
4MD6
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CRYSTAL STRUCTURE OF PDE5 IN COMPLEX WITH INHIBITOR 5R
分子名称:cGMP-specific 3',5'-cyclic phosphodiesterase, SULFATE ION, 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one, ...
著者Cui, W., Huang, M., Shao, Y., Luo, H.
登録日2013-08-22
公開日2014-07-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one as a phosphodiesterase-5 inhibitor and its complex crystal structure.
Biochem Pharmacol, 89, 2014
5CD3
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STRUCTURE OF IMMATURE VRC01-CLASS ANTIBODY DRVIA7
分子名称:DRVIA7 Heavy Chain, DRVIA7 Light Chain
著者Kong, L., Wilson, I.A.
登録日2015-07-02
公開日2016-04-06
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
5CD5
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CRYSTAL STRUCTURE OF AN IMMATURE VRC01-CLASS ANTIBODY DRVIA7 FROM A CHINESE DONOR BOUND TO CLADE A/E HIV-1 GP120 CORE
分子名称:93TH057 HIV-1 gp120 core, DRVIA7 Fab Heavy Chain, DRVIA7 Fab Light Chain, ...
著者Kong, L., Wilson, I.A.
登録日2015-07-03
公開日2016-04-06
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (3.396 Å)
主引用文献Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.
Immunity, 44, 2016
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