Author results

1YR2
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STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY
Descriptor:prolyl oligopeptidase, GLYCEROL
Authors:Shan, L., Mathews, I.I., Khosla, C.
Deposit date:2005-02-02
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity
Proc.Natl.Acad.Sci.USA, 102, 2005
1U9M
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CRYSTAL STRUCTURE OF F58W MUTANT OF CYTOCHROME B5
Descriptor:Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shan, L., Lu, J.-X., Gan, J.-H., Wang, Y.-H., Huang, Z.-X., Xia, Z.-X.
Deposit date:2004-08-10
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions.
Acta Crystallogr.,Sect.D, 61, 2005
1U9U
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CRYSTAL STRUCTURE OF F58Y MUTANT OF CYTOCHROME B5
Descriptor:Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Shan, L., Lu, J.-X., Gan, J.-H., Wang, Y.-H., Huang, Z.-X., Xia, Z.-X.
Deposit date:2004-08-11
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of the F58W mutant of cytochrome b5: the mutation leads to multiple conformations and weakens stacking interactions.
Acta Crystallogr.,Sect.D, 61, 2005
2PQE
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SOLUTION STRUCTURE OF PROLINE-FREE MUTANT OF STAPHYLOCOCCAL NUCLEASE
Descriptor:Thermonuclease
Authors:Shan, L., Tong, Y., Xie, T., Wang, M., Wang, J.
Deposit date:2007-05-01
Release date:2007-06-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.
Biochemistry, 46, 2007
2BKL
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STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY
Descriptor:PROLYL ENDOPEPTIDASE, N-[(BENZYLOXY)CARBONYL]-L-ALANYL-L-PROLINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Khosla, C., Shan, L., Mathews, I.I.
Deposit date:2005-02-16
Release date:2005-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity
Proc.Natl.Acad.Sci.USA, 102, 2005
5HVW
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MONOMERIC IGG4 FC
Descriptor:Ig gamma-4 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Oganesyan, V.Y., Shan, L., Dall'Acqua, W.F.
Deposit date:2016-01-28
Release date:2016-08-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Generation and Characterization of an IgG4 Monomeric Fc Platform.
Plos One, 11, 2016
1ETZ
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THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS
Descriptor:FAB NC10.14 - LIGHT CHAIN, FAB NC10.14 - HEAVY CHAIN, N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID
Authors:Guddat, L.W., Shan, L., Broomell, C., Ramsland, P.A., Fan, Z., Anchin, J.M., Linthicum, D.S., Edmundson, A.B.
Deposit date:2000-04-13
Release date:2000-10-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
J.Mol.Biol., 302, 2000
1B2W
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COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor:PROTEIN (ANTIBODY (LIGHT CHAIN)), PROTEIN (ANTIBODY (HEAVY CHAIN))
Authors:Fan, Z., Shan, L., Goldsteen, B.Z., Guddat, L.W., Thakur, A., Landolfi, N.F., Co, M.S., Vasquez, M., Queen, C., Ramsland, P.A., Edmundson, A.B.
Deposit date:1998-12-01
Release date:1999-05-06
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1B4J
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COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
Descriptor:ANTIBODY
Authors:Fan, Z., Shan, L., Goldsteen, B.Z., Guddat, L.W., Thakur, A., Landolfi, N.F., Co, M.S., Vasques, M., Queen, C., Ramsland, P.A., Edmundson, A.B.
Deposit date:1998-12-22
Release date:1999-06-15
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
1CGS
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LOCAL AND TRANSMITTED CONFORMATIONAL CHANGES ON COMPLEXATION OF AN ANTI-SWEETENER FAB
Descriptor:IGG2B-KAPPA NC6.8 FAB (LIGHT CHAIN), IGG2B-KAPPA NC6.8 FAB (HEAVY CHAIN)
Authors:Guddat, L.W., Shan, L., Edmundson, A.B.
Deposit date:1993-10-06
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Local and transmitted conformational changes on complexation of an anti-sweetener Fab.
J.Mol.Biol., 236, 1994
1DQL
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CRYSTAL STRUCTURE OF AN UNLIGANDED (NATIVE) FV FROM A HUMAN IGM ANTI-PEPTIDE ANTIBODY
Descriptor:IGM MEZ IMMUNOGLOBULIN
Authors:Ramsland, P.A., Shan, L., Moomaw, C.R., Slaughter, C.A., Guddat, L.W., Edmundson, A.B.
Deposit date:2000-01-04
Release date:2000-10-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An unusual human IgM antibody with a protruding HCDR3 and high avidity for its peptide ligands.
Mol.Immunol., 37, 2000
1JVK
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THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR
Descriptor:IMMUNOGLOBULIN LAMBDA LIGHT CHAIN
Authors:Bourne, P.C., Ramsland, P.A., Shan, L., Fan, Z.-C., DeWitt, C.R., Shultz, B.B., Terzyan, S.S., Edmundson, A.B.
Deposit date:2001-08-30
Release date:2002-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties.
Acta Crystallogr.,Sect.D, 58, 2002
1NOT
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THE 1.2 ANGSTROM STRUCTURE OF G1 ALPHA CONOTOXIN
Descriptor:GI ALPHA CONOTOXIN
Authors:Guddat, L.W., Shan, L., Martin, J.L., Edmundson, A.B., Gray, W.R.
Deposit date:1996-05-02
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Three-dimensional structure of the alpha-conotoxin GI at 1.2 A resolution
Biochemistry, 35, 1996
1RKN
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SOLUTION STRUCTURE OF 1-110 FRAGMENT OF STAPHYLOCOCCAL NUCLEASE WITH G88W MUTATION
Descriptor:Thermonuclease
Authors:Liu, D.S., Feng, Y.G., Ye, K.Q., Shan, L., Wang, J.F.
Deposit date:2003-11-22
Release date:2004-12-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2CGR
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LOCAL AND TRANSMITTED CONFORMATIONAL CHANGES ON COMPLEXATION OF AN ANTI-SWEETENER FAB
Descriptor:IGG2B-KAPPA NC6.8 FAB (LIGHT CHAIN), IGG2B-KAPPA NC6.8 FAB (HEAVY CHAIN), N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID
Authors:Guddat, L.W., Shan, L., Edmundson, A.B.
Deposit date:1993-11-23
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Local and transmitted conformational changes on complexation of an anti-sweetener Fab.
J.Mol.Biol., 236, 1994
2F3V
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SOLUTION STRUCTURE OF 1-110 FRAGMENT OF STAPHYLOCOCCAL NUCLEASE WITH V66W MUTATION
Descriptor:Thermonuclease
Authors:Liu, D., Xie, T., Feng, Y., Shan, L., Ye, K., Wang, J.
Deposit date:2005-11-22
Release date:2006-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2F3W
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SOLUTION STRUCTURE OF 1-110 FRAGMENT OF STAPHYLOCOCCAL NUCLEASE IN 2M TMAO
Descriptor:Thermonuclease
Authors:Liu, D., Xie, T., Feng, Y., Shan, L., Ye, K., Wang, J.
Deposit date:2005-11-22
Release date:2006-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2FXY
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SOLUTION STRUCTURE OF 55-72 SEGMENT OF STAPHYLOCOCCAL NUCLEASE
Descriptor:18-mer peptide from Thermonuclease
Authors:Wang, M., Shan, L., Wang, J.F.
Deposit date:2006-02-07
Release date:2006-12-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2FXZ
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SOLUTION STRUCTURE OF 97-109 SEGMENT OF STAPHYLOCOCCAL NUCLEASE
Descriptor:13-mer peptide from Thermonuclease
Authors:Wang, M., Shan, L., Wang, J.F.
Deposit date:2006-02-07
Release date:2006-12-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2KHS
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SOLUTION STRUCTURE OF SNASE121:SNASE(111-143) COMPLEX
Descriptor:Thermonuclease, Nuclease
Authors:Geng, Y., Feng, Y., Xie, T., Shan, L., Wang, J.
Deposit date:2009-04-10
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The native-like interactions between SNase121 and SNase(111-143) fragments induce the recovery of their native-like structures and the ability to degrade DNA.
Biochemistry, 48, 2009
2M00
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SOLUTION STRUCTURE OF STAPHYLOCOCCAL NUCLEASE E43S MUTANT IN THE PRESENCE OF SSDNA AND CD2+
Descriptor:Thermonuclease
Authors:Xie, T., Feng, Y., Shan, L., Wang, J.
Deposit date:2012-10-14
Release date:2013-03-06
Last modified:2013-04-03
Method:SOLUTION NMR
Cite:Modeling of the [E43S]SNase-ssDNA-Cd(2+) complex: Structural insight into the action of nuclease on ssDNA.
Arch.Biochem.Biophys., 532, 2013
6BIT
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SIRPALPHA ANTIBODY COMPLEX
Descriptor:KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Ring, N.G., Herndler-Brandstetter, D., Weiskopf, K., Shan, L., Volkmer, J.P., George, B.M., Lietzenmayer, M., McKenna, K.M., Naik, T.J., McCarty, A., Zheng, Y., Ring, A.M., Flavell, R.A., Weissman, I.L.
Deposit date:2017-11-03
Release date:2017-12-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1XNX
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CRYSTAL STRUCTURE OF CONSTITUTIVE ANDROSTANE RECEPTOR
Descriptor:constitutive androstane receptor, 16,17-ANDROSTENE-3-OL
Authors:Fernandez, E.
Deposit date:2004-10-05
Release date:2005-01-04
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the murine constitutive androstane receptor complexed to androstenol; a molecular basis for inverse agonism
Mol.Cell, 16, 2004
1Y9X
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SOLUTION STRUCTURE OF ARCHAEON DNA-BINDING PROTEIN SSH10B
Descriptor:DNA/RNA-binding protein Alba 1
Authors:Cui, Q., Tong, Y., Wang, J.
Deposit date:2004-12-16
Release date:2005-06-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A stabilizing alpha/beta-hydrophobic core greatly contributes to hyperthermostability of archaeal [P62A]Ssh10b.
Biochemistry, 47, 2008
1AQK
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THREE-DIMENSIONAL STRUCTURE OF A HUMAN FAB WITH HIGH AFFINITY FOR TETANUS TOXOID
Descriptor:FAB B7-15A2
Authors:Faber, C., Fan, Z., Edmundson, A.B.
Deposit date:1997-07-30
Release date:1998-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Three-dimensional structure of a human Fab with high affinity for tetanus toxoid.
Immunotechnology, 3, 1998
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