Author results

3SN6
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CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX
Descriptor:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Rasmussen, S.G.F., DeVree, B.T., Zou, Y., Kruse, A.C., Chung, K.Y., Kobilka, T.S., Thian, F.S., Chae, P.S., Pardon, E., Calinski, D., Mathiesen, J.M., Shah, S.T.A., Lyons, J.A., Caffrey, M., Gellman, S.H., Steyaert, J., Skiniotis, G., Weis, W.I., Sunahara, R.K., Kobilka, B.K.
Deposit date:2011-06-28
Release date:2011-07-20
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011
4D2B
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STRUCTURE OF A LIGAND FREE POT FAMILY PEPTIDE TRANSPORTER
Descriptor:DI-OR TRIPEPTIDE\:H+ SYMPORTER, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2C
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STRUCTURE OF A DI PEPTIDE BOUND POT FAMILY PEPTIDE TRANSPORTER
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2D
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STRUCTURE OF A TRI PEPTIDE BOUND POT FAMILY PEPTIDE TRANSPORTER
Descriptor:DI-OR TRIPEPTIDE\:H+ SYMPORTER, ALANINE-TRIPEPTIDE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Lyons, J.A., Parker, J.L., Solcan, N., Brinth, A., Li, D., Shah, S.T.A., Caffrey, M., Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4NC3
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CRYSTAL STRUCTURE OF THE 5-HT2B RECEPTOR SOLVED USING SERIAL FEMTOSECOND CRYSTALLOGRAPHY IN LIPIDIC CUBIC PHASE.
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 2B and E. Coli soluble cytochrome b562, PALMITIC ACID, Ergotamine, ...
Authors:Liu, W., Wacker, D., Gati, C., Han, G.W., James, D., Wang, D., Nelson, G., Weierstall, U., Katritch, V., Barty, A., Zatsepin, N.A., Li, D., Messerschmidt, M., Boutet, S., Williams, G.J., Koglin, J.E., Seibert, M.M., Wang, C., Shah, S.T.A., Basu, S., Fromme, R., Kupitz, C., Rendek, K.N., Grotjohann, I., Fromme, P., Kirian, R.A., Beyerlein, K.R., White, T.A., Chapman, H.N., Caffrey, M., Spence, J.C.H., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Serial femtosecond crystallography of G protein-coupled receptors.
Science, 342, 2013
4O9R
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HUMAN SMOOTHENED RECEPTOR STRUCTURE IN COMPLEX WITH CYCLOPAMINE
Descriptor:Smoothened homolog/Soluble cytochrome b562 chimeric protein, Cyclopamine
Authors:Wang, C., Weierstall, U., James, D., White, T.A., Wang, D., Liu, W., Spence, J.C.H., Doak, R.B., Nelson, G., Fromme, P., Fromme, R., Grotjohann, I., Kupitz, C., Zatsepin, N.A., Liu, H., Basu, S., Wacker, D., Han, G.W., Katritch, V., Boutet, S., Messerschmidt, M., Willams, G.J., Koglin, J.E., Seibert, M.M., Klinker, M., Gati, C., Shoeman, R.L., Barty, A., Chapman, H.N., Kirian, R.A., Beyerlein, K.R., Stevens, R.C., Li, D., Shah, S.T.A., Howe, N., Caffrey, M., Cherezov, V., GPCR Network (GPCR)
Deposit date:2014-01-02
Release date:2014-03-05
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.
Nat Commun, 5, 2014
4U9L
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STRUCTURE OF A MEMBRANE PROTEIN
Descriptor:Magnesium transporter MgtE, MAGNESIUM ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Takeda, H., Hattori, M., Nishizawa, T., Yamashita, K., Shah, S.T.A., Caffrey, M., Maturana, A.D., Ishitani, R., Nureki, O.
Deposit date:2014-08-06
Release date:2014-12-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
4U9N
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STRUCTURE OF A MEMBRANE PROTEIN
Descriptor:Magnesium transporter MgtE, MANGANESE (II) ION, OLEIC ACID, ...
Authors:Takeda, H., Hattori, M., Nishizawa, T., Yamashita, K., Shah, S.T.A., Caffrey, M., Maturana, A.D., Ishitani, R., Nureki, O.
Deposit date:2014-08-06
Release date:2014-12-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
4WIB
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CRYSTAL STRUCTURE OF MAGNESIUM TRANSPORTER MGTE
Descriptor:Magnesium transporter MgtE, CALCIUM ION
Authors:Takeda, H., Hattori, M., Nishizawa, T., Yamashita, K., Shah, S.T.A., Caffrey, M., Maturana, A.D., Ishitani, R., Nureki, O.
Deposit date:2014-09-25
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
Nat Commun, 5, 2014
3ZE3
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA7
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Li, D., Pye, V.E., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE4
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - WILD-TYPE
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Lyons, J.A., Pye, V.E., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.702 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE5
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA4
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Vogeley, L., Pye, V.E., Lyons, J.A., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
4BPD
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STRUCTURE DETERMINATION OF AN INTEGRAL MEMBRANE KINASE
Descriptor:DIACYLGLYCEROL KINASE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ZINC ION
Authors:Li, D., Boland, C., Caffrey, M.
Deposit date:2013-05-24
Release date:2014-05-07
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Cell-Free Expression and in Meso Crystallisation of an Integral Membrane Kinase for Structure Determination.
Cell.Mol.Life Sci., 71, 2014
4BPM
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CRYSTAL STRUCTURE OF A HUMAN INTEGRAL MEMBRANE ENZYME
Descriptor:PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE, GLUTATHIONE, ...
Authors:Li, D., Wang, M., Olieric, V., Caffrey, M.
Deposit date:2013-05-27
Release date:2014-04-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
Cryst.Growth Des., 14, 2014
4D2E
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CRYSTAL STRUCTURE OF AN INTEGRAL MEMBRANE KINASE - V2.3
Descriptor:DIACYLGLYCEROL KINASE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Li, D., Boland, C., Caffrey, M.
Deposit date:2014-05-09
Release date:2014-07-23
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Cell-Free Expression and in Meso Crystallisation of an Integral Membrane Kinase for Structure Determination.
Cell.Mol.Life Sci., 71, 2014