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6OM4
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THE STRUCTURE OF MICROCIN C7 BIOSYNTHETIC ENZYME MCCB IN COMPLEX WITH N-FORMYLATED MCCA
Descriptor:MccB protein, Microcin C7, ZINC ION, ...
Authors:Dong, S.-H., Nair, S.K.
Deposit date:2019-04-18
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by theN-formyl of the peptide precursor.
Chem Sci, 10, 2019
6IG0
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFZ
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR2-SSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFU
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR2-DSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFR
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-NTR, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFN
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CRYSTAL STRUCTURE OF TYPE III-A CRISPR CSM COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
Authors:You, L., Wang, J., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFL
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CRYO-EM STRUCTURE OF TYPE III-A CSM-NTR COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFK
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR1 COMPLEX, AMPPNP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IBG
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BACTERIOPHAGE G20C PORTAL PROTEIN CRYSTAL STRUCTURE FOR CONSTRUCT WITH INTACT N-TERMINUS
Descriptor:Portal protein, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-30
Release date:2019-01-23
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6IBC
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THERMOPHAGE P23-45 PROCAPSID
Descriptor:Major head protein
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-29
Release date:2019-02-13
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6I9E
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THERMOPHAGE P23-45 EMPTY EXPANDED CAPSID
Descriptor:Major head protein, Auxiliary protein
Authors:Bayfield, O.W., Klimuk, E., Winkler, D.C., Hesketh, E.L., Chechik, M., Cheng, N., Dykeman, E.C., Minakhin, L., Ranson, N.A., Severinov, K., Steven, A.C., Antson, A.A.
Deposit date:2018-11-23
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GRI
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX
Descriptor:Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, Microcin B17-processing protein McbD, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRH
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH TRUNCATED PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRG
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17, ADP AND PHOSPHATE BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GOS
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-04
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
5XJ0
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T. THERMOPHILUS RNA POLYMERASE HOLOENZYME BOUND WITH GP39 AND GP76
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ooi, W.Y., Murayama, Y., Mekler, V., Minakhin, L., Severinov, K., Yokoyama, S., Sekine, S.
Deposit date:2017-04-28
Release date:2017-12-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (4.004 Å)
Cite:A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation
Nucleic Acids Res., 46, 2018
5W4K
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH KLEBSAZOLICIN AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.7A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.
Deposit date:2017-06-12
Release date:2017-08-30
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
5UI7
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SOLUTION NMR STRUCTURE OF LASSO PEPTIDE KLEBSIDIN
Descriptor:Klebsidin
Authors:Bushin, L.B., Metelev, M., Severinov, K., Seyedsayamdost, M.R.
Deposit date:2017-01-13
Release date:2017-02-08
Last modified:2017-03-29
Method:SOLUTION NMR
Cite:Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
5UI6
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SOLUTION NMR STRUCTURE OF LASSO PEPTIDE ACINETODIN
Descriptor:Acinetodin
Authors:Bushin, L.B., Metelev, M., Severinov, K., Seyedsayamdost, M.R.
Deposit date:2017-01-12
Release date:2017-02-08
Last modified:2017-03-29
Method:SOLUTION NMR
Cite:Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
ACS Chem. Biol., 12, 2017
5NJF
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E (TLDD H262A MUTANT) WITH PENTAPEPTIDE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ALA-ALA-ALA-ALA-ALA, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJC
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E (TLDD E263A MUTANT) WITH HEXAPEPTIDE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, VAL-LEU-GLU-ASP-ARG-ILE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJB
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ACTINONIN BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJA
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ANGIOTENSIN ANALOGUE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, HIS-PRO-PHE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJ9
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH DRVY ANGIOTENSIN FRAGMENT BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ASP-ARG-VAL-TYR, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017