Author results

1NG3
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COMPLEX OF THIO (GLYCINE OXIDASE) WITH ACETYL-GLYCINE
分子名称:Glycine oxidase, PHOSPHATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Settembre, E.C., Dorrestein, P.C., Park, J., Augustine, A., Begley, T.P., Ealick, S.E.
登録日2002-12-16
公開日2003-04-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry, 42, 2003
1NG4
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STRUCTURE OF THIO (GLYCINE OXIDASE) FROM BACILLUS SUBTILIS
分子名称:Glycine oxidase, FLAVIN-ADENINE DINUCLEOTIDE, HYDROGEN PEROXIDE, ...
著者Settembre, E.C., Dorrestein, P.C., Park, J., Augustine, A., Begley, T.P., Ealick, S.E.
登録日2002-12-16
公開日2003-04-08
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry, 42, 2003
1TYG
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STRUCTURE OF THE THIAZOLE SYNTHASE/THIS COMPLEX
分子名称:yjbS, Thiazole biosynthesis protein thiG, PHOSPHATE ION
著者Settembre, E.C., Dorrestein, P.C., Zhai, H., Chatterjee, A., McLafferty, F.W., Begley, T.P., Ealick, S.E.
登録日2004-07-07
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Thiamin Biosynthesis in Bacillus subtilis: Structure of the Thiazole Synthase/Sulfur Carrier Protein Complex
Biochemistry, 43, 2004
1U11
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PURE (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE) FROM THE ACIDOPHILE ACETOBACTER ACETI
分子名称:PurE (N5-carboxyaminoimidazole Ribonucleotide Mutase), CITRIC ACID
著者Settembre, E.C., Chittuluru, J.R., Mill, C.P., Kappock, T.J., Ealick, S.E.
登録日2004-07-14
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Acidophilic adaptations in the structure of Acetobacter aceti N5-carboxyaminoimidazole ribonucleotide mutase (PurE).
Acta Crystallogr.,Sect.D, 60, 2004
4V7Q
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ATOMIC MODEL OF AN INFECTIOUS ROTAVIRUS PARTICLE
分子名称:Core scaffold protein, Intermediate capsid protein VP6, Outer layer protein VP7, ...
著者Settembre, E.C., Chen, J.Z., Dormitzer, P.R., Grigorieff, N., Harrison, S.C.
登録日2010-05-13
公開日2014-07-09
最終更新日2018-01-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic model of an infectious rotavirus particle.
Embo J., 30, 2011
1SD1
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STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH FORMYCIN A
分子名称:5'-methylthioadenosine phosphorylase, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol
著者Lee, J.E., Settembre, E.C., Cornell, K.A., Riscoe, M.K., Sufrin, J.R., Ealick, S.E., Howell, P.L.
登録日2004-02-12
公開日2004-05-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design.
Biochemistry, 43, 2004
1SD2
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STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-METHYLTHIOTUBERCIDIN
分子名称:5'-methylthioadenosine phosphorylase, SULFATE ION, 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
著者Lee, J.E., Settembre, E.C., Cornell, K.A., Riscoe, M.K., Sufrin, J.R., Ealick, S.E., Howell, P.L.
登録日2004-02-12
公開日2004-05-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design.
Biochemistry, 43, 2004
1TGV
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED WITH 5-FLUOROURIDINE AND SULFATE
分子名称:uridine phosphorylase, SULFATE ION, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Sanders, J.M., Begley, T.P., Ealick, S.E.
登録日2004-05-31
公開日2005-06-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of E. coli Uridine Phosphorylase
To be Published, 2004
1TGY
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED WITH URACIL AND RIBOSE 1-PHOSPHATE
分子名称:uridine phosphorylase, RIBOSE-1-PHOSPHATE, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Sanders, J.M., Begley, T.P., Ealick, S.E.
登録日2004-05-31
公開日2005-06-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of E. coli Uridine Phosphorylase
To be Published, 2004
1U1C
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED TO 5-BENZYLACYCLOURIDINE (BAU)
分子名称:Uridine phosphorylase, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1D
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED TO 5-(PHENYLTHIO)ACYCLOURIDINE (PTAU)
分子名称:Uridine phosphorylase, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1E
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED TO 5(PHENYLSELENO)ACYCLOURIDINE (PSAU)
分子名称:Uridine phosphorylase, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1F
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED TO 5-(M-(BENZYLOXY)BENZYL)ACYCLOURIDINE (BBAU)
分子名称:Uridine phosphorylase, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W., Settembre, E.C., Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1G
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STRUCTURE OF E. COLI URIDINE PHOSPHORYLASE COMPLEXED TO 5-(M-(BENZYLOXY)BENZYL)BARBITURIC ACID (BBBA)
分子名称:Uridine phosphorylase, POTASSIUM ION, 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)-6-HYDROXYPYRIMIDINE-2,4(1H,3H)-DIONE
著者Bu, W., Settembre, E.C., Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
3FMG
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STRUCTURE OF ROTAVIRUS OUTER CAPSID PROTEIN VP7 TRIMER IN COMPLEX WITH A NEUTRALIZING FAB
分子名称:Fab of neutralizing antibody 4F8, light chain, heavy chain, ...
著者Aoki, S.T., Settembre, E.C., Trask, S.D., Greenberg, H.B., Harrison, S.C., Dormitzer, P.R.
登録日2008-12-22
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.
Science, 324, 2009
3GZT
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VP7 RECOATED ROTAVIRUS DLP
分子名称:Outer capsid glycoprotein VP7, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
著者Chen, J.Z., Settembre, E.C., Harrison, S.C., Grigorieff, N.
登録日2009-04-07
公開日2009-07-14
最終更新日2011-07-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM
Proc.Natl.Acad.Sci.USA, 106, 2009
3GZU
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VP7 RECOATED ROTAVIRUS DLP
分子名称:Inner capsid protein VP2, Intermediate capsid protein VP6, ZINC ION
著者Chen, J.Z., Settembre, E.C., Harrison, S.C., Grigorieff, N.
登録日2009-04-07
公開日2009-07-14
最終更新日2011-07-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 106, 2009
3P5B
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THE STRUCTURE OF THE LDLR/PCSK9 COMPLEX REVEALS THE RECEPTOR IN AN EXTENDED CONFORMATION
分子名称:Proprotein convertase subtilisin/kexin type 9, Low density lipoprotein receptor variant, CALCIUM ION
著者Lo Surdo, P., Bottomley, M.J., Calzetta, A., Settembre, E.C., Cirillo, A., Pandit, S., Ni, Y., Hubbard, B., Sitlani, A., Carfi, A.
登録日2010-10-08
公開日2011-10-26
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3P5C
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THE STRUCTURE OF THE LDLR/PCSK9 COMPLEX REVEALS THE RECEPTOR IN AN EXTENDED CONFORMATION
分子名称:Proprotein convertase subtilisin/kexin type 9, Low density lipoprotein receptor variant, CALCIUM ION
著者Lo Surdo, P., Bottomley, M.J., Calzetta, A., Settembre, E.C., Cirillo, A., Pandit, S., Ni, Y., Hubbard, B., Sitlani, A., Carfi, A.
登録日2010-10-08
公開日2011-10-26
最終更新日2015-05-27
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3RKI
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STRUCTURAL BASIS FOR IMMUNIZATION WITH POST-FUSION RSV F TO ELICIT HIGH NEUTRALIZING ANTIBODY TITERS
分子名称:Fusion glycoprotein F0, N-ACETYL-D-GLUCOSAMINE
著者Swanson, K.A., Settembre, E.C., Shaw, C.A., Dey, A.K., Rappuoli, R., Mandl, C.W., Dormitzer, P.D., Carfi, A.
登録日2011-04-18
公開日2011-05-18
最終更新日2011-08-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SKU
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HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE HUMAN RECEPTOR NECTIN-1
分子名称:Glycoprotein D, Poliovirus receptor-related protein 1, N-ACETYL-D-GLUCOSAMINE, ...
著者Di Giovine, P., Settembre, E.C., Bhargava, A.K., Luftig, M.A., Lou, H., Cohen, G.H., Eisenberg, R.J., Krummenacher, C., Carfi, A.
登録日2011-06-23
公開日2011-10-12
最終更新日2011-10-19
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of herpes simplex virus glycoprotein d bound to the human receptor nectin-1.
Plos Pathog., 7, 2011
4AU6
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LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES
分子名称:RNA-DEPENDENT RNA POLYMERASE
著者Estrozi, L.F., Settembre, E.C., Goret, G., McClain, B., Zhang, X., Chen, J.Z., Grigorieff, N., Harrison, S.C.
登録日2012-05-14
公開日2012-06-13
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Location of the Dsrna-Dependent Polymerase, Vp1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
4F5X
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LOCATION OF THE DSRNA-DEPENDENT POLYMERASE, VP1, IN ROTAVIRUS PARTICLES
分子名称:VP2 protein, Intermediate capsid protein VP6, RNA-directed RNA polymerase, ...
著者Estrozi, L.F., Settembre, E.C., Goret, G., McClain, B., Zhang, X., Chen, J.Z., Grigorieff, N., Harrison, S.C.
登録日2012-05-13
公開日2012-10-24
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
4HHE
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QUINOLINATE SYNTHASE FROM PYROCOCCUS FURIOSUS
分子名称:Quinolinate synthase A, CHLORIDE ION
著者Soriano, E.V., Zhang, Y., Settembre, E.C., Colabroy, K., Sanders, J.M., Dorrestein, P.C., Begley, T.P., Ealick, S.E.
登録日2012-10-09
公開日2013-08-28
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Active-site models for complexes of quinolinate synthase with substrates and intermediates.
Acta Crystallogr.,Sect.D, 69, 2013
5C6T
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CRYSTAL STRUCTURE OF HCMV GLYCOPROTEIN B IN COMPLEX WITH 1G2 FAB
分子名称:Envelope glycoprotein B, 1G2 Fab heavy chain, 1G2 Fab light chain, ...
著者Chandramouli, S., Ciferri, C., Settembre, E.C., Carfi, A.
登録日2015-06-23
公開日2015-09-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody.
Nat Commun, 6, 2015
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