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3O2D
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BU of 3o2d by Molmil
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Descriptor: T-cell surface glycoprotein CD4, ibalizumab heavy chain, ibalizumab light chain
Authors:Freeman, M.M, Seaman, M.S, Rits-Volloch, S, Hong, X, Ho, D.D, Chen, B.
Deposit date:2010-07-22
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody.
Structure, 18, 2010
2XRA
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BU of 2xra by Molmil
crystal structure of the HK20 Fab in complex with a gp41 mimetic 5- Helix
Descriptor: HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN, ...
Authors:Sabin, C, Corti, D, Buzon, V, Seaman, M.S, Lutje Hulsik, D, Hinz, A, Vanzetta, F, Agatic, G, Silacci, C, Langedijk, J.P.M, Mainetti, L, Scarlatti, G, Sallusto, F, Weiss, R, Lanzavecchia, A, Weissenhorn, W.
Deposit date:2010-09-13
Release date:2010-12-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
6E8W
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BU of 6e8w by Molmil
MPER-TM Domain of HIV-1 envelope glycoprotein (Env)
Descriptor: Envelope glycoprotein gp160
Authors:Fu, Q, Shaik, M.M, Cai, Y, Ghantous, F, Piai, A, Peng, H, Rits-Volloch, S, Liu, Z, Harrison, S.C, Seaman, M.S, Chen, B, Chou, J.J.
Deposit date:2018-07-31
Release date:2018-09-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6UJV
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BU of 6ujv by Molmil
Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2)
Descriptor: Envelope glycoprotein GP41
Authors:Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J.
Deposit date:2019-10-03
Release date:2020-05-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.
Nat Commun, 11, 2020
6UJU
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BU of 6uju by Molmil
Structure of the HIV-1 gp41 transmembrane domain and cytoplasmic tail (LLP2)
Descriptor: Envelope glycoprotein GP41
Authors:Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J.
Deposit date:2019-10-03
Release date:2020-05-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.
Nat Commun, 11, 2020
6V4T
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BU of 6v4t by Molmil
MPER-TMD of HIV-1 Env bound with the entry inhibitor S2C3
Descriptor: 4-[10-(9-azanyl-2,3-dihydro-1~{H}-cyclopenta[b]quinolin-4-yl)decyl]-2,3-dihydro-1~{H}-cyclopenta[b]quinolin-9-amine, Envelope glycoprotein gp160
Authors:Xiao, T, Frey, G, Fu, Q, Lavine, C.L, Scott, D.A, Seaman, M.S, Chou, J.J, Chen, B.
Deposit date:2019-11-30
Release date:2020-04-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes.
Nat.Chem.Biol., 16, 2020
4RQQ
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BU of 4rqq by Molmil
Crystal structure of human Fab PGDM1400, a broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: Human anti-HIV-1 antibody PGDM1400 heavy chain, Human anti-HIV-1 antibody PGDM1400 light chain
Authors:Julien, J.-P, Wilson, I.A.
Deposit date:2014-11-04
Release date:2014-11-19
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
Proc.Natl.Acad.Sci.USA, 111, 2014
8C8T
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BU of 8c8t by Molmil
cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Baquero, E, Molinos-Albert, L, Mouquet, H.
Deposit date:2023-01-21
Release date:2023-07-05
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.
Cell Host Microbe, 31, 2023
7PC2
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HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC IgG Fab heavy chain, ...
Authors:Fernandez, I, Bontems, F, Pehau-Arnaudet, G, Rey, F.
Deposit date:2021-08-03
Release date:2022-02-23
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.
J.Exp.Med., 219, 2022
5JYN
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BU of 5jyn by Molmil
Structure of the transmembrane domain of HIV-1 gp41 in bicelle
Descriptor: Envelope glycoprotein gp160
Authors:Dev, J, Fu, Q, Park, D, Chen, B, Chou, J.J.
Deposit date:2016-05-14
Release date:2016-06-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for membrane anchoring of HIV-1 envelope spike.
Science, 353, 2016
6VY2
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BU of 6vy2 by Molmil
Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
Authors:Chan, K.-W, Kong, X.P.
Deposit date:2020-02-25
Release date:2020-05-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.86 Å)
Cite:VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27, 2020
4XMK
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BU of 4xmk by Molmil
Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424 in complex with JR-FL V3 peptide
Descriptor: HIV-1 JR-FL gp120 V3 peptide, Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424
Authors:Kong, X.-P, Pan, R.
Deposit date:2015-01-14
Release date:2015-07-08
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (3.179 Å)
Cite:Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
J.Virol., 89, 2015
4XML
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BU of 4xml by Molmil
Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424
Descriptor: Heavy chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424, Light chain of HIV-1 gp120 V3-specific human monoclonal antibody 2424
Authors:Pan, R, Kong, X.-P.
Deposit date:2015-01-14
Release date:2015-07-08
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
J.Virol., 89, 2015
5WB9
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BU of 5wb9 by Molmil
Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
Authors:Gohain, N, Tolbert, W, Pazgier, M.
Deposit date:2017-06-28
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses.
Cell, 173, 2018
6BCK
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BU of 6bck by Molmil
Crystal Structure of Broadly Neutralizing Antibody N49P7 in Complex with HIV-1 Clade AE strain 93TH057 gp120 core.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, N49P7 Fab heavy chain of N29P7 IgG, ...
Authors:Tolbert, W.D, Gohain, N, Pazgier, M.
Deposit date:2017-10-20
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses.
Cell, 173, 2018
7KJ3
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BU of 7kj3 by Molmil
SARS-CoV-2 Spike Glycoprotein with two ACE2 Bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B.
Deposit date:2020-10-25
Release date:2020-11-11
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Nat.Struct.Mol.Biol., 28, 2021
7KJ5
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BU of 7kj5 by Molmil
SARS-CoV-2 Spike Glycoprotein, prefusion with one RBD up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B.
Deposit date:2020-10-25
Release date:2020-11-11
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Nat.Struct.Mol.Biol., 28, 2021
7KJ2
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BU of 7kj2 by Molmil
SARS-CoV-2 Spike Glycoprotein with one ACE2 Bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B.
Deposit date:2020-10-25
Release date:2020-11-11
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Nat.Struct.Mol.Biol., 28, 2021
7KJ4
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BU of 7kj4 by Molmil
SARS-CoV-2 Spike Glycoprotein with three ACE2 Bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Zhang, J, Xiao, T.S, Cai, Y.F, Chen, B.
Deposit date:2020-10-25
Release date:2020-11-11
Last modified:2021-02-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent.
Nat.Struct.Mol.Biol., 28, 2021
7U04
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BU of 7u04 by Molmil
IOMA class antibody ACS101
Descriptor: GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-02-17
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
7U0K
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BU of 7u0k by Molmil
IOMA class antibody Fab ACS124
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-02-18
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022
7U5G
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BU of 7u5g by Molmil
ACS122 Fab
Descriptor: ACS122 Fab Heavy chain, ACS122 Fab Light chain
Authors:Farokhi, E, Stanfield, R.L, Wilson, I.A.
Deposit date:2022-03-02
Release date:2022-11-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer.
Plos Pathog., 18, 2022
7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
Descriptor: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2022-01-26
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
Descriptor: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
Authors:Julien, J.-P, Diwanji, D.C, Wilson, I.A.
Deposit date:2013-11-22
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
7Z3A
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BU of 7z3a by Molmil
AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACS101 heavy chain, ...
Authors:van Schooten, J, Ward, A.
Deposit date:2022-03-02
Release date:2022-08-10
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.
Nat Commun, 13, 2022

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