Author results

4IW3
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CRYSTAL STRUCTURE OF A PSEUDOMONAS PUTIDA PROLYL-4-HYDROXYLASE (P4H) IN COMPLEX WITH ELONGATION FACTOR TU (EF-TU)
Descriptor:Putative uncharacterized protein, Elongation factor Tu-A, MANGANESE (II) ION, ...
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-01-23
Release date:2014-01-29
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4J0Q
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CRYSTAL STRUCTURE OF PSEUDOMONAS PUTIDA ELONGATION FACTOR TU (EF-TU)
Descriptor:Elongation factor Tu-A, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-01-31
Release date:2014-02-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4J25
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CRYSTAL STRUCTURE OF A PSEUDOMONAS PUTIDA PROLYL-4-HYDROXYLASE (P4H)
Descriptor:Putative uncharacterized protein, MANGANESE (II) ION, N-OXALYLGLYCINE
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-02-04
Release date:2014-02-05
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4JAA
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKYRIN REPEAT DOMAIN-(D)LEU PEPTIDE
Descriptor:Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(d)LEU, ZINC ION, ...
Authors:Scotti, J.S., Ge, W., McDonough, M.A., Schofield, C.J.
Deposit date:2013-02-18
Release date:2014-02-19
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure of an oxygenase in complex with substrate
To be Published
4NR1
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKYRIN REPEAT DOMAIN-(D)ALLYL-GLY PEPTIDE
Descriptor:Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)allyl glycine, ZINC ION, ...
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-26
Release date:2015-01-21
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of an oxygenase in complex with substrate
To be Published
4NHK
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CRYSTAL STRUCTURE OF TPA1P FROM SACCHAROMYCES CEREVISIAE, TERMINATION AND POLYADENYLATION PROTEIN 1, IN COMPLEX WITH PYRIDINE-2,4-DICARBOXYLIC ACID (2,4-PDCA)
Descriptor:PKHD-type hydroxylase TPA1, MANGANESE (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, ...
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-05
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases.
Structure, 23, 2015
4NHL
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CRYSTAL STRUCTURE OF TPA1P FROM SACCHAROMYCES CEREVISIAE, TERMINATION AND POLYADENYLATION PROTEIN 1, IN COMPLEX WITH N-OXALYLGLYCINE (NOG)
Descriptor:PKHD-type hydroxylase TPA1, MANGANESE (II) ION, N-OXALYLGLYCINE
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-05
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases.
Structure, 23, 2015
4NHM
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CRYSTAL STRUCTURE OF TPA1P FROM SACCHAROMYCES CEREVISIAE, TERMINATION AND POLYADENYLATION PROTEIN 1, IN COMPLEX WITH N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE (IOX3/UN9)
Descriptor:PKHD-type hydroxylase TPA1, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, MANGANESE (II) ION, ...
Authors:Scotti, J.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-05
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases.
Structure, 23, 2015
4B7E
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKYRIN REPEAT DOMAIN-LEU PEPTIDE (20-MER)
Descriptor:HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR, CONSENSUS ANKYRIN REPEAT DOMAIN-LEU, ZINC ION, ...
Authors:Chowdhury, R., Ge, W., Schofield, C.J.
Deposit date:2012-08-17
Release date:2013-01-23
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor.
Angew. Chem. Int. Ed. Engl., 52, 2013
4B7K
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FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKYRIN REPEAT DOMAIN-SER PEPTIDE (20-MER)
Descriptor:HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR, CONSENSUS ANKYRIN REPEAT DOMAIN-SER, ZINC ION, ...
Authors:Chowdhury, R., Ge, W., Schofield, C.J.
Deposit date:2012-08-20
Release date:2013-01-23
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor.
Angew. Chem. Int. Ed. Engl., 52, 2013
4NHX
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CRYSTAL STRUCTURE OF HUMAN OGFOD1, 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN CONTAINING 1, IN COMPLEX WITH N-OXALYLGLYCINE (NOG)
Descriptor:2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, MANGANESE (II) ION, SODIUM ION, ...
Authors:Horita, S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-05
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases.
Structure, 23, 2015
4NHY
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CRYSTAL STRUCTURE OF HUMAN OGFOD1, 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN CONTAINING 1, IN COMPLEX WITH PYRIDINE-2,4-DICARBOXYLIC ACID (2,4-PDCA)
Descriptor:2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, MANGANESE (II) ION, GLYCEROL, ...
Authors:Horita, S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-05
Release date:2014-11-19
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases.
Structure, 23, 2015
4NJ4
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CRYSTAL STRUCTURE OF HUMAN ALKBH5
Descriptor:RNA demethylase ALKBH5, MANGANESE (II) ION, NITRATE ION, ...
Authors:Aik, W.S., McDonough, M.A., Schofield, C.J.
Deposit date:2013-11-08
Release date:2014-01-15
Last modified:2014-05-21
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.
Nucleic Acids Res., 42, 2014