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3CF6
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STRUCTURE OF EPAC2 IN COMPLEX WITH CYCLIC-AMP AND RAP
Descriptor:Rap guanine nucleotide exchange factor (GEF) 4, Ras-related protein Rap-1b, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, ...
Authors:Rehmann, H., Arias-Palomo, E., Hadders, M.A., Schwede, F., Llorca, O., Bos, J.L.
Deposit date:2008-03-02
Release date:2008-07-29
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature, 455, 2008
4KL1
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HCN4 CNBD IN COMPLEX WITH CGMP
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, CYCLIC GUANOSINE MONOPHOSPHATE, ACETATE ION, ...
Authors:Lolicato, M., Arrigoni, C., Zucca, S., Nardini, M., Bucchi, A., Schroeder, I., Simmons, K., Bolognesi, M., DiFrancesco, D., Schwede, F., Fishwick, C.W.G., Johnson, A.P.K., Thiel, G., Moroni, A.
Deposit date:2013-05-07
Release date:2014-04-30
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat.Chem.Biol., 10, 2014
4NVP
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STRUCTURE OF THE CYCLIC NUCLEOTIDE-BINDING DOMAIN OF HCN4 CHANNEL COMPLEXED WITH 7-CH-CAMP
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, (2S,4aR,6R,7R,7aS)-6-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide
Authors:Alfieri, A., Moroni, A.
Deposit date:2013-12-05
Release date:2014-03-19
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels.
Acs Chem.Biol., 9, 2014
4RLE
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CRYSTAL STRUCTURE OF THE C-DI-AMP BINDING PII-LIKE PROTEIN DARA
Descriptor:Uncharacterized protein YaaQ, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, NICKEL (II) ION
Authors:Dickmanns, A., Neumann, P., Ficner, R.
Deposit date:2014-10-16
Release date:2014-12-03
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA.
J.Biol.Chem., 290, 2015
6FTF
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REGULATORY SUBUNIT OF A CAMP-INDEPENDENT PROTEIN KINASE A FROM TRYPANOSOMA CRUZI AT 1.09 A RESOLUTION
Descriptor:Protein kinase A regulatory subunit, putative, 1,2-ETHANEDIOL, ...
Authors:Volpato Santos, Y., Lorentzen, E., Basquin, J., Boshart, M.
Deposit date:2018-02-21
Release date:2019-04-03
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.091519 Å)
Cite:Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.
Nat Commun, 10, 2019
1C1Y
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CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD).
Descriptor:RAS-RELATED PROTEIN RAP-1A, PROTO-ONCOGENE SERINE/THREONINE PROTEIN KINASE RAF-1, MAGNESIUM ION, ...
Authors:Nassar, N.
Deposit date:1999-07-22
Release date:1999-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.
Nature, 375, 1995