Author results

1OW1
  • Download 1ow1
  • View 1ow1
Molmil generated image of 1ow1
CRYSTAL STRUCTURE OF THE SPOC DOMAIN OF THE HUMAN TRANSCRIPTIONAL COREPRESSOR, SHARP.
Descriptor:SMART/HDAC1 associated repressor protein
Authors:Schwabe, J.W., Ariyoshi, M.
Deposit date:2003-03-28
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling
Genes Dev., 17, 2003
4AA6
  • Download 4aa6
  • View 4aa6
Molmil generated image of 4aa6
THE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
Descriptor:ESTROGEN RECEPTOR, 5'-D(*CP*TP*AP*AP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP *CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP *CP*TP*TP*A)-3', ...
Authors:Schwabe, J.W., Chapman, L., Rhodes, D.
Deposit date:2011-11-30
Release date:2011-12-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Oestrogen Receptor Recognizes an Imperfectly Palindromic Response Element Through an Alternative Side-Chain Conformation.
Structure, 3, 1995
1HCP
  • Download 1hcp
  • View 1hcp
Molmil generated image of 1hcp
DNA RECOGNITION BY THE OESTROGEN RECEPTOR: FROM SOLUTION TO THE CRYSTAL
Descriptor:HUMAN/CHICKEN ESTROGEN RECEPTOR, ZINC ION
Authors:Schwabe, J.W.R., Rhodes, D., Neuhaus, D.
Deposit date:1993-11-23
Release date:1995-11-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:DNA recognition by the oestrogen receptor: from solution to the crystal.
Structure, 1, 1993
1HCQ
  • Download 1hcq
  • View 1hcq
Molmil generated image of 1hcq
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
Descriptor:DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ...
Authors:Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
Deposit date:1995-01-04
Release date:1995-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Cell(Cambridge,Mass.), 75, 1993
1ZFD
  • Download 1zfd
  • View 1zfd
Molmil generated image of 1zfd
SWI5 ZINC FINGER DOMAIN 2, NMR, 45 STRUCTURES
Descriptor:SWI5, ZINC ION
Authors:Neuhaus, D., Nakaseko, Y., Schwabe, J.W.R., Rhodes, D., Klug, A.
Deposit date:1996-04-04
Release date:1996-10-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.
J.Mol.Biol., 228, 1992
2DRP
  • Download 2drp
  • View 2drp
Molmil generated image of 2drp
THE CRYSTAL STRUCTURE OF A TWO ZINC-FINGER PEPTIDE REVEALS AN EXTENSION TO THE RULES FOR ZINC-FINGER/DNA RECOGNITION
Descriptor:DNA (5'-D(*CP*TP*AP*AP*TP*AP*AP*GP*GP*AP*TP*AP*AP*CP*GP*TP*C P*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*GP*TP*TP*AP*TP*CP*CP*TP*TP*AP*T P*TP*A)-3'), PROTEIN (TRAMTRACK DNA-BINDING DOMAIN), ...
Authors:Fairall, L., Schwabe, J.W.R., Chapman, L., Finch, J.T., Rhodes, D.
Deposit date:1994-06-06
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition.
Nature, 366, 1993
2L5G
  • Download 2l5g
  • View 2l5g
Molmil generated image of 2l5g
CO-ORDINATES AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF GPS2 53-90 AND SMRT 167-207
Descriptor:G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J., Yang, J., Neuhaus, D., Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
2MWI
  • Download 2mwi
  • View 2mwi
Molmil generated image of 2mwi
THE STRUCTURE OF THE CARBOXY-TERMINAL DOMAIN OF DNTTIP1
Descriptor:Deoxynucleotidyltransferase terminal-interacting protein 1
Authors:Schwabe, J.W.R., Muskett, F.W., Itoh, T.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
2YHO
  • Download 2yho
  • View 2yho
Molmil generated image of 2yho
THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENT DEGRADATION OF THE LDL RECEPTOR
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ZINC ION, ...
Authors:Fairall, L., Goult, B.T., Millard, C.J., Tontonoz, P., Schwabe, J.W.R.
Deposit date:2011-05-04
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25, 2011
5FXY
  • Download 5fxy
  • View 5fxy
Molmil generated image of 5fxy
STRUCTURE OF THE HUMAN RBBP4:MTA1(464-546) COMPLEX
Descriptor:HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1
Authors:Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.
Deposit date:2016-03-03
Release date:2016-05-18
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
5ICN
  • Download 5icn
  • View 5icn
Molmil generated image of 5icn
HDAC1:MTA1 IN COMPLEX WITH INOSITOL-6-PHOSPHATE AND A NOVEL PEPTIDE INHIBITOR BASED ON HISTONE H4
Descriptor:Metastasis-associated protein MTA1, Histone deacetylase 1, GLY-ALA-6A0-ARG-HIS, ...
Authors:Millard, C.J., Robertson, N.S., Watson, P.J., Jameson, A.G., Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
6G16
  • Download 6g16
  • View 6g16
Molmil generated image of 6g16
STRUCTURE OF THE HUMAN RBBP4:MTA1(464-546) COMPLEX SHOWING LOOP EXCHANGE
Descriptor:Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.
Deposit date:2018-03-20
Release date:2018-06-13
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
To be published
1MEY
  • Download 1mey
  • View 1mey
Molmil generated image of 1mey
CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA
Descriptor:DNA (5'-D(*AP*TP*GP*AP*GP*GP*CP*AP*GP*AP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*TP*(C38)P*A)-3'), CONSENSUS ZINC FINGER, ...
Authors:Kim, C.A., Berg, J.M.
Deposit date:1996-09-27
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A 2.2 A Resolution Crystal Structure of a Designed Zinc Finger Protein Bound to DNA
Nat.Struct.Biol., 3, 1996
1NCS
  • Download 1ncs
  • View 1ncs
Molmil generated image of 1ncs
NMR STUDY OF SWI5 ZINC FINGER DOMAIN 1
Descriptor:TRANSCRIPTIONAL FACTOR SWI5, ZINC ION
Authors:Dutnall, R.N., Neuhaus, D., Rhodes, D.
Deposit date:1996-02-26
Release date:1996-06-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the first zinc finger domain of SWI5: a novel structural extension to a common fold.
Structure, 4, 1996