Author results

1AJ7
  • Download 1aj7
  • View 1aj7
Molmil generated image of 1aj7
IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Descriptor:IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN), IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Authors:Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
Deposit date:1997-05-15
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
2RCS
  • Download 2rcs
  • View 2rcs
Molmil generated image of 2rcs
IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Descriptor:IMMUNOGLOBULIN 48G7 GERMLINE FAB
Authors:Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
Deposit date:1997-05-14
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
1HKL
  • Download 1hkl
  • View 1hkl
Molmil generated image of 1hkl
FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY
Descriptor:48G7 FAB
Authors:Wedemayer, G.J., Wang, L.H., Patten, P.A., Schultz, P.G., Stevens, R.C.
Deposit date:1996-12-20
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Crystal structures of the free and liganded form of an esterolytic catalytic antibody.
J.Mol.Biol., 268, 1997
1GAF
  • Download 1gaf
  • View 1gaf
Molmil generated image of 1gaf
48G7 HYBRIDOMA LINE FAB COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Descriptor:CHIMERIC 48G7 FAB, 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Authors:Wedemayer, G.J., Patten, P.A., Stevens, R.C., Schultz, P.G.
Deposit date:1996-02-06
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The immunological evolution of catalysis.
Science, 271, 1996
1JES
  • Download 1jes
  • View 1jes
Molmil generated image of 1jes
CRYSTAL STRUCTURE OF A COPPER-MEDIATED BASE PAIR IN DNA
Descriptor:5'-D(*CP*GP*CP*GP*(DPY)P*AP*TP*(DRP)P*CP*GP*CP*G)-3', COPPER (II) ION
Authors:Atwell, S., Meggers, E., Spraggon, G., Schultz, P.G.
Deposit date:2001-06-18
Release date:2001-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a Copper-Mediated Base Pair in DNA
J.Am.Chem.Soc., 123, 2001
1KEL
  • Download 1kel
  • View 1kel
Molmil generated image of 1kel
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID)
Descriptor:28B4 FAB, 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID
Authors:Hsieh-Wilson, L.C., Schultz, P.G., Stevens, R.C.
Deposit date:1996-04-16
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1KEM
  • Download 1kem
  • View 1kem
Molmil generated image of 1kem
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT
Descriptor:28B4 FAB
Authors:Hsieh-Wilson, L.C., Schultz, P.G., Stevens, R.C.
Deposit date:1996-04-16
Release date:1996-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1PVP
  • Download 1pvp
  • View 1pvp
Molmil generated image of 1pvp
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7
Descriptor:34-MER, Recombinase CRE
Authors:Baldwin, E.P., Martin, S.S., Abel, J., Gelato, K.A., Kim, H., Schultz, P.G., Santoro, S.W.
Deposit date:2003-06-28
Release date:2004-02-17
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
1PVQ
  • Download 1pvq
  • View 1pvq
Molmil generated image of 1pvq
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7
Descriptor:34-MER, Recombinase CRE
Authors:Baldwin, E.P., Martin, S.S., Abel, J., Gelato, K.A., Kim, H., Schultz, P.G., Santoro, S.W.
Deposit date:2003-06-28
Release date:2004-02-17
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
1PVR
  • Download 1pvr
  • View 1pvr
Molmil generated image of 1pvr
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE
Descriptor:34-MER, Recombinase CRE
Authors:Baldwin, E.P., Martin, S.S., Abel, J., Gelato, K.A., Kim, H., Schultz, P.G., Santoro, S.W.
Deposit date:2003-06-28
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
1A4J
  • Download 1a4j
  • View 1a4j
Molmil generated image of 1a4j
DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR
Descriptor:IMMUNOGLOBULIN, DIELS ALDER CATALYTIC ANTIBODY (LIGHT CHAIN), DIELS ALDER CATALYTIC ANTIBODY (HEAVY CHAIN)
Authors:Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C.
Deposit date:1998-01-30
Release date:1998-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
1A4K
  • Download 1a4k
  • View 1a4k
Molmil generated image of 1a4k
DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE
Descriptor:ANTIBODY FAB, CADMIUM ION, [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID
Authors:Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C.
Deposit date:1998-01-30
Release date:1998-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Immunological origins of binding and catalysis in a Diels-Alderase antibody.
Science, 279, 1998
1CKP
  • Download 1ckp
  • View 1ckp
Molmil generated image of 1ckp
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B
Descriptor:PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B, 1,2-ETHANEDIOL
Authors:Gray, N.S., Thunnissen, A.M.W.H., Schultz, P.G., Kim, S.H.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Science, 281, 1998
1D5B
  • Download 1d5b
  • View 1d5b
Molmil generated image of 1d5b
UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY
Descriptor:chimeric OXY-COPE catalytic ANTIBODY AZ-28 (light chain), chimeric OXY-COPE catalytic ANTIBODY AZ-28 (HEAVY chain), CADMIUM ION
Authors:Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.
Deposit date:1999-10-06
Release date:2000-02-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
1D5I
  • Download 1d5i
  • View 1d5i
Molmil generated image of 1d5i
UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY
Descriptor:CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN), CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), CADMIUM ION
Authors:Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.
Deposit date:1999-10-07
Release date:2000-02-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
1D6V
  • Download 1d6v
  • View 1d6v
Molmil generated image of 1d6v
CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION
Descriptor:CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (LIGHT CHAIN), CHIMERIC GERMLINE PRECURSOR OF OXY-COPE CATALYTIC ANTIBODY AZ-28 (HEAVY CHAIN), CADMIUM ION, ...
Authors:Mundorff, E.C., Hanson, M.A., Schultz, P.G., Stevens, R.C.
Deposit date:1999-10-15
Release date:2000-02-09
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement.
Biochemistry, 39, 2000
1FL5
  • Download 1fl5
  • View 1fl5
Molmil generated image of 1fl5
THE UNLIGANDED GERMLINE PRECURSOR TO THE SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4.
Descriptor:ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4, SULFATE ION
Authors:Yin, J., Mundorff, E.C., Yang, P.L., Wendt, K.U., Hanway, D., Stevens, R.C., Schultz, P.G.
Deposit date:2000-08-11
Release date:2001-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A comparative analysis of the immunological evolution of antibody 28B4.
Biochemistry, 40, 2001
1FL6
  • Download 1fl6
  • View 1fl6
Molmil generated image of 1fl6
THE HAPTEN COMPLEXED GERMLINE PRECURSOR TO SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4
Descriptor:ANTIBODY GERMLINE PRECURSOR TO 28B4, 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID
Authors:Yin, J., Mundorff, E.C., Yang, P.L., Wendt, K.U., Hanway, D., Stevens, R.C., Schultz, P.G.
Deposit date:2000-08-11
Release date:2001-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A comparative analysis of the immunological evolution of antibody 28B4.
Biochemistry, 40, 2001
1N7M
  • Download 1n7m
  • View 1n7m
Molmil generated image of 1n7m
GERMLINE 7G12 WITH N-METHYLMESOPORPHYRIN
Descriptor:Germline Metal Chelatase Catalytic Antibody, chain H, chain L, ...
Authors:Yin, J., Andryski, S.E., Beuscher IV, A.E., Stevens, R.C., Schultz, P.G.
Deposit date:2002-11-15
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NGW
  • Download 1ngw
  • View 1ngw
Molmil generated image of 1ngw
CHIMERIC AFFINITY MATURED FAB 7G12 COMPLEXED WITH MESOPORPHYRIN
Descriptor:Mature Metal Chelatase Catalytic Antibody, Light chain, Heavy chain, ...
Authors:Yin, J., Andryski, S.E., Beuscher IV, A.E., Stevens, R.C., Schultz, P.G.
Deposit date:2002-12-18
Release date:2003-02-04
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NGX
  • Download 1ngx
  • View 1ngx
Molmil generated image of 1ngx
CHIMERIC GERMLINE FAB 7G12 WITH JEFFAMINE FRAGMENT BOUND
Descriptor:Germline Metal Chelatase Catalytic Antibody, Light chain, Heavy chain, ...
Authors:Yin, J., Andryski, S.E., Beuscher, A.B., Stevens, R.C., Schultz, P.G.
Deposit date:2002-12-18
Release date:2003-03-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NGY
  • Download 1ngy
  • View 1ngy
Molmil generated image of 1ngy
CHIMERIC MATURE FAB 7G12-APO
Descriptor:Mature Metal Chelatase Catalytic Antibody, Light chain, Heavy chain
Authors:Yin, J., Andryski, S.A., Beuscher, A.B., Stevens, R.C., Schultz, P.G.
Deposit date:2002-12-18
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
1NGZ
  • Download 1ngz
  • View 1ngz
Molmil generated image of 1ngz
CHIMERIC GERMLINE FAB 7G12-APO
Descriptor:Germline Metal Chelatase Catalytic Antibody, Light chain, Heavy chain
Authors:Yin, J., Andryski, S.A., Beuscher, A.B., Stevens, R.C., Schultz, P.G.
Deposit date:2002-12-18
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
1T6H
  • Download 1t6h
  • View 1t6h
Molmil generated image of 1t6h
CRYSTAL STRUCTURE T4 LYSOZYME INCORPORATING AN UNNATURAL AMINO ACID P-IODO-L-PHENYLALANINE AT POSITION 153
Descriptor:Lysozyme, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Spraggon, G., Xie, J., Wang, L., Wu, N., Brock, A., Schultz, P.G.
Deposit date:2004-05-06
Release date:2004-10-26
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.
Nat.Biotechnol., 22, 2004
1U7D
  • Download 1u7d
  • View 1u7d
Molmil generated image of 1u7d
CRYSTAL STRUCTURE OF APO M. JANNASHII TYROSYL-TRNA SYNTHETASE
Descriptor:Tyrosyl-tRNA synthetase
Authors:Zhang, Y., Wang, L., Schultz, P.G., Wilson, I.A.
Deposit date:2004-08-03
Release date:2005-05-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase (TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine.
Protein Sci., 14, 2005
<123>