Author results

1VPR
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CRYSTAL STRUCTURE OF A LUCIFERASE DOMAIN FROM THE DINOFLAGELLATE LINGULODINIUM POLYEDRUM
Descriptor:luciferase
Authors:Schultz, L.W., Liu, L., Cegielski, M., Hastings, J.W.
Deposit date:2004-11-15
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a pH-regulated luciferase catalyzing the bioluminescent oxidation of an open tetrapyrrole
Proc.Natl.Acad.Sci.USA, 102, 2005
1A7X
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FKBP12-FK1012 COMPLEX
Descriptor:FKBP12, BENZYL-CARBAMIC ACID [8-DEETHYL-ASCOMYCIN-8-YL]ETHYL ESTER
Authors:Schultz, L.W., Clardy, J.
Deposit date:1998-03-18
Release date:1998-06-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chemical inducers of dimerization: the atomic structure of FKBP12-FK1012A-FKBP12.
Bioorg.Med.Chem.Lett., 8, 1998
1TXX
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ACTIVE-SITE VARIANT OF E.COLI THIOREDOXIN
Descriptor:PROTEIN (THIOREDOXIN), COPPER (II) ION
Authors:Schultz, L.W., Chivers, P.T., Raines, R.T.
Deposit date:1999-04-07
Release date:1999-09-13
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The CXXC motif: crystal structure of an active-site variant of Escherichia coli thioredoxin.
Acta Crystallogr.,Sect.D, 55, 1999
3RSD
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STRUCTURE OF THE D121N VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A
Authors:Schultz, L.W., Quirk, D.J., Raines, R.T.
Deposit date:1998-02-05
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
3RSP
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STRUCTURE OF THE P93G VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, CHLORIDE ION
Authors:Schultz, L.W., Hargraves, S.R., Klink, T.A., Raines, R.T.
Deposit date:1997-10-20
Release date:1998-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and stability of the P93G variant of ribonuclease A.
Protein Sci., 7, 1998
4NNR
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FKBP13-FK506 COMPLEX
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP2, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
Authors:Schultz, L.W., Martin, P.K., Liang, J., Schreiber, S.L., Clardy, J.
Deposit date:2013-11-18
Release date:2014-02-05
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Atomic structure of the Immunophilin FKBP13-FK506 Complex: Insights into the Composite Binding Surface for Calcineurin
J.Am.Chem.Soc., 116, 1994
4RSD
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STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, ACETATE ION, CHLORIDE ION
Authors:Schultz, L.W., Quirk, D.J., Raines, R.T.
Deposit date:1998-02-05
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
3RSK
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STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, ACETATE ION
Authors:Schultz, L.W., Fisher, B.M., Raines, R.T.
Deposit date:1998-04-09
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A
Biochemistry, 37, 1998
4RSK
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STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A COMPLEXED WITH 3'-UMP
Descriptor:RIBONUCLEASE A, 3'-URIDINEMONOPHOSPHATE
Authors:Schultz, L.W., Fisher, B.M., Raines, R.T.
Deposit date:1998-04-09
Release date:1998-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A
Biochemistry, 37, 1998
1FKG
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DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12
Descriptor:FK506 BINDING PROTEIN, 1,3-DIPHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE
Authors:Holt, D.A., Luengo, J.I., Yamashita, D.S., Oh, H.-J., Konialian, A.L., Yen, H.-K., Rozamus, L.W., Brandt, M., Bossard, M.J., Levy, M.A., Eggleston, D.S., Stout, T.J., Liang, J., Schultz, L.W., Clardy, J.
Deposit date:1993-08-05
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12.
J.Am.Chem.Soc., 115, 1993
1FKH
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DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12
Descriptor:FK506 BINDING PROTEIN, 1-CYCLOHEXYL-3-PHENYL-1-PROPYL-1-(3,3-DIMETHYL-1,2-DIOXYPENTYL)-2-PIPERIDINE CARBOXYLATE
Authors:Holt, D.A., Luengo, J.I., Yamashita, D.S., Oh, H.-J., Konialian, A.L., Yen, H.-K., Rozamus, L.W., Brandt, M., Bossard, M.J., Levy, M.A., Eggleston, D.S., Stout, T.J., Liang, J., Schultz, L.W., Clardy, J.
Deposit date:1993-08-05
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12.
J.Am.Chem.Soc., 115, 1993
1FKI
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DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS, AND THE X-RAY CRYSTAL STRUCTURES OF THEIR COMPLEXES WITH FKBP12
Descriptor:FK506 BINDING PROTEIN, (21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE
Authors:Holt, D.A., Luengo, J.I., Yamashita, D.S., Oh, H.-J., Konialian, A.L., Yen, H.-K., Rozamus, L.W., Brandt, M., Bossard, M.J., Levy, M.A., Eggleston, D.S., Stout, T.J., Liang, J., Schultz, L.W., Clardy, J.
Deposit date:1993-08-05
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:DESIGN, SYNTHESIS, AND KINETIC EVALUATION OF HIGH-AFFINITY FKBP LIGANDS AND THE X-RAY CRYSTAL-STRUCTURES OF THEIR COMPLEXES WITH FKBP12.
J.Am.Chem.Soc., 115, 1993
1C8W
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THR45GLY VARIANT OF RIBONUCLEASE A
Descriptor:PROTEIN (Ribonuclease A), ACETATE ION, CHLORIDE ION
Authors:Kelemen, B.R., Sweeney, R.T., Schultz, L.W., Raines, R.T.
Deposit date:1999-07-30
Release date:2002-05-01
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Excavating an active site: the nucleobase specificity of ribonuclease A.
Biochemistry, 39, 2000
1C9V
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H12A VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, CHLORIDE ION
Authors:Park, C., Schultz, L.W., Raines, R.T.
Deposit date:1999-08-03
Release date:2001-06-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding.
Biochemistry, 40, 2001
1C9X
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H119A VARIANT OF RIBONUCLEASE A
Descriptor:RIBONUCLEASE A, CHLORIDE ION
Authors:Park, C., Schultz, L.W., Raines, R.T.
Deposit date:1999-08-03
Release date:2001-06-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of the active site histidine residues of ribonuclease A to nucleic acid binding.
Biochemistry, 40, 2001
3EE7
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CRYSTAL STRUCTURE OF SARS-COV NSP9 G104E
Descriptor:Replicase polyprotein 1a, PHOSPHATE ION, GLYCEROL
Authors:Miknis, Z.J., Donaldson, E.F., Umland, T.C., Rimmer, R., Baric, R.S., Schultz, L.W.
Deposit date:2008-09-04
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth
J.Virol., 83, 2009
4E4V
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THE CRYSTAL STRUCTURE OF THE DIMERIC HUMAN IMPORTIN ALPHA 1 AT 2.5 ANGSTROM RESOLUTION.
Descriptor:Importin subunit alpha-2, GLYCEROL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Hang, P.C., Miknis, Z.M., Franke, W.A., Umland, T.C., Schultz, L.W.
Deposit date:2012-03-13
Release date:2013-05-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5283 Å)
Cite:The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.
To be Published
4Y0A
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SHIKIMATE KINASE FROM ACINETOBACTER BAUMANNII IN COMPLEX WITH SHIKIMATE
Descriptor:Shikimate kinase, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, SULFATE ION
Authors:Sutton, K.A., Breen, J., MacDonald, U., Beanan, J.M., Olson, R., Russo, T.A., Schultz, L.W., Umland, T.C.
Deposit date:2015-02-05
Release date:2015-08-12
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:Structure of shikimate kinase, an in vivo essential metabolic enzyme in the nosocomial pathogen Acinetobacter baumannii, in complex with shikimate.
Acta Crystallogr.,Sect.D, 71, 2015
5BS5
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EPSP SYNTHASE FROM ACINETOBACTER BAUMANNII
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase
Authors:Sutton, K.A., Schultz, L.W., Russo, T.A., Breen, J., Umland, T.C.
Deposit date:2015-06-01
Release date:2016-02-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:EPSP synthase from Acinetobacter baumannii
Acta Crystallogr.,Sect.F, 2016
5BUF
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2.37 ANGSTROM STRUCTURE OF EPSP SYNTHASE FROM ACINETOBACTER BAUMANNII
Descriptor:3-phosphoshikimate 1-carboxyvinyltransferase, CHLORIDE ION
Authors:Sutton, K.A., Schultz, L.W., Breen, J., Graham, J., Umland, T.C.
Deposit date:2015-06-03
Release date:2016-02-17
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase from the ESKAPE pathogen Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 72, 2016
1F40
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SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A NEUROTROPHIC LIGAND
Descriptor:FK506 BINDING PROTEIN (FKBP12), (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE
Authors:Sich, C., Improta, S., Cowley, D.J., Guenet, C., Merly, J.P., Teufel, M., Saudek, V.
Deposit date:2000-06-07
Release date:2000-11-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamics.
Eur.J.Biochem., 267, 2000
1N3Z
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CRYSTAL STRUCTURE OF THE [S-CARBOXYAMIDOMETHYL-CYS31, S-CARBOXYAMIDOMETHYL-CYS32] MONOMERIC DERIVATIVE OF THE BOVINE SEMINAL RIBONUCLEASE IN THE LIGANDED STATE
Descriptor:Ribonuclease, seminal, 3'-URIDINEMONOPHOSPHATE, ...
Authors:Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L.
Deposit date:2002-10-30
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins, 52, 2003