Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1FQV
DownloadVisualize
BU of 1fqv by Molmil
Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-06
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS2
DownloadVisualize
BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS1
DownloadVisualize
BU of 1fs1 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
8QYN
DownloadVisualize
BU of 8qyn by Molmil
Human 20S proteasome assembly intermediate structure 5
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYO
DownloadVisualize
BU of 8qyo by Molmil
Human proteasome 20S core particle
Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYL
DownloadVisualize
BU of 8qyl by Molmil
Human 20S proteasome assembly intermediate structure 2
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYM
DownloadVisualize
BU of 8qym by Molmil
Human 20S proteasome assembly intermediate structure 3
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QZ9
DownloadVisualize
BU of 8qz9 by Molmil
Human 20S proteasome assembly intermediate structure 4
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYS
DownloadVisualize
BU of 8qys by Molmil
Human preholo proteasome 20S core particle
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYJ
DownloadVisualize
BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
3IVQ
DownloadVisualize
BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
Descriptor: CiSBC2, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVV
DownloadVisualize
BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
Descriptor: PucSBC1, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVB
DownloadVisualize
BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
Descriptor: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-08-31
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure 9
To be Published
7WUG
DownloadVisualize
BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
Descriptor: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
Authors:Qiao, S, Cheng, J.D, Schulman, B.A.
Deposit date:2022-02-08
Release date:2022-06-08
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
7Z8B
DownloadVisualize
BU of 7z8b by Molmil
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
Descriptor: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ...
Authors:Hopf, L.V.M, Schulman, B.A.
Deposit date:2022-03-17
Release date:2022-08-24
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Nat.Struct.Mol.Biol., 29, 2022
7Z8T
DownloadVisualize
BU of 7z8t by Molmil
CAND1-SCF-SKP2 CAND1 engaged SCF rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8R
DownloadVisualize
BU of 7z8r by Molmil
CAND1-CUL1-RBX1
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7ZBZ
DownloadVisualize
BU of 7zbz by Molmil
CAND1 delhairpin-SCF-SKP2 CAND1 partly engaged SCF partly rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-24
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8V
DownloadVisualize
BU of 7z8v by Molmil
CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7ZBW
DownloadVisualize
BU of 7zbw by Molmil
CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-24
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
8OIF
DownloadVisualize
BU of 8oif by Molmil
Structure of the UBE1L activating enzyme bound to ISG15 and UBE2L6
Descriptor: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ...
Authors:Wallace, I, Kheewoong, B, Prabu, J.R, Vollrath, R, von Gronau, S, Schulman, B.A, Swatek, K.N.
Deposit date:2023-03-22
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.
Nat Commun, 14, 2023
8PDA
DownloadVisualize
BU of 8pda by Molmil
cryo-EM structure of Doa10 with RING domain in MSP1E3D1
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
Authors:Botsch, J.J, Braeuning, B, Schulman, B.A.
Deposit date:2023-06-12
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8PD0
DownloadVisualize
BU of 8pd0 by Molmil
cryo-EM structure of Doa10 in MSP1E3D1
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
Authors:Botsch, J.J, Braeuning, B, Schulman, B.A.
Deposit date:2023-06-11
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8PJN
DownloadVisualize
BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Descriptor: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-23
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8PMQ
DownloadVisualize
BU of 8pmq by Molmil
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Descriptor: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-29
Release date:2024-01-03
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon