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1FQV
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BU of 1fqv by Molmil
Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-06
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS2
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BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: SKP1, SKP2
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS1
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BU of 1fs1 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
Descriptor: CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45
Authors:Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
Deposit date:2000-09-08
Release date:2000-11-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
8QYN
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BU of 8qyn by Molmil
Human 20S proteasome assembly intermediate structure 5
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYO
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BU of 8qyo by Molmil
Human proteasome 20S core particle
Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYL
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BU of 8qyl by Molmil
Human 20S proteasome assembly intermediate structure 2
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYM
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BU of 8qym by Molmil
Human 20S proteasome assembly intermediate structure 3
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QZ9
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BU of 8qz9 by Molmil
Human 20S proteasome assembly intermediate structure 4
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYS
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BU of 8qys by Molmil
Human preholo proteasome 20S core particle
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
8QYJ
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BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
Descriptor: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
Authors:Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Biorxiv, 2024
3IVQ
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BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
Descriptor: CiSBC2, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVV
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BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
Descriptor: PucSBC1, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
Descriptor: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-08-31
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure 9
To be Published
7WUG
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BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
Descriptor: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
Authors:Qiao, S, Cheng, J.D, Schulman, B.A.
Deposit date:2022-02-08
Release date:2022-06-08
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
7QQY
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BU of 7qqy by Molmil
yeast Gid10 bound to Art2 Pro/N-degron
Descriptor: CHLORIDE ION, ECM21, Uncharacterized protein YGR066C
Authors:Chrustowicz, J, Sherpa, D, Schulman, B.A.
Deposit date:2022-01-10
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters.
Embo Rep., 23, 2022
4F52
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BU of 4f52 by Molmil
Structure of a Glomulin-RBX1-CUL1 complex
Descriptor: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
Authors:Duda, D.M, Olszewski, J.L, Schulman, B.A.
Deposit date:2012-05-11
Release date:2012-09-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
5L9U
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BU of 5l9u by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
Deposit date:2016-06-11
Release date:2016-09-14
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
Deposit date:2016-06-11
Release date:2016-10-26
Last modified:2016-11-02
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
6WY6
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BU of 6wy6 by Molmil
Crystal structure of S. cerevisiae Atg8 in complex with Ede1 (1220-1247)
Descriptor: Autophagy-related protein 8, EH domain-containing and endocytosis protein 1
Authors:Zheng, Y, Wilfling, F, Baumeister, W, Schulman, B.A.
Deposit date:2020-05-12
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits.
Mol.Cell, 80, 2020
4RG6
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BU of 4rg6 by Molmil
Crystal structure of APC3-APC16 complex
Descriptor: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
Authors:Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
Deposit date:2014-09-29
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG9
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BU of 4rg9 by Molmil
Crystal structure of APC3-APC16 complex (Selenomethionine Derivative)
Descriptor: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
Authors:Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
Deposit date:2014-09-29
Release date:2014-12-24
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
6SWY
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BU of 6swy by Molmil
Structure of active GID E3 ubiquitin ligase complex minus Gid2 and delta Gid9 RING domain
Descriptor: Glucose-induced degradation protein 8, Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10,Protein FYV10, Vacuolar import and degradation protein 24, ...
Authors:Qiao, S, Prabu, J.R, Schulman, B.A.
Deposit date:2019-09-24
Release date:2019-11-20
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly
Mol.Cell, 77, 2020
6TTU
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BU of 6ttu by Molmil
Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2
Descriptor: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Prabu, J.R, Schulman, B.A.
Deposit date:2019-12-30
Release date:2020-02-12
Last modified:2020-03-04
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
7Z8B
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BU of 7z8b by Molmil
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
Descriptor: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ...
Authors:Hopf, L.V.M, Schulman, B.A.
Deposit date:2022-03-17
Release date:2022-08-24
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Nat.Struct.Mol.Biol., 29, 2022
7Z8T
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BU of 7z8t by Molmil
CAND1-SCF-SKP2 CAND1 engaged SCF rocked
Descriptor: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
Authors:Baek, K, Schulman, B.A.
Deposit date:2022-03-18
Release date:2023-04-19
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023

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PDB entries from 2024-03-13

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