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1N4H
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CHARACTERIZATION OF LIGANDS FOR THE ORPHAN NUCLEAR RECEPTOR RORBETA
Descriptor:Nuclear Receptor ROR-beta, Steroid Receptor Coactivator-1, RETINOIC ACID
Authors:Stehlin-Gaon, C., Willmann, D., Sanglier, S., Van Dorsselaer, A., Renaud, J.-P., Moras, D., Schuele, R.
Deposit date:2002-10-31
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta
Nat.Struct.Biol., 10, 2003
1NQ7
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CHARACTERIZATION OF LIGANDS FOR THE ORPHAN NUCLEAR RECEPTOR RORBETA
Descriptor:NUCLEAR RECEPTOR ROR-BETA, STEROID RECEPTOR COACTIVATOR-1, 7-(3,5-DITERT-BUTYLPHENYL)-3-METHYLOCTA-2,4,6-TRIENOIC ACID
Authors:Stehlin-Gaon, C., Willmann, D., Sanglier, S., Van Dorsselaer, A., Renaud, J.-P., Moras, D., Schuele, R.
Deposit date:2003-01-21
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta
Nat.Struct.Biol., 10, 2003
5AFW
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ASSEMBLY OF METHYLATED LSD1 AND CHD1 DRIVES AR-DEPENDENT TRANSCRIPTION AND TRANSLOCATION
Descriptor:CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, 1,2-ETHANEDIOL, ...
Authors:Metzger, E., Willmann, D., McMillan, J., Petroll, K., Metzger, P., Gerhardt, S., vonMaessenhausen, A., Schott, A.K., Espejo, A., Eberlin, A., Wohlwend, D., Schuele, K.M., Schleicher, M., Perner, S., Bedford, M.T., Dengjel, J., Flaig, R., Einsle, O., Schuele, R.
Deposit date:2015-01-26
Release date:2016-01-13
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Nat.Struct.Mol.Biol., 23, 2016
5ANQ
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INHIBITORS OF JUMONJIC DOMAIN-CONTAINING HISTONE DEMETHYLASES
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4A, 2-{2-[(pyridin-3-ylmethyl)amino]pyrimidin-4-yl}pyridine-4-carboxylic acid, FE (II) ION, ...
Authors:Roatsch, M., Robaa, D., Pippel, M., Nettleship, J.E., Reddivari, Y., Bird, L.E., Hoffmann, I., Franz, H., Owens, R.J., Schuele, R., Flaig, R., Sippl, W., Jung, M.
Deposit date:2015-09-07
Release date:2016-03-23
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substituted 2-(2-Aminopyrimidin-4-Yl)Pyridine-4-Carboxylates as Potent Inhibitors of Jumonjic Domain-Containing Histone Demethylases.
Fut.Med.Chem., 8, 2016
1K4W
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X-RAY STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR ROR BETA LIGAND-BINDING DOMAIN IN THE ACTIVE CONFORMATION
Descriptor:Nuclear receptor ROR-beta, steroid receptor coactivator-1, STEARIC ACID
Authors:Stehlin, C., Wurtz, J.M., Steinmetz, A., Greiner, E., Schuele, R., Moras, D., Renaud, J.P.
Deposit date:2001-10-09
Release date:2002-04-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
EMBO J., 20, 2001
1KV6
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X-RAY STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR ERR3 LIGAND-BINDING DOMAIN IN THE CONSTITUTIVELY ACTIVE CONFORMATION
Descriptor:ESTROGEN-RELATED RECEPTOR GAMMA, steroid receptor coactivator 1
Authors:Greschik, H., Wurtz, J.-M., Sanglier, S., Bourguet, W., van Dorsselaer, A., Moras, D., Renaud, J.-P., Structural Proteomics in Europe (SPINE)
Deposit date:2002-01-25
Release date:2003-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3
Mol.Cell, 9, 2002