Author results

1A50
  • Download 1a50
  • View 1a50
Molmil generated image of 1a50
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE
Descriptor:TRYPTOPHAN SYNTHASE (ALPHA CHAIN), TRYPTOPHAN SYNTHASE (BETA CHAIN), 5-FLUOROINDOLE PROPANOL PHOSPHATE, ...
Authors:Schneider, T.R., Gerhardt, E., Lee, M., Liang, P.-H., Anderson, K.S., Schlichting, I.
Deposit date:1998-02-18
Release date:1999-03-30
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop closure and intersubunit communication in tryptophan synthase.
Biochemistry, 37, 1998
1A5S
  • Download 1a5s
  • View 1a5s
Molmil generated image of 1a5s
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE AND L-SER BOUND AS AMINO ACRYLATE TO THE BETA SITE
Descriptor:TRYPTOPHAN SYNTHASE (ALPHA CHAIN), TRYPTOPHAN SYNTHASE (BETA CHAIN), 5-FLUOROINDOLE PROPANOL PHOSPHATE, ...
Authors:Schneider, T.R., Gerhardt, E., Lee, M., Liang, P.-H., Anderson, K.S., Schlichting, I.
Deposit date:1998-02-17
Release date:1999-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop closure and intersubunit communication in tryptophan synthase.
Biochemistry, 37, 1998
1QOW
  • Download 1qow
  • View 1qow
Molmil generated image of 1qow
MERSACIDIN FROM BACILLUS
Descriptor:MERSACIDIN, METHANOL
Authors:Schneider, T.R., Kaercher, J., Sheldrick, G.M.
Deposit date:1999-11-19
Release date:2000-05-26
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Ab initio structure determination of the lantibiotic mersacidin.
Acta Crystallogr.,Sect.D, 56, 2000
2WSY
  • Download 2wsy
  • View 2wsy
Molmil generated image of 2wsy
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE
Descriptor:TRYPTOPHAN SYNTHASE, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Schneider, T.R., Gerhardt, E., Lee, M., Liang, P.-H., Anderson, K.S., Schlichting, I.
Deposit date:1998-02-18
Release date:1999-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Loop closure and intersubunit communication in tryptophan synthase.
Biochemistry, 37, 1998
1HFB
  • Download 1hfb
  • View 1hfb
Molmil generated image of 1hfb
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHOSPHOENOLPYRUVATE
Descriptor:TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE, PHOSPHOENOLPYRUVATE
Authors:Schneider, T.R., Hartmann, M., Braus, G.H.
Deposit date:2000-11-30
Release date:2003-01-14
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of Feedback-Inhibited Beta /Alpha Barrel Isoenzymes by Gene Duplication and a Single Mutation
Proc.Natl.Acad.Sci.USA, 100, 2003
1OF6
  • Download 1of6
  • View 1of6
Molmil generated image of 1of6
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH TYROSINE AND MANGANESE
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED, MANGANESE (II) ION, ...
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G., Schneider, T.R.
Deposit date:2003-04-08
Release date:2004-05-06
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Double Complex of the Tyrosine Sensitive Dahp Synthase from Yeast
To be Published
1OF8
  • Download 1of8
  • View 1of8
Molmil generated image of 1of8
DOUBLE COMPLEX OF THE TYROSINE SENSITIVE DAHP SYNTHASE FROM S. CEREVISIAE WITH CO2+, PEP AND THE E4P ANALOGOUE G3P
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED, COBALT (II) ION, ...
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-08
Release date:2004-04-08
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1OFA
  • Download 1ofa
  • View 1ofa
Molmil generated image of 1ofa
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH PHOSPHOENOLPYRUVATE AND COBALT(II)
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, COBALT (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-09
Release date:2004-04-08
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1OG0
  • Download 1og0
  • View 1og0
Molmil generated image of 1og0
CRYSTAL STRUCTURE OF THE MUTANT G226S OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE
Descriptor:Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited, MANGANESE (II) ION, ...
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-22
Release date:2004-04-30
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Mutant G226S of the Tyrosine-Regulated 3-Deoxy-D-Arabino-Heptulosonate -7-Phosphate Synthase from Saccharomyces Cerevisiae Complexed with Phenylalanine and Manganese
To be Published
1OFB
  • Download 1ofb
  • View 1ofb
Molmil generated image of 1ofb
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH MANGANESE(II)
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, MANGANESE (II) ION, GLYCEROL
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-09
Release date:2004-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1OFO
  • Download 1ofo
  • View 1ofo
Molmil generated image of 1ofo
CRYSTAL STRUCTURE OF THE TYROSINE REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH 2-PHOSPHOGLYCOLATE
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, 2-PHOSPHOGLYCOLIC ACID
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G., Schneider, T.R.
Deposit date:2003-04-17
Release date:2004-04-15
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism.
J.Mol.Biol., 337, 2004
1OFP
  • Download 1ofp
  • View 1ofp
Molmil generated image of 1ofp
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-17
Release date:2004-04-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1OFQ
  • Download 1ofq
  • View 1ofq
Molmil generated image of 1ofq
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH MANGANESE(II)
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, MANGANESE (II) ION
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-04-17
Release date:2004-04-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1AR2
  • Download 1ar2
  • View 1ar2
Molmil generated image of 1ar2
DISULFIDE-FREE IMMUNOGLOBULIN FRAGMENT
Descriptor:REI
Authors:Uson, I., Bes, M.T., Sheldrick, G.M., Schneider, T.R., Hartsch, T., Fritz, H.-J.
Deposit date:1997-08-08
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray crystallography reveals stringent conservation of protein fold after removal of the only disulfide bridge from a stabilized immunoglobulin variable domain.
Structure Fold.Des., 2, 1997
1BWW
  • Download 1bww
  • View 1bww
Molmil generated image of 1bww
BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT
Descriptor:PROTEIN (IG KAPPA CHAIN V-I REGION REI)
Authors:Uson, I., Pohl, E., Schneider, T.R., Dauter, Z., Schmidt, A., Fritz, H.J., Sheldrick, G.M.
Deposit date:1998-09-29
Release date:1998-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints.
Acta Crystallogr.,Sect.D, 55, 1999
1GL2
  • Download 1gl2
  • View 1gl2
Molmil generated image of 1gl2
CRYSTAL STRUCTURE OF AN ENDOSOMAL SNARE CORE COMPLEX
Descriptor:ENDOBREVIN, SYNTAXIN 7, VESICLE TRANSPORT V-SNARE PROTEIN VTI1-LIKE 1, ...
Authors:Antonin, W., Becker, S., Jahn, R., Schneider, T.R.
Deposit date:2001-08-22
Release date:2002-01-15
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Endosomal Snare Complex Reveals Common Structural Principles of All Snares.
Nat.Struct.Biol., 9, 2001
1HAX
  • Download 1hax
  • View 1hax
Molmil generated image of 1hax
SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (A) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 AT PH 5
Descriptor:BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ...
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1HAY
  • Download 1hay
  • View 1hay
Molmil generated image of 1hay
SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (B) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 JUMPED TO PH 10 FOR 10 SECONDS
Descriptor:ELASTASE 1, CALCIUM ION, SULFATE ION
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1HAZ
  • Download 1haz
  • View 1haz
Molmil generated image of 1haz
SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (C) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 JUMPED TO PH 9 FOR 1 MINUTE
Descriptor:BETA-CASOMORPHIN-7, ELASTASE 1, CALCIUM ION, ...
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1HB0
  • Download 1hb0
  • View 1hb0
Molmil generated image of 1hb0
SNAPSHOTS OF SERINE PROTEASE CATALYSIS: (D) ACYL-ENZYME INTERMEDIATE BETWEEN PORCINE PANCREATIC ELASTASE AND HUMAN BETA-CASOMORPHIN-7 JUMPED TO PH 10 FOR 2 MINUTES
Descriptor:ELASTASE 1, CALCIUM ION, SULFATE ION
Authors:Wilmouth, R.C., Edman, K., Neutze, R., Wright, P.A., Clifton, I.J., Schneider, T.R., Schofield, C.J., Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
1L2H
  • Download 1l2h
  • View 1l2h
Molmil generated image of 1l2h
CRYSTAL STRUCTURE OF INTERLEUKIN 1-BETA F42W/W120F MUTANT
Descriptor:Interleukin 1-beta
Authors:Rudolph, M.G., Kelker, M.S., Schneider, T.R., Yeates, T.O., Oseroff, V., Heidary, D.K., Jennings, P.A., Wilson, I.A.
Deposit date:2002-02-21
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta.
Acta Crystallogr.,Sect.D, 59, 2003
1OAB
  • Download 1oab
  • View 1oab
Molmil generated image of 1oab
CRYSTAL STRUCTURE OF THE TYROSINE REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH PHOSPHOENOLPYRUVATE AND MANGANESE(II)
Descriptor:TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G.H., Schneider, T.R.
Deposit date:2003-01-06
Release date:2004-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
J.Mol.Biol., 337, 2004
1OFR
  • Download 1ofr
  • View 1ofr
Molmil generated image of 1ofr
CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE
Descriptor:PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, MANGANESE (II) ION, PHENYLALANINE
Authors:Koenig, V., Pfeil, A., Heinrich, G., Braus, G., Schneider, T.R.
Deposit date:2003-04-18
Release date:2004-04-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism.
J.Mol.Biol., 337, 2004
1OK0
  • Download 1ok0
  • View 1ok0
Molmil generated image of 1ok0
CRYSTAL STRUCTURE OF TENDAMISTAT
Descriptor:ALPHA-AMYLASE INHIBITOR HOE-467A, GLYCEROL, CHLORIDE ION
Authors:Koenig, V., Vertesy, L., Schneider, T.R.
Deposit date:2003-07-16
Release date:2004-01-15
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Crystal Structure of the Alpha-Amylase Inhibitor Tendamistat at 0.93 A
Acta Crystallogr.,Sect.D, 59, 2003
1PWL
  • Download 1pwl
  • View 1pwl
Molmil generated image of 1pwl
CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND MINALRESTAT
Descriptor:aldose reductase, 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:El-Kabbani, O., Darmanin, C., Schneider, T.R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A., Podjarny, A.
Deposit date:2003-07-02
Release date:2004-02-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors
PROTEINS, 55, 2004