Author results

3KOF
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CRYSTAL STRUCTURE OF THE DOUBLE MUTANT F178Y/R181E OF E.COLI TRANSALDOLASE B
Descriptor:Transaldolase B, SULFATE ION
Authors:Schneider, S., Gutierrez, M., Sandalova, T., Schneider, G., Clapes, P., Sprenger, G.A., Samland, A.K.
Deposit date:2009-11-13
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Redesigning the Active Site of Transaldolase TalB from Escherichia coli: New Variants with Improved Affinity towards Nonphosphorylated Substrates.
Chembiochem, 11, 2010
2J0P
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STRUCTURE OF THE HAEM-CHAPERONE PROTEOBACTERIA-PROTEIN HEMS
Descriptor:HEMIN TRANSPORT PROTEIN HEMS, PROTOPORPHYRIN IX CONTAINING FE, DODECAETHYLENE GLYCOL, ...
Authors:Schneider, S., Sharp, K.H., Barker, P.D., Paoli, M.
Deposit date:2006-08-04
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An Induced Fit Conformational Change Underlies the Binding Mechanism of the Heme Transport Proteobacteria-Protein Hems.
J.Biol.Chem., 281, 2006
2J0R
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STRUCTURE OF THE HAEM-CHAPERONE PROTEOBACTERIA-PROTEIN HEMS
Descriptor:HEMIN TRANSPORT PROTEIN HEMS, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Schneider, S., Sharp, K.H., Barker, P.D., Paoli, M.
Deposit date:2006-08-04
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An Induced Fit Conformational Change Underlies the Binding Mechanism of the Heme Transport Proteobacteria-Protein Hems.
J.Biol.Chem., 281, 2006
2V79
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF DNAD FROM BACILLUS SUBTILIS
Descriptor:DNA REPLICATION PROTEIN DNAD, SODIUM ION, CHLORIDE ION
Authors:Schneider, S., Zhang, W., Soultanas, P., Paoli, M.
Deposit date:2007-07-27
Release date:2008-01-15
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the N-Terminal Oligomerization Domain of Dnad Reveals a Unique Tetramerization Motif and Provides Insights Into Scaffold Formation.
J.Mol.Biol., 376, 2008
4BW9
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PYLRS Y306G, Y384F, I405R MUTANT IN COMPLEX WITH AMP-PNP
Descriptor:PYRROLYSINE--TRNA LIGASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Schneider, S., Vrabel, M., Gattner, M.J., Fluegel, V., Lopez-Carillo, V., Carell, T.
Deposit date:2013-07-01
Release date:2013-07-31
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Insights Into Incorporation of Norbornene Amino Acids for Click Modification of Proteins
Chem.Bio.Chem., 14, 2013
4BWA
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PYLRS Y306G, Y384F, I405R MUTANT IN COMPLEX WITH ADENYLATED NORBORNENE
Descriptor:PYRROLYSINE--TRNA LIGASE, MAGNESIUM ION, Adenylated Norbornene, ...
Authors:Schneider, S., Vrabel, M., Gattner, M.J., Fluegel, V., Lopez-Carillo, V., Carell, T.
Deposit date:2013-07-01
Release date:2013-07-31
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Insights Into Incorporation of Norbornene Amino Acids for Click Modification of Proteins
Chem.Bio.Chem., 14, 2013
5LBT
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STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH IMIQUIMOD
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Schneider, S., Gross, O.
Deposit date:2016-06-17
Release date:2016-07-27
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Imiquimod Inhibits Mitochondrial Complex I and Induces K+ efflux-independent Nlrp3 Inflammasome Activation via Nek7
To Be Published
5LBU
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STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH TO CL097
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Schneider, S., Gross, O.
Deposit date:2016-06-17
Release date:2016-07-27
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Imiquimod Inhibits Mitochondrial Complex I and Induces K+ efflux-independent Nlrp3 Inflammasome Activation via Nek7
To Be Published
5LBW
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STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH VOLITINIB
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Schneider, S., Medard, G., Kuester, B.
Deposit date:2016-06-17
Release date:2017-11-29
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The target landscape of clinical kinase drugs.
Science, 358, 2017
5LBY
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STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH CRENOLANIB
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Schneider, S., Medard, G., Kuester, B.
Deposit date:2016-06-17
Release date:2017-11-29
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The target landscape of clinical kinase drugs.
Science, 358, 2017
5LBZ
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STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH PACRITINIB
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], FLAVIN-ADENINE DINUCLEOTIDE, 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene, ...
Authors:Schneider, S., Medard, G., Kuster, B.
Deposit date:2016-06-17
Release date:2017-11-29
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The target landscape of clinical kinase drugs.
Science, 358, 2017
2XGQ
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STRUCTURE OF YEAST DNA POLYMERASE ETA IN COMPLEX WITH C8-N-ACETYL-2- AMINOANTHRACENE CONTAINING DNA
Descriptor:DNA POLYMERASE ETA, 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', 5'-D(*CP*8AG*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', ...
Authors:Schneider, S., Schorr, S., Carell, T.
Deposit date:2010-06-07
Release date:2010-11-03
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.
Proc.Natl.Acad.Sci.USA, 107, 2010
5G5S
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STRUCTURE OF THE ARGONAUTE PROTEIN FROM METHANOCALDCOCCUS JANASCHII
Descriptor:ARGONAUTE, MAGNESIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Schneider, S., Oellig, C.A., Keegan, R., Grohmann, D., Zander, A., Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
5G5T
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STRUCTURE OF THE ARGONAUTE PROTEIN FROM METHANOCALDCOCCUS JANASCHII IN COMPLEX WITH GUIDE DNA
Descriptor:ARGONAUTE, GUIDE DNA, MAGNESIUM ION, ...
Authors:Schneider, S., Oellig, C.A., Keegan, R., Grohmann, D., Zander, A., Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
5JM0
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STRUCTURE OF THE S. CEREVISIAE ALPHA-MANNOSIDASE 1
Descriptor:Alpha-mannosidase,Alpha-mannosidase,Alpha-mannosidase
Authors:Schneider, S., Kosinski, J., Jakobi, A.J., Hagen, W.J.H., Sachse, C.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.
Embo Rep., 17, 2016
4CIS
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STRUCTURE OF MUTM IN COMPLEX WITH CARBOCYCLIC 8-OXO-G CONTAINING DNA
Descriptor:FORMAMIDOPYRIMIDIN DNA GLYCOSYLASE, DNA, ZINC ION, ...
Authors:Schneider, S., Sadeghian, K., Flaig, D., Blank, I.D., Strasser, R., Stathis, D., Winnacker, M., Carell, T., Ochsenfeld, C.
Deposit date:2013-12-15
Release date:2014-06-04
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Ribose-protonated DNA base excision repair: a combined theoretical and experimental study.
Angew. Chem. Int. Ed. Engl., 53, 2014
5G32
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STRUCTURE OF RAD14 IN COMPLEX WITH ACETYLAMINOPHENYL-GUANINE CONTAINING DNA
Descriptor:RAD14, 5'-D(*GP*CP*TP*CP*TP*AP*6FKP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', ...
Authors:Simon, N., Ebert, C., Schneider, S.
Deposit date:2016-04-18
Release date:2016-06-01
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
5G33
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STRUCTURE OF RAD14 IN COMPLEX WITH ACETYLNAPHTYL-GUANINE CONTAINING DNA
Descriptor:RAD14, 5'-D(*GP*CP*TP*CP*TP*AP*MFOP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', ...
Authors:Simon, N., Ebert, C., Schneider, S.
Deposit date:2016-04-18
Release date:2016-06-01
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
5G34
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STRUCTURE OF RAD14 IN COMPLEX WITH ACETYLAMINOANTHRACENE-C8-GUANINE CONTAINING DNA
Descriptor:RAD14, 5'-D(*GP*CP*TP*CP*TP*AP*6FKP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', ...
Authors:Simon, N., Ebert, C., Schneider, S.
Deposit date:2016-04-18
Release date:2016-06-01
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
5G35
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STRUCTURE OF RAD14 IN COMPLEX WITH ACETYLAMINOPYREN-C8-GUANINE CONTAINING DNA
Descriptor:RAD14, 5'-D(*GP*CP*TP*CP*TP*AP*8PYP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', ...
Authors:Simon, N., Ebert, C., Schneider, S.
Deposit date:2016-04-18
Release date:2016-06-01
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
5LCL
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STRUCTURE OF THE RAD14 DNA-BINDING DOMAIN IN COMPLEX WITH C8-AMINOFLUORENE- GUANINE CONTAINING DNA
Descriptor:DNA repair protein RAD14, GCTCTAC(8AF)TCATCA, DNA (5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*G)-3'), ...
Authors:Schneider, S., Carell, T., Ebert, C., Simon, N.
Deposit date:2016-06-22
Release date:2017-05-10
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Recognition of N(2) -Aryl- and C8-Aryl DNA Lesions by the Repair Protein XPA/Rad14.
Chembiochem, 18, 2017
5LCM
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STRUCTURE OF THE RAD14 DNA-BINDING DOMAIN IN COMPLEX WITH N2-ACETYLAMINONAPHTYL- GUANINE CONTAINING DNA
Descriptor:DNA repair protein RAD14, DNA (5'-D(*GP*CP*TP*CP*TP*AP*CP*(AAN)P*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*G)-3'), ...
Authors:Schneider, S., Ebert, C., Simon, N., Carell, T.
Deposit date:2016-06-22
Release date:2017-05-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Recognition of N(2) -Aryl- and C8-Aryl DNA Lesions by the Repair Protein XPA/Rad14.
Chembiochem, 18, 2017
5LIR
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STRUCTURE OF THE SALTY SIGMA CROSS-REACTING PROTEIN 27A (SCRP-27A) FROM SALMONELLA TYPHIMURIUM
Descriptor:Sigma cross-reacting protein 27A (SCRP-27A), DI(HYDROXYETHYL)ETHER
Authors:Schneider, S., Mandel, M., Sieber, S.A.
Deposit date:2016-07-15
Release date:2016-09-14
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Natural-Product-Inspired Aminoepoxybenzoquinones Kill Members of the Gram-Negative Pathogen Salmonella by Attenuating Cellular Stress Response.
Angew.Chem.Int.Ed.Engl., 55, 2016
2WB2
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DROSOPHILA MELANOGASTER (6-4) PHOTOLYASE BOUND TO DOUBLE STRANDED DNA CONTAINING A T(6-4)C PHOTOLESION
Descriptor:PHOTOLYASE, 5'-D(*AP*CP*AP*GP*CP*GP*GP*64PP*ZP*GP*CP*AP *GP*GP*T)-3', 5'-D(*TP*AP*CP*CP*TP*GP*CP*GP*AP*CP*CP*GP*CP*TP*G)-3', ...
Authors:Glas, A.F., Schneider, S., Maul, M.J., Hennecke, U., Carell, T.
Deposit date:2009-02-20
Release date:2009-03-17
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of Uv- Induced (6-4) and Dewar Photolesions.
Chemistry, 15, 2009
2WTF
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DNA POLYMERASE ETA IN COMPLEX WITH THE CIS-DIAMMINEPLATINUM (II) 1,3- GTG INTRASTRAND CROSS-LINK
Descriptor:DNA POLYMERASE ETA, 5'-D(*TP*CP*TP*TP*CP*TP*GP*TP*GP*CP *TP*CP*AP*CP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*GP*TP*GP*AP*GP*CP)-3', ...
Authors:Reissner, T., Schneider, S., Ziv, O., Schorr, S., Livneh, Z., Carell, T.
Deposit date:2009-09-16
Release date:2010-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Cisplatin-(1,3-Gtg) Cross-Link within DNA Polymerase Eta.
Angew.Chem.Int.Ed.Engl., 49, 2010