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2X7O
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CRYSTAL STRUCTURE OF TGFBRI COMPLEXED WITH AN INDOLINONE INHIBITOR
Descriptor:TGF-BETA RECEPTOR TYPE I, (3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]AMINO}METHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-6-CARBOXAMIDE
Authors:Roth, G.J., Heckel, A., Brandl, T., Grauert, M., Hoerer, S., Kley, J.T., Schnapp, G., Baum, P., Mennerich, D., Schnapp, A., Park, J.E.
Deposit date:2010-03-03
Release date:2010-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri)
J.Med.Chem., 53, 2010
3P0G
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STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE BETA2 ADRENOCEPTOR
Descriptor:Beta-2 adrenergic receptor, Lysozyme, Camelid Antibody Fragment, ...
Authors:Rasmussen, S.G.F., Choi, H.-J., Fung, J.J., Pardon, E., Casarosa, P., Chae, P.S., DeVree, B.T., Rosenbaum, D.M., Thian, F.S., Kobilka, T.S., Schnapp, A., Konetzki, I., Sunahara, R.K., Gellman, S.H., Pautsch, A., Steyaert, J., Weis, W.I., Kobilka, B.K.
Deposit date:2010-09-28
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011