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2KMS
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COMBINED HIGH- AND LOW-RESOLUTION TECHNIQUES REVEAL COMPACT STRUCTURE IN CENTRAL PORTION OF FACTOR H DESPITE LONG INTER-MODULAR LINKERS
Descriptor:Complement factor H
Authors:Schmidt, C.Q., Herbert, A.P., Guariento, M., Mertens, H.D.T., Soares, D.C., Uhrin, D., Rowe, A.J., Svergun, D.I., Barlow, P.N.
Deposit date:2009-08-04
Release date:2009-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module
J.Mol.Biol., 395, 2010
2JGW
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STRUCTURE OF CCP MODULE 7 OF COMPLEMENT FACTOR H - THE AMD AT RISK VARIENT (402H)
Descriptor:COMPLEMENT FACTOR H
Authors:Herbert, A.P., Deakin, J.A., Schmidt, C.Q., Blaum, B.S., Egan, C., Ferreira, V.P., Pangburn, M.K., Lyon, M., Uhrin, D., Barlow, P.N.
Deposit date:2007-02-16
Release date:2007-03-20
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2JGX
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STRUCTURE OF CCP MODULE 7 OF COMPLEMENT FACTOR H - THE AMD NOT AT RISK VARIENT (402Y)
Descriptor:COMPLEMENT FACTOR H
Authors:Herbert, A.P., Deakin, J.A., Schmidt, C.Q., Blaum, B.S., Egan, C., Ferreira, V.P., Pangburn, M.K., Lyon, M., Uhrin, D., Barlow, P.N.
Deposit date:2007-02-16
Release date:2007-03-20
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2MCY
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CR1 SUSHI DOMAINS 2 AND 3
Descriptor:Complement receptor type 1
Authors:Park, H.J., Guariento, M.J., Maciejewski, M., Hauart, R., Tham, W., Cowman, A.F., Schmidt, C.Q., Martens, H., Liszewski, K.M., Hourcade, D., Barlow, P.N., Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2014-01-22
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCZ
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CR1 SUSHI DOMAINS 1 AND 2
Descriptor:Complement receptor type 1
Authors:Park, H.J., Guariento, M.J., Maciejewski, M., Hauart, R., Tham, W., Cowman, A.F., Schmidt, C.Q., Martens, H., Liszewski, K.M., Hourcade, D., Barlow, P.N., Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2014-01-22
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
3OXU
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COMPLEMENT COMPONENTS FACTOR H CCP19-20 AND C3D IN COMPLEX
Descriptor:Complement C3, HF protein, GLYCEROL
Authors:Morgan, H.P., Schmidt, C.Q., Guariento, M., Gillespie, D., Herbert, A.P., Mertens, H., Blaum, B.S., Svergun, D., Johansson, C.M., Uhrin, D., Barlow, P.N., Hannan, J.P.
Deposit date:2010-09-22
Release date:2011-02-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for engagement by complement factor H of C3b on a self surface.
Nat.Struct.Mol.Biol., 18, 2011
3SW0
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STRUCTURE OF THE C-TERMINAL REGION (MODULES 18-20) OF COMPLEMENT REGULATOR FACTOR H
Descriptor:Complement factor H, GLYCEROL, PHOSPHATE ION
Authors:Morgan, H.P., Guariento, M., Schmidt, C.Q., Barlow, P.N., Hannan, J.P.
Deposit date:2011-07-13
Release date:2012-03-14
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
Plos One, 7, 2012
4B2R
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SOLUTION STRUCTURE OF CCP MODULES 10-11 OF COMPLEMENT FACTOR H
Descriptor:COMPLEMENT FACTOR H
Authors:Makou, E., Mertens, H.D.T., Maciejewski, M., Soares, D.C., Matis, I., Schmidt, C.Q., Herbert, A.P., Svergun, D.I., Barlow, P.N.
Deposit date:2012-07-17
Release date:2012-10-10
Last modified:2016-11-30
Method:SOLUTION NMR
Cite:Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
4B2S
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SOLUTION STRUCTURE OF CCP MODULES 11-12 OF COMPLEMENT FACTOR H
Descriptor:COMPLEMENT FACTOR H
Authors:Makou, E., Mertens, H.D., Maciejewski, M., Soares, D.C., Matis, I., Schmidt, C.Q., Herbert, A.P., Svergun, D.I., Barlow, P.N.
Deposit date:2012-07-17
Release date:2012-10-17
Last modified:2013-05-08
Method:SOLUTION NMR
Cite:Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H.
J.Mol.Biol., 424, 2012
5O32
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THE STRUCTURE OF COMPLEMENT COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, Complement factor I, ...
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (4.206209 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5O35
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STRUCTURE OF COMPLEMENT PROTEINS COMPLEX
Descriptor:Complement C3, Complement factor H,Complement factor H, N-ACETYL-D-GLUCOSAMINE
Authors:Xue, X., Wu, J., Forneris, F., Gros, P.
Deposit date:2017-05-23
Release date:2017-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
5W53
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CRYSTAL STRUCTURE OF THE ERYTHROCYTE-BINDING DOMAIN FROM PLASMODIUM VIVAX RETICULOCYTE-BINDING PROTEIN 2B (PVRBP2B)
Descriptor:Reticulocyte binding protein 2, putative, THIOCYANATE ION, ...
Authors:Gruszczyk, J., Tham, W.H.
Deposit date:2017-06-13
Release date:2017-11-29
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.
Science, 359, 2018