1FKA | | STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Schluenzen, F., Tocilj, A., Zarivach, R., Harms, J., Gluehmann, M., Janell, D., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., Yonath, A. | | Deposit date: | 2000-08-09 | | Release date: | 2000-09-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Cell(Cambridge,Mass.), 102, 2000
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1XBP | | INHIBITION OF PEPTIDE BOND FORMATION BY PLEUROMUTILINS: THE STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH TIAMULIN | | Descriptor: | 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, 50S ribosomal protein L2, ... | | Authors: | Schluenzen, F., Pyetan, E., Fucini, P., Yonath, A., Harms, J.M. | | Deposit date: | 2004-08-31 | | Release date: | 2005-03-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Mol.Microbiol., 54, 2004
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2HHH | | CRYSTAL STRUCTURE OF KASUGAMYCIN BOUND TO THE 30S RIBOSOMAL SUBUNIT | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Schluenzen, F. | | Deposit date: | 2006-06-28 | | Release date: | 2006-09-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Nat.Struct.Mol.Biol., 13, 2006
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1NKW | | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Harms, J.M., Schluenzen, F., Zarivach, R., Bashan, A., Gat, S., Agmon, I., Bartels, H., Franceschi, F., Yonath, A. | | Deposit date: | 2003-01-05 | | Release date: | 2003-02-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | High resolution structure of the large ribosomal subunit from a mesophilic eubacterium
Cell(Cambridge,Mass.), 107, 2001
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6YZ6 | | STRUCTURE OF THE HEMIACETAL COMPLEX BETWEEN THE SARS-COV-2 MAIN PROTEASE AND LEUPEPTIN | | Descriptor: | Main Protease, LEUPEPTIN, DIMETHYL SULFOXIDE, ... | | Authors: | Guenther, S., Reinke, P.Y.A., Oberthuer, D., Yefanov, O., Gelisio, L., Ginn, H.M., Lieske, J., Domaracky, M., Brehm, W., Rahmani Mashhour, A., White, T.A., Knoska, J., Pena Esperanza, G., Koua, F., Tolstikova, A., Groessler, M., Fischer, P., Hennicke, V., Fleckenstein, H., Trost, F., Galchenkova, M., Gevorkov, Y., Li, C., Awel, S., Xavier, P.L., Ullah, N., Andaleeb, H., Falke, S., Alves Franca, B., Schwinzer, M., Brognaro, H., Werner, N., Perbandt, M., Tidow, H., Seychell, B., Beck, T., Meier, S., Zaitsev-Doyle, J.J., Rogers, C., Gieseler, H., Melo, D., Monteiro, D.C.F., Dunkel, I., Lane, T.J., Peck, A., Saouane, S., Hakanpaeae, J., Meyer, J., Noei, H., Gribbon, P., Ellinger, B., Kuzikov, M., Wolf, M., Zhang, L., Ehrt, C., Pletzer-Zelgert, J., Wollenhaupt, J., Feiler, C., Weiss, M., Schluenzen, F., Schulz, E.C., Mehrabi, P., Norton-Baker, B., Schmidt, C., Lorenzen, K., Schubert, R., Sun, X., Han, H., Chari, A., Fernandez Garcia, Y., Turk, D., Hilgenfeld, R., Rarey, M., Zaliani, A., Chapman, H.N., Pearson, A., Betzel, C., Meents, A. | | Deposit date: | 2020-05-06 | | Release date: | 2020-05-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of the hemiacetal complex between the SARS-CoV-2 Main Protease and Leupeptin
To Be Published
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1NJM | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A TRNA ACCEPTOR STEM MIMIC (ASM) AND THE ANTIBIOTIC SPARSOMYCIN | | Descriptor: | 23S ribosomal RNA, tRNA acceptor stem mimic, 50S ribosomal protein L16, ... | | Authors: | Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A. | | Deposit date: | 2003-01-02 | | Release date: | 2003-02-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
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1NJN | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE ANTIBIOTIC SPARSOMYCIN | | Descriptor: | 23S ribosomal RNA, SPARSOMYCIN | | Authors: | Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A. | | Deposit date: | 2003-01-02 | | Release date: | 2003-02-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
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1NJO | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A SHORT SUBSTRATE ANALOG ACCPUROMYCIN (ACCP) | | Descriptor: | 23S ribosomal RNA, RNA ACC(Puromycin) | | Authors: | Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A. | | Deposit date: | 2003-01-02 | | Release date: | 2003-02-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
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1NJP | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A TRNA ACCEPTOR STEM MIMIC (ASM) | | Descriptor: | 23S ribosomal RNA, tRNA acceptor stem mimic, 50S ribosomal protein L16, ... | | Authors: | Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A. | | Deposit date: | 2003-01-02 | | Release date: | 2003-02-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
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1OND | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TROLEANDOMYCIN MACROLIDE ANTIBIOTIC | | Descriptor: | 23S RIBOSOMAL RNA, 50S ribosomal protein L22, 50S ribosomal protein L32, ... | | Authors: | Berisio, R., Schluenzen, F., Harms, J., Bashan, A., Auerbach, T., Baram, D., Yonath, A. | | Deposit date: | 2003-02-27 | | Release date: | 2003-04-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural insight into the role of the ribosomal tunnel in cellular regulation
Nat.Struct.Biol., 10, 2003
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1P9X | | THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC | | Descriptor: | 23S RIBOSOMAL RNA, TELITHROMYCIN | | Authors: | Berisio, R., Harms, J., Schluenzen, F., Zarivach, R., Hansen, H.A., Fucini, P., Yonath, A. | | Deposit date: | 2003-05-13 | | Release date: | 2003-08-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural insight into the antibiotic action of telithromycin against resistant mutants
J.Bacteriol., 185, 2003
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1Y69 | | RRF DOMAIN I IN COMPLEX WITH THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS | | Descriptor: | 23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L16, ... | | Authors: | Wilson, D.N., Schluenzen, F., Harms, J.M., Yoshida, T., Ohkubo, T., Albrecht, R., Buerger, J., Kobayashi, Y., Fucini, P. | | Deposit date: | 2004-12-04 | | Release date: | 2005-03-01 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | X-ray crystallography on ribosome recycling: mechanism of binding and action of RRF on the 50S ribosomal subunit
EMBO J., 24, 2005
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1ZAV | | RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P21 | | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L7/L12 | | Authors: | Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C. | | Deposit date: | 2005-04-07 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
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1ZAW | | RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P212121, FORM A | | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L7/L12 | | Authors: | Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C. | | Deposit date: | 2005-04-07 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
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1ZAX | | RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P212121, FORM B | | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L7/L12 | | Authors: | Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C. | | Deposit date: | 2005-04-07 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
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2E5L | | A SNAPSHOT OF THE 30S RIBOSOMAL SUBUNIT CAPTURING MRNA VIA THE SHINE- DALGARNO INTERACTION | | Descriptor: | 16S ribosomal RNA, 5'-R(*GP*AP*AP*AP*GP*A)-3', 30S ribosomal protein S2, ... | | Authors: | Kaminishi, T., Wilson, D.N., Takemoto, C., Harms, J.M., Kawazoe, M., Schluenzen, F., Hanawa-Suetsugu, K., Shirouzu, M., Fucini, P., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-12-21 | | Release date: | 2007-05-15 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction
Structure, 15, 2007
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2ZJP | | THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS | | Descriptor: | 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-07 | | Release date: | 2008-06-17 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
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2ZJQ | | INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT | | Descriptor: | ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-08 | | Release date: | 2008-06-17 | | Last modified: | 2014-04-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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2ZJR | | REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS | | Descriptor: | ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-08 | | Release date: | 2008-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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3CF5 | | THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS | | Descriptor: | 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ... | | Authors: | Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P. | | Deposit date: | 2008-03-02 | | Release date: | 2008-06-17 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
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3DLL | | THE OXAZOLIDINONE ANTIBIOTICS PERTURB THE RIBOSOMAL PEPTIDYL-TRANSFERASE CENTER AND EFFECT TRNA POSITIONING | | Descriptor: | rRNA-23S ribosomal RNA, rRNA-5S ribosomal RNA, 50S ribosomal protein L2, ... | | Authors: | Wilson, D.N., Schluenzen, F., Harms, J.M., Starosta, A.L., Connell, S.R., Fucini, P. | | Deposit date: | 2008-06-27 | | Release date: | 2008-09-16 | | Last modified: | 2015-07-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
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4V61 | | HOMOLOGY MODEL FOR THE SPINACH CHLOROPLAST 30S SUBUNIT FITTED TO 9.4A CRYO-EM MAP OF THE 70S CHLORORIBOSOME. | | Descriptor: | 16S rRNA, Ribosomal Protein S2, Ribosomal Protein S3, ... | | Authors: | Sharma, M.R., Wilson, D.N., Datta, P.P., Barat, C., Schluenzen, F., Fucini, P., Agrawal, R.K. | | Deposit date: | 2007-11-09 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
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1I94 | | CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3 | | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F. | | Deposit date: | 2001-03-18 | | Release date: | 2001-04-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
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1I95 | | CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH EDEINE | | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F. | | Deposit date: | 2001-03-18 | | Release date: | 2001-04-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
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1I96 | | CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE TRANSLATION INITIATION FACTOR IF3 (C-TERMINAL DOMAIN) | | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F. | | Deposit date: | 2001-03-18 | | Release date: | 2001-04-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
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