1AW7
 
 | | Q136A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1997-10-11 | | Release date: | 1998-10-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
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3EA6
 | | Atomic resolution of crystal structure of SEK | | Descriptor: | IODIDE ION, Staphylococcal enterotoxin K, ZINC ION | | Authors: | Shi, K, Huseby, M, Schlievert, P.M, Ohlendorf, D.H, Earhart, C.A. | | Deposit date: | 2008-08-24 | | Release date: | 2009-06-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (0.92 Å) | | Cite: | Structural Studies of an Emerging Pyrogenic Superantigen, SEK
To be Published
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1TS5
 | | I140T MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1997-10-10 | | Release date: | 1998-12-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
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1TS4
 | | Q139K MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1997-10-10 | | Release date: | 1998-12-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
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1QTF
 | | CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN B | | Descriptor: | EXFOLIATIVE TOXIN B | | Authors: | Vath, G.M, Earhart, C.A, Monie, D.D, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1999-06-27 | | Release date: | 1999-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity.
Biochemistry, 38, 1999
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3HL6
 | | Staphylococcus aureus pathogenicity island 3 ORF9 protein | | Descriptor: | CHLORIDE ION, Pathogenicity island protein | | Authors: | Kruse, A.C, Huseby, M, Shi, K, Digre, J, Schlievert, P.M, Ohlendorf, D.H, Earhart, C.A. | | Deposit date: | 2009-05-26 | | Release date: | 2010-06-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and functional studies of a pathogenicity island protein from Staphylococcus aureus
To be Published
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1TS2
 | | T128A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1997-10-09 | | Release date: | 1998-12-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
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1TS3
 | | H135A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1997-10-10 | | Release date: | 1998-12-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
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1EXF
 | | EXFOLIATIVE TOXIN A | | Descriptor: | EXFOLIATVE TOXIN A, GLYCINE | | Authors: | Vath, G.M, Earhart, C.A, Rago, J.V, Kim, M.H, Bohach, G.A, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-10-22 | | Release date: | 1998-02-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structure of the superantigen exfoliative toxin A suggests a novel regulation as a serine protease.
Biochemistry, 36, 1997
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1FNU
 | | STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | | Descriptor: | CADMIUM ION, EXOTOXIN TYPE A PRECURSOR (ALLELE 1) | | Authors: | Earhart, C.A, Vath, G.M, Roggiani, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 2000-08-23 | | Release date: | 2000-11-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structure of streptococcal pyrogenic exotoxin A reveals a novel metal cluster.
Protein Sci., 9, 2000
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1FNV
 | | STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | | Descriptor: | CADMIUM ION, EXOTOXIN TYPE A PRECURSOR (ALLELE 1) | | Authors: | Earhart, C.A, Vath, G.M, Roggiani, M, Schlievert, P.M, Ohlendorf, D.H. | | Deposit date: | 2000-08-23 | | Release date: | 2000-11-17 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of streptococcal pyrogenic exotoxin A reveals a novel metal cluster.
Protein Sci., 9, 2000
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1JWU
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-05 | | Release date: | 2003-07-08 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1JWS
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-05 | | Release date: | 2003-07-08 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1JWM
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-04 | | Release date: | 2003-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1KTK
 | | Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1) | | Descriptor: | Exotoxin type C, T-cell receptor beta chain | | Authors: | Sundberg, E.J, Li, H, Llera, A.S, McCormick, J.K, Tormo, J, Karjalainen, K, Schlievert, P.M, Mariuzza, R.A. | | Deposit date: | 2002-01-16 | | Release date: | 2002-06-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
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4TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: TETRAGONAL P4(1)2(1)2 CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1, ZINC ION | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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5TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: ORTHORHOMBIC P222(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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2TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-04 | | Release date: | 1997-12-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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3TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 TETRAMUTANT, P2(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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6PAJ
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2ICI
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1ESF
 | | STAPHYLOCOCCAL ENTEROTOXIN A | | Descriptor: | CADMIUM ION, STAPHYLOCOCCAL ENTEROTOXIN A | | Authors: | Schad, E.M, Svensson, L.A. | | Deposit date: | 1995-05-25 | | Release date: | 1996-07-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the superantigen staphylococcal enterotoxin type A.
EMBO J., 14, 1995
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1HQR
 | | CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II | | Descriptor: | HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ... | | Authors: | Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R. | | Deposit date: | 2000-12-19 | | Release date: | 2001-01-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
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3I46
 | | Crystal structure of beta toxin from Staphylococcus aureus F277A, P278A mutant with bound calcium ions | | Descriptor: | Beta-hemolysin, CALCIUM ION, CHLORIDE ION | | Authors: | Huseby, M, Shi, K, Kruse, A.C, Ohlendorf, D.H. | | Deposit date: | 2009-07-01 | | Release date: | 2010-07-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
To be Published
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3I41
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