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8GKG
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BU of 8gkg by Molmil
Human TRPV3 pentamer structure
Descriptor: Transient receptor potential cation channel subfamily V member 3
Authors:Lansky, S, Betancourt, J.M, Scheuring, S.
Deposit date:2023-03-18
Release date:2023-09-06
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (4.38 Å)
Cite:A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
8GKA
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BU of 8gka by Molmil
Human TRPV3 tetramer structure, closed conformation
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
Authors:Lansky, S, Betancourt, J.M, Scheuring, S.
Deposit date:2023-03-17
Release date:2023-09-06
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:A pentameric TRPV3 channel with a dilated pore.
Nature, 621, 2023
4CHW
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BU of 4chw by Molmil
The electron crystallography structure of the cAMP-free potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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BU of 4chv by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
6SB1
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BU of 6sb1 by Molmil
Crystal structure of murine perforin-2 P2 domain crystal form 1
Descriptor: CHLORIDE ION, GLYCEROL, Macrophage-expressed gene 1 protein
Authors:Ni, T, Ginger, L, Gilbert, R.J.C.
Deposit date:2019-07-18
Release date:2020-02-05
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB3
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BU of 6sb3 by Molmil
CryoEM structure of murine perforin-2 ectodomain in a pre-pore form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Ni, T, Yu, X, Gilbert, R.J.C.
Deposit date:2019-07-18
Release date:2020-02-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB4
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Crystal structure of murine perforin-2 P2 domain crystal form 2
Descriptor: Macrophage-expressed gene 1 protein
Authors:Ni, T, Yu, X, Ginger, L, Gilbert, R.J.C.
Deposit date:2019-07-18
Release date:2020-02-05
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
6SB5
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BU of 6sb5 by Molmil
CryoEM structure of murine perforin-2 ectodomain in a pore form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein
Authors:Ni, T, Yu, X, Gilbert, R.J.C.
Deposit date:2019-07-18
Release date:2020-02-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
7RXB
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BU of 7rxb by Molmil
afTMEM16 lipid scramblase in C18 lipid nanodiscs in the absence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
Authors:Feng, Z, Accardi, A.
Deposit date:2021-08-22
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXA
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BU of 7rxa by Molmil
afTMEM16 DE/AA mutant in C14 lipid nanodiscs in the presence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
Authors:Feng, Z, Accardi, A.
Deposit date:2021-08-22
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RX2
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BU of 7rx2 by Molmil
afTMEM16 in C22 lipid nanodiscs with MSP1E3 scaffold protein in the presnece of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-21
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXG
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BU of 7rxg by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, full dimer
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-23
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.28 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RWJ
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BU of 7rwj by Molmil
afTMEM16 in C22 lipid nanodiscs with MSP2N2 scaffold protein in the presnece of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, Plasma membrane channel protein (Aqy1), ...
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-20
Release date:2022-05-18
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RX3
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BU of 7rx3 by Molmil
afTMEM16 in C14 lipid nanodiscs with MSP1E3 scaffold protein in the absence of Ca2+
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-21
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022
7RXH
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BU of 7rxh by Molmil
afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, monomer with extra lipids
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase
Authors:Falzone, M.E, Accardi, A.
Deposit date:2021-08-23
Release date:2022-05-18
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:TMEM16 scramblases thin the membrane to enable lipid scrambling.
Nat Commun, 13, 2022

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