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2IY3
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STRUCTURE OF THE E. COLI SIGNAL REGOGNITION PARTICLE
Descriptor:Signal recognition particle protein,Signal recognition particle 54 kDa protein, 4.5S RNA, SIGNAL SEQUENCE
Authors:Schaffitzel, C., Oswald, M., Berger, I., Ishikawa, T., Abrahams, J.P., Koerten, H.K., Koning, R.I., Ban, N.
Deposit date:2006-07-12
Release date:2006-11-02
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Structure of the E. Coli Signal Recognition Particle Bound to a Translating Ribosome
Nature, 444, 2006
6FEC
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HUMAN CAP-DEPENDENT 48S PRE-INITIATION COMPLEX
Descriptor:Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit E, ...
Authors:Schaffitzel, C., Schaffitzel, C.
Deposit date:2017-12-31
Release date:2018-03-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structure of a human cap-dependent 48S translation pre-initiation complex.
Nucleic Acids Res., 46, 2018
5MG3
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EM FITTED MODEL OF BACTERIAL HOLO-TRANSLOCON
Descriptor:Protein translocase subunit SecY, Protein translocase subunit SecE, Protein-export membrane protein SecG, ...
Authors:Schaffitzel, C., Botte, M.
Deposit date:2016-11-20
Release date:2016-12-28
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (14 Å)
Cite:A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion.
Sci Rep, 6, 2016
6EMK
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CRYO-EM STRUCTURE OF SACCHAROMYCES CEREVISIAE TARGET OF RAPAMYCIN COMPLEX 2
Descriptor:Serine/threonine-protein kinase TOR2, Target of rapamycin complex subunit LST8, Target of rapamycin complex 2 subunit TSC11, ...
Authors:Karuppasamy, M., Kusmider, B., Oliveira, T.M., Gaubitz, C., Prouteau, M., Loewith, R., Schaffitzel, C.
Deposit date:2017-10-02
Release date:2017-12-06
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2.
Nat Commun, 8, 2017
6HCR
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SYNTHETIC SELF-ASSEMBLING ADDOMER PLATFORM FOR HIGHLY EFFICIENT VACCINATION BY GENETICALLY-ENCODED MULTI-EPITOPE DISPLAY
Descriptor:Penton protein
Authors:Bufton, J.C., Berger, I., Schaffitzel, C., Garzoni, F., Rabi, F.A.
Deposit date:2018-08-16
Release date:2019-08-28
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display.
Sci Adv, 5, 2019
2AKH
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NORMAL MODE-BASED FLEXIBLE FITTED COORDINATES OF A NON-TRANSLOCATING SECYEG PROTEIN-CONDUCTING CHANNEL INTO THE CRYO-EM MAP OF A SECYEG-NASCENT CHAIN-70S RIBOSOME COMPLEX FROM E. COLI
Descriptor:Protein-export membrane protein secG, Preprotein translocase secY subunit, Preprotein translocase secE subunit
Authors:Mitra, K.M., Schaffitzel, C., Shaikh, T., Tama, F., Jenni, S., Brooks III, C.L., Ban, N., Frank, J.
Deposit date:2005-08-03
Release date:2005-11-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (14.9 Å)
Cite:Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
2AKI
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NORMAL MODE-BASED FLEXIBLE FITTED COORDINATES OF A TRANSLOCATING SECYEG PROTEIN-CONDUCTING CHANNEL INTO THE CRYO-EM MAP OF A SECYEG-NASCENT CHAIN-70S RIBOSOME COMPLEX FROM E. COLI
Descriptor:Protein-export membrane protein secG, Preprotein translocase secY subunit, Preprotein translocase secE subunit
Authors:Mitra, K., Schaffitzel, C., Shaikh, T., Tama, F., Jenni, S., Brooks III, C.L., Ban, N., Frank, J.
Deposit date:2005-08-03
Release date:2005-11-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (14.9 Å)
Cite:Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
2VRH
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STRUCTURE OF THE E. COLI TRIGGER FACTOR BOUND TO A TRANSLATING RIBOSOME
Descriptor:TRIGGER FACTOR, 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, ...
Authors:Merz, F., Boehringer, D., Schaffitzel, C., Preissler, S., Hoffmann, A., Maier, T., Rutkowska, A., Lozza, J., Ban, N., Bukau, B., Deuerling, E.
Deposit date:2008-04-07
Release date:2008-06-17
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (19 Å)
Cite:Molecular Mechanism and Structure of Trigger Factor Bound to the Translating Ribosome.
Embo J., 27, 2008
2XKV
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ATOMIC MODEL OF THE SRP-FTSY EARLY CONFORMATION
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, 4.5S RNA, CELL DIVISION PROTEIN FTSY
Authors:Estrozi, L.F., Boehringer, D., Shan, S.-o., Ban, N., Schaffitzel, C.
Deposit date:2010-07-13
Release date:2010-12-15
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Cryo-Em Structure of the E. Coli Translating Ribosome in Complex with Srp and its Receptor.
Nat.Struct.Mol.Biol., 18, 2011
3ZN8
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STRUCTURAL BASIS OF SIGNAL SEQUENCE SURVEILLANCE AND SELECTION BY THE SRP-SR COMPLEX
Descriptor:SIGNAL RECOGNITION PARTICLE PROTEIN, SIGNAL RECOGNITION PARTICLE RECEPTOR FTSY, 4.5 S RNA, ...
Authors:von Loeffelholz, O., Knoops, K., Ariosa, A., Zhang, X., Karuppasamy, M., Huard, K., Schoehn, G., Berger, I., Shan, S.O., Schaffitzel, C.
Deposit date:2013-02-13
Release date:2013-03-06
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Structural Basis of Signal Sequence Surveillance and Selection by the Srp-Sr Complex
Nat.Struct.Mol.Biol., 20, 2013
4CEK
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CRYSTAL STRUCTURE OF THE SECOND MIF4G DOMAIN OF HUMAN NONSENSE MEDIATED DECAY FACTOR UPF2
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 2
Authors:Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C., Cusack, S.
Deposit date:2013-11-11
Release date:2013-12-11
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2.
Nucleic Acids Res., 42, 2014
4CEM
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CRYSTAL STRUCTURE OF THE FIRST MIF4G DOMAIN OF HUMAN NONSENSE MEDIATED DECAY FACTOR UPF2
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 2
Authors:Clerici, M., Deniaud, A., Boehm, V., Gehring, N.H., Schaffitzel, C., Cusack, S.
Deposit date:2013-11-11
Release date:2013-12-11
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2.
Nucleic Acids Res., 42, 2014
4V5B
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STRUCTURE OF PDF BINDING HELIX IN COMPLEX WITH THE RIBOSOME
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Bingel-Erlenmeyer, R., Kohler, R., Kramer, G., Sandikci, A., Antolic, S., Maier, T., Schaffitzel, C., Wiedmann, B., Bukau, B., Ban, N.
Deposit date:2007-11-22
Release date:2014-07-09
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing.
Nature, 452, 2008
5AKA
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EM STRUCTURE OF RIBOSOME-SRP-FTSY COMPLEX IN CLOSED STATE
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:von Loeffelholz, O., Jiang, Q., Ariosa, A., Karuppasamy, M., Huard, K., Berger, I., Shan, S., Schaffitzel, C.
Deposit date:2015-03-03
Release date:2015-03-25
Last modified:2017-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Ribosome-Srp-Ftsy Cotranslational Targeting Complex in the Closed State.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V4V
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STRUCTURE OF A PRE-TRANSLOCATIONAL E. COLI RIBOSOME OBTAINED BY FITTING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO CRYO-EM MAP EMD-1056
Descriptor:16S ribosomal RNA, tRNA, 30S ribosomal subunit protein S2, ...
Authors:Mitra, K., Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V4W
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STRUCTURE OF A SECM-STALLED E. COLI RIBOSOME COMPLEX OBTAINED BY FITTING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO CRYO-EM MAP EMD-1143
Descriptor:16S ribosomal RNA, tRNA, 30S ribosomal subunit protein S2, ...
Authors:Mitra, K., Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4WV4
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HETERODIMER OF TAF8/TAF10
Descriptor:Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 8, GLYCEROL, ...
Authors:Trowitzsch, S.
Deposit date:2014-11-04
Release date:2015-01-28
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
4WV6
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HETERODIMER OF IMPORTIN ALPHA 1 WITH NUCLEAR LOCALIZATION SIGNAL OF TAF8
Descriptor:Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8, 1,2-ETHANEDIOL
Authors:Trowitzsch, S.
Deposit date:2014-11-04
Release date:2015-01-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.
Nat Commun, 6, 2015
3BBU
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THE HSP15 PROTEIN FITTED INTO THE LOW RESOLUTION CRYO-EM MAP OF THE 50S.NC-TRNA.HSP15 COMPLEX
Descriptor:Heat Shock Protein 15
Authors:Jiang, L., Abrahams, J.P.
Deposit date:2007-11-11
Release date:2008-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15.
J.Mol.Biol., 386, 2009
3BBV
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THE TRNA(PHE) FITTED INTO THE LOW RESOLUTION CRYO-EM MAP OF THE 50S.NC-TRNA.HSP15 COMPLEX
Descriptor:tRNA(Phe)
Authors:Jiang, L., Abrahams, J.P.
Deposit date:2007-11-11
Release date:2008-10-21
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15.
J.Mol.Biol., 386, 2009
3BBX
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THE HSP15 PROTEIN FITTED INTO THE LOW RESOLUTION CRYO-EM MAP OF THE 50S.NC-TRNA.HSP15 COMPLEX
Descriptor:5S ribosomal RNA, 23S ribosomal RNA, 50S ribosomal protein L25, ...
Authors:Jiang, L., Abrahams, J.P.
Deposit date:2007-11-11
Release date:2008-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15.
J.Mol.Biol., 386, 2009