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6S9T
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BU of 6s9t by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3
Descriptor: Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL
Authors:Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
Deposit date:2019-07-15
Release date:2019-10-09
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S9S
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BU of 6s9s by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10
Descriptor: Darpin 10, LIM domain-binding protein 1
Authors:Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
Deposit date:2019-07-15
Release date:2019-10-09
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6FP7
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BU of 6fp7 by Molmil
mTFP1/DARPin 1238_E11 complex in space group P6522
Descriptor: DARPin1238_E11, GFP-like fluorescent chromoprotein cFP484, GLYCEROL
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FP8
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BU of 6fp8 by Molmil
mTFP1/DARPin 1238_E11 complex in space group C2
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DARPin1238_E11, ...
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FP9
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BU of 6fp9 by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_E11
Descriptor: 1,2-ETHANEDIOL, DARPin 1238_E11, SULFATE ION
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FPA
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BU of 6fpa by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group P212121
Descriptor: DARPin 1238_G01
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6FPB
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BU of 6fpb by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group I4
Descriptor: CHLORIDE ION, DARPin 1238_G01
Authors:Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
Deposit date:2018-02-09
Release date:2018-10-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.617 Å)
Cite:DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6S9R
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BU of 6s9r by Molmil
Crystal structure of SSDP from D. melanogaster
Descriptor: Sequence-specific single-stranded DNA-binding protein, isoform A
Authors:Renko, M, Bienz, M.
Deposit date:2019-07-15
Release date:2019-10-09
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
8P9E
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BU of 8p9e by Molmil
Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11
Descriptor: Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ...
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
8P9D
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BU of 8p9d by Molmil
Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2
Descriptor: Darpin 1810 A2, Tumor protein 63, Tumor protein p73
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
8P9C
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BU of 8p9c by Molmil
Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11
Descriptor: 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ...
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
7B4T
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BU of 7b4t by Molmil
Broadly neutralizing DARPin bnD.1 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.1, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), SULFATE ION
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2022-06-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4V
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BU of 7b4v by Molmil
Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.2, CHLORIDE ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), ...
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2022-06-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4W
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BU of 7b4w by Molmil
Broadly neutralizing DARPin bnD.3 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.3, ...
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2022-06-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7B4U
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BU of 7b4u by Molmil
Broadly neutralizing DARPin bnD.2 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Descriptor: Broadly neutralizing DARPin bnD.2, CALCIUM ION, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
Authors:Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
Deposit date:2020-12-02
Release date:2021-11-24
Last modified:2022-06-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7ZYU
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BU of 7zyu by Molmil
HDAC6 ZnF domain inhibitor - DARPin (Designed Ankyrin repeat protein) F10
Descriptor: 1,2-ETHANEDIOL, Designed Ankyrin repeat protein F10, Histone deacetylase 6, ...
Authors:Wang, L, Kempf, G.
Deposit date:2022-05-25
Release date:2022-06-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.
Cell Rep, 39, 2022
7PD4
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BU of 7pd4 by Molmil
structure of Adenylyl cyclase 9 in complex with MANT-GTP
Descriptor: Adenylate cyclase 9
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-04
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDG
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BU of 7pdg by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDH
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BU of 7pdh by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDE
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BU of 7pde by Molmil
Structure of Adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDD
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BU of 7pdd by Molmil
Focus refinement of soluble domain of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PD8
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BU of 7pd8 by Molmil
Structure of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-04
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDF
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BU of 7pdf by Molmil
focus refinement of soluble domain of adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-26
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7DNG
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BU of 7dng by Molmil
DARPin 63_B7 in complex with linear V3-crown (MN) peptide
Descriptor: DARPin 63_B7, linear V3-crown (MN) peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
7DNE
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BU of 7dne by Molmil
DARPin 5m3_D12 in complex with V3-IY (MN) crown mimetic
Descriptor: DARPin 5m3_D12, V3-IY (MN) crown mimetic peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021

 

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