4X9E
 
 | | DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules | | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, RNA (5'-R(P*CP*CP*C)-3') | | Authors: | Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M. | | Deposit date: | 2014-12-11 | | Release date: | 2015-02-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
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2AE9
 | | Solution Structure of the theta subunit of DNA polymerase III from E. coli | | Descriptor: | DNA polymerase III, theta subunit | | Authors: | Mueller, G.A, Kirby, T.W, Derose, E.F, Li, D, Schaaper, R.M, London, R.E. | | Deposit date: | 2005-07-21 | | Release date: | 2005-10-18 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Nuclear Magnetic Resonance Solution Structure of the Escherichia coli DNA Polymerase III {theta} Subunit.
J.Bacteriol., 187, 2005
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4XDS
 | | Deoxyguanosinetriphosphate Triphosphohydrolase from Escherichia coli with Nickel | | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, NICKEL (II) ION, SULFATE ION | | Authors: | Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M. | | Deposit date: | 2014-12-19 | | Release date: | 2015-02-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.354 Å) | | Cite: | Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
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2IDO
 | | Structure of the E. coli Pol III epsilon-Hot proofreading complex | | Descriptor: | 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ... | | Authors: | Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C. | | Deposit date: | 2006-09-15 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006
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1SE7
 | | Solution structure of the E. coli bacteriophage P1 encoded HOT protein: a homologue of the theta subunit of E. coli DNA polymerase III | | Descriptor: | HOMOLOGUE OF THE THETA SUBUNIT OF DNA POLYMERASE III | | Authors: | DeRose, E.F, Kirby, T.W, Mueller, G.A, Chikova, A.K, Schaaper, R.M, London, R.E. | | Deposit date: | 2004-02-16 | | Release date: | 2004-12-14 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Phage Like It HOT: Solution Structure of the Bacteriophage P1-Encoded HOT Protein, a Homolog of the theta Subunit of E. coli DNA Polymerase III
Structure, 12, 2004
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7TU5
 | | Structure of the L. blandensis dGTPase in the apo form | | Descriptor: | MAGNESIUM ION, dGTP triphosphohydrolase | | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU6
 | | Structure of the L. blandensis dGTPase bound to dATP | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU8
 | | Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU7
 | | Structure of the L. blandensis dGTPase H125A mutant bound to dGTP | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7U65
 | | Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 | | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase | | Authors: | Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-03-03 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7U67
 | | Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and GTP | | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, Inhibitor of dGTPase, ... | | Authors: | Klemm, B.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-03-03 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7U66
 | | Structure of E. coli dGTPase bound to T7 bacteriophage protein Gp1.2 and dGTP | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, Inhibitor of dGTPase, ... | | Authors: | Klemm, B.P, Dillard, L.B, Borgnia, M.J, Schaaper, R.M. | | Deposit date: | 2022-03-03 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7LWZ
 | | Apo Structure of Vibrio cholerae dGTPase protein VC1979 | | Descriptor: | Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1, NICKEL (II) ION | | Authors: | Sikkema, A.P, Horng, J, Klemm, B.P, Schaaper, R.M, Hall, T.M.T. | | Deposit date: | 2021-03-02 | | Release date: | 2021-03-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Structure of Vibrio cholerae dGTPase protein VC1979
To Be Published
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2MDP
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7TU3
 | | Structure of the L. blandensis dGTPase del55-58 mutant | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU2
 | | Structure of the L. blandensis dGTPase R37A mutant bound to Mn | | Descriptor: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU1
 | | Structure of the L. blandensis dGTPase R37A mutant | | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, dGTP triphosphohydrolase | | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU0
 | | Structure of the L. blandensis dGTPase bound to Mn | | Descriptor: | MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase | | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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7TU4
 | | Structure of the L. blandensis dGTPase del55-58 mutant bound to Mn | | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, SULFATE ION, ... | | Authors: | Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T. | | Deposit date: | 2022-02-02 | | Release date: | 2022-06-01 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
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