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2CC1
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CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE FROM MYCOBACTERIUM FORTUITUM
分子名称:Beta-lactamase
著者Sauvage, E., Fonze, E., Charlier, P.
登録日2006-01-11
公開日2006-01-13
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity.
Antimicrob. Agents Chemother., 50, 2006
2WK0
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CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE BS3 INHIBITED BY 6- BETA-IODOPENICILLANATE.
分子名称:BETA-LACTAMASE, (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, CHLORIDE ION, ...
著者Sauvage, E., Zervosen, A., Dive, G., Herman, R., Kerff, F., Amoroso, A., Fonze, E., Pratt, R.F., Luxen, A., Charlier, P.
登録日2009-06-03
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
4BJP
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CRYSTAL STRUCTURE OF E. COLI PENICILLIN BINDING PROTEIN 3
分子名称:PENICILLIN BINDING PROTEIN TRANSPEPTIDASE DOMAIN PROTEIN, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ...
著者Sauvage, E., Joris, M., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2013-04-19
公開日2014-05-07
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Penicillin-Binding Protein 3 (Pbp3) from Escherichia Coli.
Plos One, 9, 2014
4BJQ
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CRYSTAL STRUCTURE OF E. COLI PENICILLIN BINDING PROTEIN 3, DOMAIN V88- S165
分子名称:PENICILLIN BINDING PROTEIN TRANSPEPTIDASE DOMAIN PROTEIN, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Sauvage, E., Joris, M., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2013-04-19
公開日2014-05-07
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Penicillin-Binding Protein 3 (Pbp3) from Escherichia Coli.
Plos One, 9, 2014
2WKE
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CRYSTAL STRUCTURE OF THE ACTINOMADURA R39 DD-PEPTIDASE INHIBITED BY 6- BETA-IODOPENICILLANATE.
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, SULFATE ION, ...
著者Sauvage, E., Herman, R., Kerff, F., Charlier, P.
登録日2009-06-10
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
1W5D
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CRYSTAL STRUCTURE OF PBP4A FROM BACILLUS SUBTILIS
分子名称:PENICILLIN-BINDING PROTEIN, CALCIUM ION
著者Sauvage, E., Herman, R., Petrella, S., Duez, C., Frere, J.M., Charlier, P.
登録日2004-08-06
公開日2005-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Bacillus Subtilis Penicillin-Binding Protein 4A, and its Complex with a Peptidoglycan Mimetic Peptide.
J.Mol.Biol., 371, 2007
1W79
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CRYSTAL STRUCTURE OF THE DD-TRANSPEPTIDASE-CARBOXYPEPTIDASE FROM ACTINOMADURA R39
分子名称:D-alanyl-D-alanine carboxypeptidase, SULFATE ION, MAGNESIUM ION
著者Sauvage, E., Herman, R., Petrella, S., Duez, C., Frere, J.M., Charlier, P.
登録日2004-08-31
公開日2005-06-28
最終更新日2018-12-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
J. Biol. Chem., 280, 2005
1W8Q
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CRYSTAL STRUCTURE OF THE DD-TRANSPEPTIDASE-CARBOXYPEPTIDASE FROM ACTINOMADURA R39
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, COBALT (II) ION
著者Sauvage, E., Herman, R., Petrella, S., Duez, C., Frere, J.M., Charlier, P.
登録日2004-09-24
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure of the Actinomadura R39 Dd-Peptidase Reveals New Domains in Penicillin-Binding Proteins.
J.Biol.Chem., 280, 2005
1W8Y
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CRYSTAL STRUCTURE OF THE NITROCEFIN ACYL-DD-PEPTIDASE FROM ACTINOMADURA R39.
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, MAGNESIUM ION, ...
著者Sauvage, E., Herman, R., Petrella, S., Duez, C., Frere, J.M., Charlier, P.
登録日2004-10-01
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Actinomadura R39 Dd- Peptidase Reveals New Domains in Penicillin- Binding Proteins.
J.Biol.Chem., 280, 2005
2J9P
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CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS PBP4A, AND ITS COMPLEX WITH A PEPTIDOGLYCAN MIMETIC PEPTIDE.
分子名称:D-alanyl-D-alanine carboxypeptidase DacC, (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, D-ALANINE
著者Sauvage, E., Herman, R., Kerff, F., Duez, C., Charlier, P.
登録日2006-11-15
公開日2007-07-03
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide.
J. Mol. Biol., 371, 2007
2VGJ
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CRYSTAL STRUCTURE OF ACTINOMADURA R39 DD-PEPTIDASE COMPLEXED WITH A PEPTIDOGLYCAN-MIMETIC CEPHALOSPORIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, CEPHALOSPORIN, SULFATE ION, ...
著者Sauvage, E., kerff, F., Herman, R., Charlier, P.
登録日2007-11-14
公開日2008-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
2VGK
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CRYSTAL STRUCTURE OF ACTINOMADURA R39 DD-PEPTIDASE COMPLEXED WITH A PEPTIDOGLYCAN-MIMETIC CEPHALOSPORIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, SULFATE ION, ...
著者Sauvage, E., kerff, F., Herman, R., Charlier, P.
登録日2007-11-14
公開日2008-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structures of Complexes of Bacterial Dd-Peptidases with Peptidoglycan-Mimetic Ligands: The Substrate Specificity Puzzle.
J.Mol.Biol., 381, 2008
6G0K
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CRYSTAL STRUCTURE OF ENTEROCOCCUS FAECIUM D63R PENICILLIN-BINDING PROTEIN 5 (PBP5FM)
分子名称:Low affinity penicillin-binding protein 5 (PBP5), SULFATE ION
著者Sauvage, E., El Gachi, M., Herman, R., Kerff, F., Charlier, P.
登録日2018-03-19
公開日2019-04-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of inactivation of Enterococcus faecium penicillin binding protein 5 by ceftobiprole.
To Be Published
6G88
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CRYSTAL STRUCTURE OF ENTEROCOCCUS FAECIUM D63R PENICILLIN-BINDING PROTEIN 5 (PBP5FM)
分子名称:Low affinity penicillin-binding protein 5 (PBP5), (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyrrolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, SULFATE ION
著者Sauvage, E., El Gachi, M., Herman, R., Kerff, F., Charlier, P.
登録日2018-04-08
公開日2019-04-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of inactivation of Enterococcus faecium penicillin binding protein 5 by ceftobiprole.
To Be Published
2X71
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STRUCTURAL BASIS FOR THE INTERACTION OF LACTIVICINS WITH SERINE BETA- LACTAMASES
分子名称:BETA-LACTAMASE, (2E)-2-{[(2S)-2-(ACETYLAMINO)-2-CARBOXYETHOXY]IMINO}PENTANEDIOIC ACID, ETHANOL, ...
著者Sauvage, E., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2010-02-22
公開日2010-07-14
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Interaction of Lactivicins with Serine Beta-Lactamases.
J.Med.Chem., 53, 2010
2XK1
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD-PEPTIDASE AND A BORONATE INHIBITOR
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, [(1S)-1-{[(2-benzylphenyl)carbonyl]amino}ethyl](trihydroxy)borate(1-), SULFATE ION, ...
著者Sauvage, E., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2010-07-07
公開日2011-01-26
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
2XLN
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD-PEPTIDASE AND A BORONATE INHIBITOR
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE,, [(1S)-1-{[(2,6-DIMETHOXYPHENYL)CARBONYL]AMINO}ETHYL]BORONIC ACID, SULFATE ION, ...
著者Sauvage, E., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2010-07-21
公開日2011-01-26
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
2Y4A
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UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, {[(2-chlorobenzoyl)amino]methyl}boronic acid, SULFATE ION, ...
著者Sauvage, E., Zervosen, A., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2011-01-05
公開日2011-07-27
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
2Y55
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UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, PHENYLACETAMIDOMETHYL BORONIC ACID, SULFATE ION, ...
著者Sauvage, E., Zervosen, A., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2011-01-12
公開日2011-07-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
2Y59
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UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, TRIHYDROXY-[[(2-NITROPHENYL)CARBONYLAMINO]METHYL]BORON, SULFATE ION, ...
著者Sauvage, E., Zervosen, A., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2011-01-12
公開日2011-07-27
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
3B3X
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CRYSTAL STRUCTURE OF CLASS A BETA-LACTAMASE OF BACILLUS LICHENIFORMIS BS3 WITH AMINOCITRATE
分子名称:Beta-lactamase, 2-(carboxymethyl)-D-aspartic acid
著者Sauvage, E., Herman, R., Kerff, F., Charlier, P.
登録日2007-10-23
公開日2007-11-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis
Bioorg.Med.Chem.Lett., 18, 2008
3ZCZ
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD-PEPTIDASE AND A TRIFLUOROKETONE INHIBITOR
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (2R)-2-amino-7-oxo-7-{[(2R,3S)-4,4,4-trifluoro-3-hydroxybutan-2-yl]amino}heptanoic acid, SULFATE ION, ...
著者Sauvage, E., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2012-11-23
公開日2013-03-27
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibition of Dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 Dd-Peptidase.
Biochemistry, 52, 2013
3ZVT
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UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, SULFATE ION, ...
著者Sauvage, E., Zervosen, A., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2011-07-27
公開日2012-02-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
3ZVW
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UNEXPECTED TRICOVALENT BINDING MODE OF BORONIC ACIDS WITHIN THE ACTIVE SITE OF A PENICILLIN BINDING PROTEIN
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, MAGNESIUM ION, ...
著者Sauvage, E., Zervosen, A., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2011-07-28
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
4B4X
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CRYSTAL STRUCTURE OF A COMPLEX BETWEEN ACTINOMADURA R39 DD-PEPTIDASE AND A SULFONAMIDE BORONATE INHIBITOR
分子名称:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, trihydroxy{(1S)-1-[(methylsulfonyl)amino]ethyl}borate(1-), SULFATE ION, ...
著者Cannella, S.E., Sauvage, E., Herman, R., Kerff, F., Rocaboy, M., Charlier, P.
登録日2012-08-01
公開日2013-08-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structure of a Complex between Actinomadura R39 Dd-Peptidase and a Boronate Inhibitor
To be Published