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6UM6
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BU of 6um6 by Molmil
Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Acharya, P, Henderson, R.C, Saunder, K.O, Haynes, B.F.
Deposit date:2019-10-09
Release date:2019-12-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
6UM5
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BU of 6um5 by Molmil
Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Acharya, P, Henderson, R.C, Saunders, K.O, Haynes, B.F.
Deposit date:2019-10-09
Release date:2019-12-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
6P3B
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BU of 6p3b by Molmil
Crystal structure of the anti-HIV antibody DH501 unmutated common ancestor (UCA)
Descriptor: 1,2-ETHANEDIOL, DH501UCA Fab Heavy chain, DH501UCA Fab Light chain
Authors:Nicely, N.I, Saunders, K.O.
Deposit date:2019-05-23
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Cooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycans.
Plos Pathog., 15, 2019
6U6O
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BU of 6u6o by Molmil
Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846
Descriptor: DH846 Fab heavy chain, DH846 Fab light chain
Authors:Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G.
Deposit date:2019-08-30
Release date:2021-03-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
6U6M
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BU of 6u6m by Molmil
Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH840.1
Descriptor: DH840.1 Fab heavy chain, DH840.1 Fab light chain
Authors:Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G.
Deposit date:2019-08-30
Release date:2021-03-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.683 Å)
Cite:Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
5IIE
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BU of 5iie by Molmil
STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3
Descriptor: antibody DH501 FabH chain, antibody DH501 light chain
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-03-01
Release date:2017-03-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
6UM7
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BU of 6um7 by Molmil
Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH270.mu1 Fab Heavy Chain, DH270.mu1 Fab Light chain, ...
Authors:Acharya, P, Henderson, R.C, Saunders, K, Haynes, B.F.
Deposit date:2019-10-09
Release date:2019-12-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science, 366, 2019
5T4Z
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BU of 5t4z by Molmil
STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
Descriptor: CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
Authors:Nicely, N.I, Haynes, B.F.
Deposit date:2016-08-30
Release date:2017-03-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
8SXJ
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BU of 8sxj by Molmil
CH505 Disulfide Stapled SOSIP Bound to CH235.12 Fab
Descriptor: CH235.12 Heavy Chain, CH235.12 Light Chain, Envelope glycoprotein gp160, ...
Authors:Henderson, R.
Deposit date:2023-05-22
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Microsecond dynamics control the HIV-1 Envelope conformation.
Sci Adv, 10, 2024
8SXI
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BU of 8sxi by Molmil
CH505 Disulfide Stapled SOSIP Bound to b12 Fab
Descriptor: Envelope glycoprotein gp160, HIV-1 gp41, b12 Heavy Chain, ...
Authors:Henderson, R.
Deposit date:2023-05-22
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Microsecond dynamics control the HIV-1 Envelope conformation.
Sci Adv, 10, 2024
7SG4
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BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
4S1R
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BU of 4s1r by Molmil
Crystal structure of a VRC01-lineage antibody, 45-VRC01.H08.F-117225, in complex with clade A/E HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of VRC01 light chain, Fab of VRC01-lineage antibody,45-VRC01.H08.F-117225 heavy chain, ...
Authors:Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D.
Deposit date:2015-01-14
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.214 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell(Cambridge,Mass.), 161, 2015
4S1Q
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BU of 4s1q by Molmil
Crystal structure of a VRC01-lineage antibody, 45-VRC01.H03+06.D-001739, in complex with clade A/E HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab of VRC01 light chain, Fab of VRC01-lineage antibody,45-VRC01.H03+06.D-001739 heavy chain, ...
Authors:Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D.
Deposit date:2015-01-14
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell(Cambridge,Mass.), 161, 2015
4S1S
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BU of 4s1s by Molmil
Crystal structure of a VRC01-lineage antibody, 45-VRC01.H5.F-185917, in complex with clade A/E HIV-1 gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fab of VRC01 light chain, ...
Authors:Kwon, Y.D, Yang, Y, Zhang, B, Kwong, P.D.
Deposit date:2015-01-14
Release date:2015-04-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell(Cambridge,Mass.), 161, 2015
7BH8
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BU of 7bh8 by Molmil
3H4-Fab HLA-E-VL9 co-complex
Descriptor: 3H4 Fab heavy chain, 3H4 Fab light chain, Beta-2-microglobulin, ...
Authors:Walters, L.C, Rozbesky, D.
Deposit date:2021-01-10
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Commun Biol, 5, 2022
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:Manne, K, Nicely, N.I, Acharya, P.
Deposit date:2020-07-13
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
6MFP
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BU of 6mfp by Molmil
Crystal Structure of the RV305 C1-C2 specific ADCC potent antibody DH677.3 Fab in complex with HIV-1 clade A/E gp120 and M48U1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Tolbert, W.D, Young, B, Pazgier, M.
Deposit date:2018-09-11
Release date:2019-09-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
J.Virol., 94, 2020
6MFJ
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BU of 6mfj by Molmil
Crystal structure of the ADCC potent antibody DH677.3 Fab elicited in the RV305 vaccine trial.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH677.3 Fab heavy chain, DH677.3 Fab light chain
Authors:Young, B, Tolbert, W.D, Pazgier, M.
Deposit date:2018-09-11
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.
J.Virol., 94, 2020
6MNR
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BU of 6mnr by Molmil
Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide
Descriptor: 1,2-ETHANEDIOL, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ...
Authors:Nicely, N.I.
Deposit date:2018-10-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
6MNQ
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BU of 6mnq by Molmil
Rhesus macaque anti-HIV V3 antibody DH727.2 with gp120 V3 ZAM18 peptide
Descriptor: 1,2-ETHANEDIOL, Ab DH727.2 heavy chain Fab fragment, Ab DH727.2 light chain, ...
Authors:Nicely, N.I.
Deposit date:2018-10-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
6MNS
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BU of 6mns by Molmil
Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide
Descriptor: Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, Envelope glylcoprotein, ...
Authors:Nicely, N.I.
Deposit date:2018-10-02
Release date:2019-07-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations.
Nat Commun, 10, 2019
4XMP
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BU of 4xmp by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, ...
Authors:Zhou, T, Srivatsan, S, Kwong, P.D.
Deposit date:2015-01-15
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7831 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
4XVS
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BU of 4xvs by Molmil
Crystal structure of HIV-1 donor 45 d45-01dG5 coreE gp120 with antibody 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 (VRC07_1995)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 45-VRC01.H01+07.O-863513/45-VRC01.L01+07.O-110653 Light chain, Donor 45 01dG5 coreE gp120, ...
Authors:Joyce, M.G, Mascola, J.R, Kwong, P.D.
Deposit date:2015-01-27
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
4XNZ
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BU of 4xnz by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ...
Authors:Zhou, T, Srivatsan, S, Kwong, P.D.
Deposit date:2015-01-16
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.389 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
4XNY
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BU of 4xny by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, ...
Authors:Zhou, T, Srivatsan, S, Kwong, P.D.
Deposit date:2015-01-16
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015

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