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5BW7
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CRYSTAL STRUCTURE OF NONFUCOSYLATED FC Y296W MUTANT COMPLEXED WITH BIS-GLYCOSYLATED SOLUBLE FORM OF FC GAMMA RECEPTOR IIIA
Descriptor:Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Isoda, Y., Yagi, H., Satoh, T., Shibata-Koyama, M., Masuda, K., Satoh, M., Kato, K., Iida, S.
Deposit date:2015-06-06
Release date:2015-10-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with Fc gamma RIIIa and Other Fc gamma Receptors
Plos One, 10, 2015
3AVE
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CRYSTAL STRUCTURE OF THE FUCOSYLATED FC FRAGMENT FROM HUMAN IMMUNOGLOBULIN G1
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Matsumiya, S., Yamaguchi, Y., Saito, J., Nagano, M., Sasakawa, H., Otaki, S., Satoh, M., Shitara, K., Kato, K.
Deposit date:2011-03-04
Release date:2011-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Corrigendum to "Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1" [J. Mol. Biol. 386/3 (2007) 767-779]
J.Mol.Biol., 408, 2011
1VD4
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SOLUTION STRUCTURE OF THE ZINC FINGER DOMAIN OF TFIIE ALPHA
Descriptor:Transcription initiation factor IIE, alpha subunit, ZINC ION
Authors:Okuda, M., Tanaka, A., Arai, Y., Satoh, M., Okamura, H., Nagadoi, A., Hanaoka, F., Ohkuma, Y., Nishimura, Y.
Deposit date:2004-03-18
Release date:2004-10-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.
J.Biol.Chem., 279, 2004
2DTS
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CRYSTAL STRUCTURE OF THE DEFUCOSYLATED FC FRAGMENT FROM HUMAN IMMUNOGLOBULIN G1
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Matsumiya, S., Yamaguchi, Y., Saito, J., Nagano, M., Sasakawa, H., Otaki, S., Satoh, M., Shitara, K., Kato, K.
Deposit date:2006-07-14
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural comparison of fucosylated and nonfucosylated fc fragments of human immunoglobulin g1
J.Mol.Biol., 368, 2007
3AY4
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CRYSTAL STRUCTURE OF NONFUCOSYLATED FC COMPLEXED WITH BIS-GLYCOSYLATED SOLUBLE FORM OF FC GAMMA RECEPTOR IIIA
Descriptor:Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor III-A, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mizushima, T., Takemoto, E., Yagi, H., Shibata-Koyama, M., Isoda, Y., Iida, S., Satoh, M., Kato, K.
Deposit date:2011-04-28
Release date:2011-08-03
Last modified:2011-11-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans
Genes Cells, 16, 2011
3VNG
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CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH SYNTHETIC SMALL MOLECULAR BASED ON A CO-CRYSTALLIZATION
Descriptor:Kelch-like ECH-associated protein 1, 2-(3-((3-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)ureido)methyl)phenoxy)acetic acid
Authors:Kunishima, N., Tanaka, T., Satoh, M., Saburi, H.
Deposit date:2012-01-12
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization
To be Published
3VNH
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CRYSTAL STRUCTURE OF KEAP1 SOAKED WITH SYNTHETIC SMALL MOLECULAR
Descriptor:Kelch-like ECH-associated protein 1, 2-(3-((3-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)ureido)methyl)phenoxy)acetic acid
Authors:Kunishima, N., Tanaka, T., Satoh, M., Saburi, H.
Deposit date:2012-01-12
Release date:2013-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Keap1 Soaked with Synthetic Small Molecular
To be Published
2RNQ
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SOLUTION STRUCTURE OF THE C-TERMINAL ACIDIC DOMAIN OF TFIIE ALPHA
Descriptor:Transcription initiation factor IIE subunit alpha
Authors:Okuda, M., Nishimura, Y.
Deposit date:2008-01-31
Release date:2008-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
Embo J., 27, 2008
2RNR
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SOLUTION STRUCTURE OF THE COMPLEX BETWEEN TFIIE ALPHA C-TERMINAL ACIDIC DOMAIN AND TFIIH P62 PH DOMAIN
Descriptor:Transcription initiation factor IIE subunit alpha, TFIIH basal transcription factor complex p62 subunit
Authors:Okuda, M., Nishimura, Y.
Deposit date:2008-01-31
Release date:2008-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
Embo J., 27, 2008
3AN3
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MO3S
Descriptor:Peroxisome proliferator-activated receptor gamma, (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid
Authors:Oyama, T., Ohashi, M., Waku, T., Miyachi, H., Morikawa, K.
Deposit date:2010-08-30
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
3AN4
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MO4R
Descriptor:Peroxisome proliferator-activated receptor gamma, (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid
Authors:Oyama, T., Ohashi, M., Waku, T., Miyachi, H., Morikawa, K.
Deposit date:2010-08-30
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011