Author results

199D
  • Download 199d
  • View 199d
Molmil generated image of 199d
SOLUTION STRUCTURE OF THE MONOALKYLATED MITOMYCIN C-DNA COMPLEX
Descriptor:DNA (5'-D(*(DI)P*CP*AP*CP*GP*TP*CP*(DI)P*T)-3'), DNA (5'-D(*AP*CP*GP*AP*CP*GP*TP*GP*C)-3'), CARBAMIC ACID 2,6-DIAMINO-5-METHYL-4,7-DIOXO-2,3,4,7-TETRAHYDRO-1H-3A-AZA-CYCLOPENTA[A]INDEN-8-YLMETHYL ESTER
Authors:Sastry, M., Fiala, R., Lipman, R., Tomasz, M., Patel, D.J.
Deposit date:1994-12-01
Release date:1995-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the monoalkylated mitomycin C-DNA complex.
J.Mol.Biol., 247, 1995
1A03
  • Download 1a03
  • View 1a03
Molmil generated image of 1a03
THE THREE-DIMENSIONAL STRUCTURE OF CA2+-BOUND CALCYCLIN: IMPLICATIONS FOR CA2+-SIGNAL TRANSDUCTION BY S100 PROTEINS, NMR, 20 STRUCTURES
Descriptor:CALCYCLIN (RABBIT, CA2+)
Authors:Sastry, M., Ketchem, R.R., Crescenzi, O., Weber, C., Lubienski, M.J., Hidaka, H., Chazin, W.J.
Deposit date:1997-12-08
Release date:1999-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins.
Structure, 6, 1998
146D
  • Download 146d
  • View 146d
Molmil generated image of 146d
SOLUTION STRUCTURE OF THE MITHRAMYCIN DIMER-DNA COMPLEX
Descriptor:DNA (5'-D(*TP*CP*GP*CP*GP*A)-3'), 2,6-DIDEOXY-BETA-D-GLUCOSE, 2,6-DIDEOXY-BETA-D-GALACTOSE, ...
Authors:Sastry, M., Patel, D.J.
Deposit date:1993-11-09
Release date:1995-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the mithramycin dimer-DNA complex.
Biochemistry, 32, 1993
207D
  • Download 207d
  • View 207d
Molmil generated image of 207d
SOLUTION STRUCTURE OF MITHRAMYCIN DIMERS BOUND TO PARTIALLY OVERLAPPING SITES ON DNA
Descriptor:DNA (5'-D(*TP*AP*GP*CP*TP*AP*GP*CP*TP*A)-3'), 2,6-DIDEOXY-BETA-D-GLUCOSE, 2,6-DIDEOXY-BETA-D-GALACTOSE, ...
Authors:Sastry, M., Fiala, R., Patel, D.J.
Deposit date:1995-04-20
Release date:1995-09-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of mithramycin dimers bound to partially overlapping sites on DNA.
J.Mol.Biol., 251, 1995
1JWD
  • Download 1jwd
  • View 1jwd
Molmil generated image of 1jwd
CA2+-INDUCED STRUCTURAL CHANGES IN CALCYCLIN: HIGH-RESOLUTION SOLUTION STRUCTURE OF CA2+-BOUND CALCYCLIN.
Descriptor:Calcyclin
Authors:Maler, L., Sastry, M., Chazin, W.J.
Deposit date:2001-09-04
Release date:2002-03-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A structural basis for S100 protein specificity derived from comparative analysis of apo and Ca(2+)-calcyclin
J.Mol.Biol., 317, 2002
4MMQ
  • Download 4mmq
  • View 4mmq
Molmil generated image of 4mmq
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMR
  • Download 4mmr
  • View 4mmr
Molmil generated image of 4mmr
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Stewart-Jones, G.B.E., McLellan, J.S., Joyce, M.G., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMS
  • Download 4mms
  • View 4mms
Molmil generated image of 4mms
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 5.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMT
  • Download 4mmt
  • View 4mmt
Molmil generated image of 4mmt
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS-CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Joyce, M.G., Mclellan, J.S., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMU
  • Download 4mmu
  • View 4mmu
Molmil generated image of 4mmu
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS-CAV1 AT PH 5.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION, ...
Authors:Joyce, M.G., Mclellan, J.S., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMV
  • Download 4mmv
  • View 4mmv
Molmil generated image of 4mmv
CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS-CAV1-TRIC AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Stewart-Jones, G.B.E., McLellan, J.S., Joyce, M.G., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
5JDV
  • Download 5jdv
  • View 5jdv
Molmil generated image of 5jdv
HUMAN CARBONIC ANHYDRASE II (F131W) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-17
Release date:2017-01-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JE7
  • Download 5je7
  • View 5je7
Molmil generated image of 5je7
HUMAN CARBONIC ANHYDRASE II (F131Y) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-17
Release date:2017-01-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JEG
  • Download 5jeg
  • View 5jeg
Molmil generated image of 5jeg
HUMAN CARBONIC ANHYDRASE II (V121I) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-18
Release date:2017-01-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JEH
  • Download 5jeh
  • View 5jeh
Molmil generated image of 5jeh
HUMAN CARBONIC ANHYDRASE II (L198A) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-18
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JEP
  • Download 5jep
  • View 5jep
Molmil generated image of 5jep
HUMAN CARBONIC ANHYDRASE II (T199S) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-18
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JES
  • Download 5jes
  • View 5jes
Molmil generated image of 5jes
HUMAN CARBONIC ANHYDRASE II (V121T) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-benzothiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-18
Release date:2017-01-11
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.205 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JG3
  • Download 5jg3
  • View 5jg3
Molmil generated image of 5jg3
HUMAN CARBONIC ANHYDRASE II (121T/N67Q) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, 1,3-benzothiazole-2-sulfonamide, ZINC ION
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-19
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JG5
  • Download 5jg5
  • View 5jg5
Molmil generated image of 5jg5
HUMAN CARBONIC ANHYDRASE II (V121T/F131Y) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, 1,3-benzothiazole-2-sulfonamide, ZINC ION
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-19
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JGS
  • Download 5jgs
  • View 5jgs
Molmil generated image of 5jgs
HUMAN CARBONIC ANHYDRASE II (F131Y/L198A) COMPLEXED WITH BENZO[D]THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, 1,3-benzothiazole-2-sulfonamide, ZINC ION
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-20
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
5JGT
  • Download 5jgt
  • View 5jgt
Molmil generated image of 5jgt
HUMAN CARBONIC ANHYDRASE II (F131Y/L198A) COMPLEXED WITH 1,3-THIAZOLE-2-SULFONAMIDE
Descriptor:Carbonic anhydrase 2, ZINC ION, 1,3-thiazole-2-sulfonamide
Authors:Fox, J.M., Kang, K., Sastry, M., Sherman, W., Sankaran, B., Zwart, P.H., Whitesides, G.M.
Deposit date:2016-04-20
Release date:2017-01-11
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.
Angew. Chem. Int. Ed. Engl., 56, 2017
3TCL
  • Download 3tcl
  • View 3tcl
Molmil generated image of 3tcl
CRYSTAL STRUCTURE OF HIV-1 NEUTRALIZING ANTIBODY CH04
Descriptor:CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
Authors:Louder, R.K., McLellan, J.S., Pancera, M., Yang, Y., Zhang, B., Bonsignori, M., Kwong, P.D.
Deposit date:2011-08-09
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U2S
  • Download 3u2s
  • View 3u2s
Molmil generated image of 3u2s
CRYSTAL STRUCTURE OF PG9 FAB IN COMPLEX WITH V1V2 REGION FROM HIV-1 STRAIN ZM109
Descriptor:PG9 heavy chain, PG9 light chain, Envelope glycoprotein gp120, ...
Authors:McLellan, J.S., Pancera, M., Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U46
  • Download 3u46
  • View 3u46
Molmil generated image of 3u46
CH04H/CH02L P212121
Descriptor:CH04 Heavy chain Fab, CH02 Light chain Fab
Authors:Louder, R., Pancera, M., McLellan, J.S., Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4B
  • Download 3u4b
  • View 3u4b
Molmil generated image of 3u4b
CH04H/CH02L FAB P4
Descriptor:CH04 Heavy chain, CH02 Light chain
Authors:Pancera, M., Louder, R., Mclellan, J.S., KWong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
<12>