Author results

2D7E
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PRIA FROM E.COLI
Descriptor:Primosomal protein N'
Authors:Sasaki, K., Ose, T., Maenaka, K., Masai, H., Kohda, D.
Deposit date:2005-11-18
Release date:2006-11-07
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
2D7G
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CRYSTAL STRUCTURE OF THE AA COMPLEX OF THE N-TERMINAL DOMAIN OF PRIA
Descriptor:Primosomal protein N', DNA (5'-D(P*AP*A)-3')
Authors:Sasaki, K., Ose, T., Maenaka, K., Masai, H., Kohda, D.
Deposit date:2005-11-21
Release date:2006-11-07
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
2D7H
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CRYSTAL STRUCTURE OF THE CCC COMPLEX OF THE N-TERMINAL DOMAIN OF PRIA
Descriptor:Primosomal protein N', DNA (5'-D(P*CP*CP*C)-3')
Authors:Sasaki, K., Ose, T., Maenaka, K., Masai, H., Kohda, D.
Deposit date:2005-11-21
Release date:2006-11-07
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
2DWL
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CRYSTAL STRUCTURE OF THE PRIA PROTEIN COMPLEXED WITH OLIGONUCLEOTIDES
Descriptor:5'-D(*AP*(DC))-3', Primosomal protein N
Authors:Sasaki, K., Ose, T., Tanaka, T., Masai, H., Maenaka, K., Kohda, D.
Deposit date:2006-08-15
Release date:2006-11-07
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
2DWM
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CRYSTAL STRUCTURE OF THE PRIA PROTEIN COMPLEXED WITH OLIGONUCLEOTIDES
Descriptor:5'-D(*AP*T)-3', Primosomal protein N
Authors:Sasaki, K., Ose, T., Tanaka, T., Masai, H., Maenaka, K., Kohda, D.
Deposit date:2006-08-15
Release date:2006-11-07
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
2DWN
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CRYSTAL STRUCTURE OF THE PRIA PROTEIN COMPLEXED WITH OLIGONUCLEOTIDES
Descriptor:Primosomal protein N', DNA (5'-D(*A*G)-3')
Authors:Sasaki, K., Ose, T., Tanaka, T., Masai, H., Maenaka, K., Kohda, D.
Deposit date:2006-08-15
Release date:2006-11-07
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA.
EMBO J., 26, 2007
3W3D
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CRYSTAL STRUCTURE OF SMOOTH MUSCLE G ACTIN DNASE I COMPLEX
Descriptor:Actin, gamma-enteric smooth muscle, Deoxyribonuclease-1, ...
Authors:Sakabe, N., Sakabe, K., Sasaki, K., Kondo, H., Shimomur, M.
Deposit date:2012-12-20
Release date:2013-01-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined structure and solvent network of chicken gizzard G-actin DNase 1 complex at 1.8A resolution
Acta Crystallogr.,Sect.A, 49, 1993
1GCN
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X-RAY ANALYSIS OF GLUCAGON AND ITS RELATIONSHIP TO RECEPTOR BINDING
Descriptor:GLUCAGON
Authors:Blundell, T.L., Sasaki, K., Dockerill, S., Tickle, I.J.
Deposit date:1977-10-17
Release date:1977-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray analysis of glucagon and its relationship to receptor binding.
Nature, 257, 1975
3W7Y
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0.92A STRUCTURE OF 2ZN HUMAN INSULIN AT 100K
Descriptor:Insulin, ZINC ION
Authors:Sakabe, N., Sakabe, K., Sasaki, K., Murayoshi, M.
Deposit date:2013-03-11
Release date:2013-07-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:0.92A structure of 2Zn human insulin at 100K
To be Published
3W7Z
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1.15A STRUCTURE OF HUMAN 2ZN INSULIN AT 293K
Descriptor:Insulin, ZINC ION
Authors:Hoshikawa, N., Sasaki, K., Sakabe, N., Sakabe, K.
Deposit date:2013-03-11
Release date:2013-07-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:1.15A structure of human 2Zn insulin at 293K
To be Published
3W80
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CRYSTAL STRUCTURE OF DODECAMER HUMAN INSULIN WITH DOUBLE C-AXIS LENGTH OF THE HEXAMER 2 ZN INSULIN CELL
Descriptor:Insulin, ZINC ION
Authors:Murayoshi, M., Sasaki, K., Sakabe, N., Sakabe, K.
Deposit date:2013-03-11
Release date:2013-07-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of dodecamer insulin with double C-axis length of the hexamer 2 Zn insulin celll
To be Published
3A8U
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CRYSTAL STRUCTURE OF OMEGA-AMINO ACID:PYRUVATE AMINOTRANSFERASE
Descriptor:Omega-amino acid--pyruvate aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Watanabe, N., Sakabe, N., Sakabe, K., Sasaki, K.
Deposit date:2009-10-11
Release date:2009-11-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of omega-Amino Acid:Pyruvate Aminotransferase
to be published
2ZB5
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CRYSTAL STRUCTURE OF THE MEASLES VIRUS HEMAGGLUTININ (COMPLEX-SUGAR-TYPE)
Descriptor:Hemagglutinin protein, N-ACETYL-D-GLUCOSAMINE
Authors:Hashiguchi, T., Kajikawa, M., Maita, N., Takeda, M., Kuroki, K., Sasaki, K., Kohda, D., Yanagi, Y., Maenaka, K.
Deposit date:2007-10-16
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of measles virus hemagglutinin provides insight into effective vaccines
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ZB6
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CRYSTAL STRUCTURE OF THE MEASLES VIRUS HEMAGGLUTININ (OLIGO-SUGAR TYPE)
Descriptor:Hemagglutinin protein, N-ACETYL-D-GLUCOSAMINE
Authors:Hashiguchi, T., Kajikawa, M., Maita, N., Takeda, M., Kuroki, K., Sasaki, K., Kohda, D., Yanagi, Y., Maenaka, K.
Deposit date:2007-10-16
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of measles virus hemagglutinin provides insight into effective vaccines
Proc.Natl.Acad.Sci.Usa, 104, 2007
3W3E
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STRUCTURE OF VIGNA UNGUICULATA CHITINASE WITH REGULATION ACTIVITY OF THE PLANT CELL WALL
Descriptor:Cotyledoneous yieldin-like protein
Authors:Morohashi, K., Sasaki, K., Sakabe, N., Sakabe, K.
Deposit date:2012-12-20
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structure analysis of Vigna unguiculata chitinase with regulation activity of the yield threshold of cell wall
To be Published
5AXU
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CRYSTAL STRUCTURE OF CYPOVIRUS POLYHEDRA R13A MUTANT
Descriptor:Polyhedrin, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Abe, S., Ijiri, H., Negishi, H., Yamanaka, H., Sasaki, K., Hirata, K., Mori, H., Ueno, T.
Deposit date:2015-08-01
Release date:2015-11-11
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design of Enzyme-Encapsulated Protein Containers by In Vivo Crystal Engineering
Adv. Mater. Weinheim, 27, 2015
5AXV
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CRYSTAL STRUCTURE OF CYPOVIRUS POLYHEDRA R13K MUTANT
Descriptor:Polyhedrin, CYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Abe, S., Ijiri, H., Negishi, H., Yamanaka, H., Sasaki, K., Hirata, K., Mori, H., Ueno, T.
Deposit date:2015-08-01
Release date:2015-11-11
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Design of Enzyme-Encapsulated Protein Containers by In Vivo Crystal Engineering
Adv. Mater. Weinheim, 27, 2015
1UGL
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SOLUTION STRUCTURE OF S8-SP11
Descriptor:S-locus pollen protein
Authors:Mishima, M., Takayama, S., Sasaki, K., Jee, J.G., Kojima, C., Isogai, A., Shirakawa, M., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-16
Release date:2003-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Male Determinant Factor for Brassica Self-incompatibility
J.Biol.Chem., 278, 2003
3A0I
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HUMAN GLUCOKINASE IN COMPLEX WITH A SYNTHETIC ACTIVATOR
Descriptor:Glucokinase, ALPHA-D-GLUCOSE, 3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide, ...
Authors:Kamata, K., Mitsuya, M.
Deposit date:2009-03-19
Release date:2009-04-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators
Bioorg.Med.Chem.Lett., 19, 2009
3GOI
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HUMAN GLUCOKINASE IN COMPLEX WITH A SYNTHETIC ACTIVATOR
Descriptor:Glucokinase, ALPHA-D-GLUCOSE, 2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide
Authors:Kamata, K., Mitsuya, M.
Deposit date:2009-03-19
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators
Bioorg.Med.Chem.Lett., 19, 2009
3H1V
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HUMAN GLUCOKINASE IN COMPLEX WITH A SYNTHETIC ACTIVATOR
Descriptor:Glucokinase, ALPHA-D-GLUCOSE, 1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dione, ...
Authors:Kamata, K., Takahashi, K.
Deposit date:2009-04-14
Release date:2009-10-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators.
Bioorg.Med.Chem., 17, 2009
3FR0
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HUMAN GLUCOKINASE IN COMPLEX WITH 2-AMINO BENZAMIDE ACTIVATOR
Descriptor:Glucokinase, ALPHA-D-GLUCOSE, 2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide, ...
Authors:Kamata, K.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators
Bioorg.Med.Chem.Lett., 19, 2009
3WXA
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X-RAY CRYSTAL STRUCTURAL ANALYSIS OF THE COMPLEX BETWEEN ALG-2 AND SEC31A PEPTIDE
Descriptor:Programmed cell death protein 6, Protein transport protein Sec31A, ZINC ION
Authors:Takahashi, T., Suzuki, H., Kawasaki, M., Shibata, H., Wakatsuki, S., Maki, M.
Deposit date:2014-07-29
Release date:2015-03-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Analysis of the Complex between Penta-EF-Hand ALG-2 Protein and Sec31A Peptide Reveals a Novel Target Recognition Mechanism of ALG-2
Int J Mol Sci, 16, 2015
3AQA
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CRYSTAL STRUCTURE OF THE HUMAN BRD2 BD1 BROMODOMAIN IN COMPLEX WITH A BRD2-INTERACTIVE COMPOUND, BIC1
Descriptor:Bromodomain-containing protein 2, 1-[2-(1H-benzimidazol-2-ylsulfanyl)ethyl]-3-methyl-1,3-dihydro-2H-benzimidazole-2-thione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Umehara, T., Nakamura, Y., Terada, T., Shirouzu, M., Padmanabhan, B., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-10-27
Release date:2011-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Real-Time Imaging of Histone H4K12-Specific Acetylation Determines the Modes of Action of Histone Deacetylase and Bromodomain Inhibitors
Chem.Biol., 18, 2011
5K7K
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DESIGN AND OPTIMIZATION OF BIARYL ETHER ARYL SULFONAMIDES AS SELECTIVE INHIBITORS OF NAV1.7: DISCOVERY OF CLINICAL CANDIDATE PF-05089771
Descriptor:Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE, 4-[4-chloranyl-2-(1~{H}-pyrazol-4-yl)phenoxy]-3-cyano-~{N}-(1,3-thiazol-2-yl)benzenesulfonamide
Authors:Swain, N., Chrencik, J.
Deposit date:2016-05-26
Release date:2017-06-07
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.
J. Med. Chem., 60, 2017