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8AYE
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BU of 8aye by Molmil
E. coli 70S ribosome bound to thermorubin and fMet-tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Sanyal, S, Parajuli, N.P, Emmerich, A.G.
Deposit date:2022-09-02
Release date:2023-03-01
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.
Nat Commun, 14, 2023
2XEX
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BU of 2xex by Molmil
crystal structure of Staphylococcus aureus elongation factor G
Descriptor: CHLORIDE ION, ELONGATION FACTOR G, POTASSIUM ION
Authors:Chen, Y, Koripella, R.K, Sanyal, S, Selmer, M.
Deposit date:2010-05-19
Release date:2010-07-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Staphylococcus Aureus Elongation Factor G - Structure and Analysis of a Target for Fusidic Acid.
FEBS J., 277, 2010
5ADY
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BU of 5ady by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with HflX
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
Authors:Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
8BRM
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BU of 8brm by Molmil
Giardia ribosome in POST-T state, no E-site tRNA (A6)
Descriptor: 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-23
Release date:2023-03-15
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
8BSI
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BU of 8bsi by Molmil
Giardia ribosome chimeric hybrid-like GDP+Pi bound state (B1)
Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-25
Release date:2023-03-15
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
8BSJ
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BU of 8bsj by Molmil
Giardia Ribosome in PRE-T Classical State (C)
Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-25
Release date:2023-03-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (6.49 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
8BR8
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BU of 8br8 by Molmil
Giardia ribosome in POST-T state (A1)
Descriptor: 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-22
Release date:2023-03-15
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
8BTR
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BU of 8btr by Molmil
Giardia Ribosome in PRE-T Hybrid State (D2)
Descriptor: 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-29
Release date:2023-03-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
8BTD
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BU of 8btd by Molmil
Giardia Ribosome in PRE-T Hybrid State (D1)
Descriptor: 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ...
Authors:Majumdar, S, Emmerich, A.G, Sanyal, S.
Deposit date:2022-11-28
Release date:2023-03-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
7BBN
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BU of 7bbn by Molmil
Crystal structure of an ancient sequence-reconstructed Elongation Factor Tu (node 317)
Descriptor: Elongation Factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Majumdar, S, Bergfors, T, Sanyal, S.
Deposit date:2020-12-18
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 317)
To be published
6GFU
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BU of 6gfu by Molmil
Crystal structure of an ancient sequence-reconstructed Elongation Factor Tu (node 262)
Descriptor: Elongation Factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Majumdar, S, Tarafder, A.D, Ge, X, Kacar, B, Sanyal, S.
Deposit date:2018-05-02
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of an ancient sequence-reconstructed Elongation Factor Tu (node 262)
To Be Published
6HTW
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BU of 6htw by Molmil
Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 184)
Descriptor: Elongation Factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Majumdar, S, Bergfors, T, Sanyal, S.
Deposit date:2018-10-04
Release date:2019-10-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 184)
To be published
6I8R
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BU of 6i8r by Molmil
Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 170)
Descriptor: Elongation Factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Majumdar, S, Bergfors, T, Sanyal, S.
Deposit date:2018-11-20
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of an ancient sequence-reconstructed Elongation factor Tu (node 170)
To be published
7BV8
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BU of 7bv8 by Molmil
Mature 50S ribosomal subunit from RrmJ knock out E.coli strain
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Wang, W, Li, W.Q, Ge, X.L, Yan, K.G, Mandava, C.S, Sanyal, S, Gao, N.
Deposit date:2020-04-09
Release date:2020-07-01
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation.
Proc.Natl.Acad.Sci.USA, 117, 2020
3J9Z
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BU of 3j9z by Molmil
Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
Deposit date:2015-03-27
Release date:2015-07-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
3JA1
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BU of 3ja1 by Molmil
Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
2O0F
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BU of 2o0f by Molmil
Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3
Descriptor: Peptide chain release factor 3
Authors:Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H.
Deposit date:2006-11-27
Release date:2007-07-24
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (15.5 Å)
Cite:RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
4ADN
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BU of 4adn by Molmil
Fusidic acid resistance protein FusB
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FAR1, ...
Authors:Guo, X, Peisker, K, Backbro, K, Chen, Y, Kiran, R.K, Sanyal, S, Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2012-07-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
4ADO
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BU of 4ado by Molmil
Fusidic acid resistance protein FusB
Descriptor: FAR1, ZINC ION
Authors:Guo, X, Peisker, K, Backbro, K, Chen, Y, Kiran, R.K, Sanyal, S, Selmer, M.
Deposit date:2011-12-31
Release date:2012-03-07
Last modified:2012-07-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and Function of Fusb: An Elongation Factor G-Binding Fusidic Acid Resistance Protein Active in Ribosomal Translocation and Recycling
Open Biol., 2, 2012
3ZZ0
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BU of 3zz0 by Molmil
Crystal structure of ribosomal elongation factor (EF)-G from Staphylococcus aureus with a fusidic acid hyper-sensitivity mutation M16I
Descriptor: Elongation factor G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-08-30
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of elongation factor-G-mediated fusidic acid resistance and fitness compensation in Staphylococcus aureus.
J. Biol. Chem., 287, 2012
3ZZT
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BU of 3zzt by Molmil
Crystal structure of Staphylococcus aureus elongation factor G with a fusidic-acid-resistant mutation F88L
Descriptor: ELONGATION FACTOR G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Elongation Factor-G-Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
3ZZU
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BU of 3zzu by Molmil
Crystal structure of Staphylococcus aureus elongation factor G with mutations M16I and F88L
Descriptor: ELONGATION FACTOR G
Authors:Koripella, R.K, Chen, Y, Selmer, M, Sanyal, S.
Deposit date:2011-09-05
Release date:2012-07-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Mechanism of Elongation Factor-G Mediated Fusidic Acid Resistance and Fitness Compensation in Staphylococcus Aureus.
J.Biol.Chem., 287, 2012
4CSU
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BU of 4csu by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with ObgE
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ...
Authors:Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N.
Deposit date:2014-03-10
Release date:2014-06-04
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
5XYU
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BU of 5xyu by Molmil
Small subunit of Mycobacterium smegmatis ribosome
Descriptor: 16S RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Li, Z, Zhang, Y, Zheng, L, Ge, X, Sanyal, S, Gao, N.
Deposit date:2017-07-10
Release date:2017-09-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
5XYM
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BU of 5xym by Molmil
Large subunit of Mycobacterium smegmatis
Descriptor: 23S RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Li, Z, Ge, X, Zhang, Y, Zheng, L, Sanyal, S, Gao, N.
Deposit date:2017-07-09
Release date:2017-09-27
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018

 

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