Author results

3MPG
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DIHYDROOROTASE FROM BACILLUS ANTHRACIS
Descriptor:Dihydroorotase, ZINC ION
Authors:Santarsiero, B.D., Mehboob, S., Johnson, M.E.
Deposit date:2010-04-26
Release date:2010-11-10
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of dihydroorotase from Bacillus anthracis at 2.6A resolution.
Acta Crystallogr.,Sect.F, 66, 2010
1B71
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RUBRERYTHRIN
Descriptor:PROTEIN (RUBRERYTHRIN), FE (III) ION, ZINC ION
Authors:Sieker, L.C., Holmes, M., Le Trong, I., Turley, S., Santarsiero, B.D., Liu, M.-Y., Legall, J., Stenkamp, R.E.
Deposit date:1999-01-26
Release date:2000-01-26
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Alternative metal-binding sites in rubrerythrin.
Nat.Struct.Biol., 6, 1999
1RTP
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REFINED X-RAY STRUCTURE OF RAT PARVALBUMIN, A MAMMALIAN ALPHA-LINEAGE PARVALBUMIN, AT 2.0 A RESOLUTION
Descriptor:ALPHA-PARVALBUMIN, CALCIUM ION
Authors:Mcphalen, C.A., Sielecki, A.R., Santarsiero, B.D., James, M.N.G.
Deposit date:1993-05-14
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined crystal structure of rat parvalbumin, a mammalian alpha-lineage parvalbumin, at 2.0 A resolution.
J.Mol.Biol., 235, 1994
1T5A
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HUMAN PYRUVATE KINASE M2
Descriptor:Pyruvate kinase, M2 isozyme, BETA-FRUCTOSE-1,6-DIPHOSPHATE, ...
Authors:Dombrauckas, J.D., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2004-05-03
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.
Biochemistry, 44, 2005
2ALV
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X-RAY STRUCTURAL ANALYSIS OF SARS CORONAVIRUS 3CL PROTEINASE IN COMPLEX WITH DESIGNED ANTI-VIRAL INHIBITORS
Descriptor:Replicase polyprotein 1ab, N-((3S,6R)-6-((S,E)-4-ETHOXYCARBONYL-1-((S)-2-OXOPYRROLIDIN-3-YL)BUT-3-EN-2-YLCARBAMOYL)-2,9-DIMETHYL-4-OXODEC-8-EN-3-YL)-5-METHYLISOXAZOLE-3-CARBOXAMIDE
Authors:Ghosh, A.K., Xi, K., Ratia, K., Santarsiero, B.D., Fu, W., Harcourt, B.H., Rota, P.A., Baker, S.C., Johnson, M.E., Mesecar, A.D.
Deposit date:2005-08-08
Release date:2006-08-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors.
J.Med.Chem., 48, 2005
2DWU
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CRYSTAL STRUCTURE OF GLUTAMATE RACEMASE ISOFORM RACE1 FROM BACILLUS ANTHRACIS
Descriptor:Glutamate racemase, POTASSIUM ION, D-GLUTAMIC ACID, ...
Authors:Mehboob, S., Santarsiero, B.D., Johnson, M.E.
Deposit date:2006-08-17
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Analysis of Two Glutamate Racemase Isozymes from Bacillus anthracis and Implications for Inhibitor Design
J.Mol.Biol., 371, 2007
2FE8
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SARS CORONAVIRUS PAPAIN-LIKE PROTEASE: STRUCTURE OF A VIRAL DEUBIQUITINATING ENZYME
Descriptor:Replicase polyprotein 1ab, ZINC ION, BROMIDE ION, ...
Authors:Ratia, K., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2005-12-15
Release date:2006-03-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme
Proc.Natl.Acad.Sci.Usa, 103, 2006
2GZM
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CRYSTAL STRUCTURE OF THE GLUTAMATE RACEMASE FROM BACILLUS ANTHRACIS
Descriptor:Glutamate racemase, D-GLUTAMIC ACID
Authors:May, M., Santarsiero, B.D., Johnson, M.E., Mesecar, A.D.
Deposit date:2006-05-11
Release date:2007-05-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design.
J.Mol.Biol., 371, 2007
2ID7
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1.75 A STRUCTURE OF T87I PHOSPHONO-CHEY
Descriptor:Chemotaxis protein cheY
Authors:Halkides, C.J., Haas, R.M., McAdams, K.A., Casper, E.S., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2006-09-14
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides.
Arch.Biochem.Biophys., 479, 2008
2ID9
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1.85 A STRUCTURE OF T87I/Y106W PHOSPHONO-CHEY
Descriptor:Chemotaxis protein cheY
Authors:Halkides, C.J., Haas, R.M., McAdams, K.A., Casper, E.S., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2006-09-14
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides.
Arch.Biochem.Biophys., 479, 2008
2IDM
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2.00 A STRUCTURE OF T87I/Y106W PHOSPHONO-CHEY
Descriptor:Chemotaxis protein cheY, ACETATE ION
Authors:Halkides, C.J., Haas, R.M., McAdams, K.A., Casper, E.S., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2006-09-15
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides.
Arch.Biochem.Biophys., 479, 2008
2QIO
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X-RAY STRUCTURE OF ENOYL-ACYL CARRIER PROTEIN REDUCTASE FROM BACILLUS ANTHRACIS WITH TRICLOSAN
Descriptor:Enoyl-(Acyl-carrier-protein) reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
Authors:Klein, G.M., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2007-07-05
Release date:2008-07-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase.
Chemmedchem, 3, 2008
2QTM
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CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE
Descriptor:Nicotinate (Nicotinamide) nucleotide adenylyltransferase, COBALT (II) ION, GLYCEROL
Authors:Sershon, V.C., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2007-08-02
Release date:2008-07-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis.
J.Mol.Biol., 385, 2009
2QTN
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CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE
Descriptor:Nicotinate (Nicotinamide) nucleotide adenylyltransferase, MAGNESIUM ION, GLYCEROL, ...
Authors:Sershon, V.C., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2007-08-02
Release date:2008-07-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis.
J.Mol.Biol., 385, 2009
2QTR
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CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE
Descriptor:Nicotinate (Nicotinamide) nucleotide adenylyltransferase, SULFATE ION, 1-[(2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-3-carboxypyridinium
Authors:Sershon, V.C., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2007-08-02
Release date:2008-07-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis.
J.Mol.Biol., 385, 2009
2QWX
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CRYSTAL STRUCTURE OF QUINONE REDUCTASE II
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Calamini, B., Santarsiero, B.D., Boutin, J.A., Mesecar, A.D.
Deposit date:2007-08-10
Release date:2008-04-29
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2QX4
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CRYSTAL STRUCTURE OF QUINONE REDUCTASE II
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
Authors:Calamini, B., Santarsiero, B.D., Boutin, J.A., Mesecar, A.D.
Deposit date:2007-08-10
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2QX6
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CRYSTAL STRUCTURE OF QUINONE REDUCTASE II
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
Authors:Calamini, B., Santarsiero, B.D., Boutin, J.A., Mesecar, A.D.
Deposit date:2007-08-10
Release date:2008-09-09
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2QX8
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CRYSTAL STRUCTURE OF QUINONE REDUCTASE II
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
Authors:Calamini, B., Santarsiero, B.D., Boutin, J.A., Mesecar, A.D.
Deposit date:2007-08-10
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2QX9
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CRYSTAL STRUCTURE OF QUINONE REDUCTASE II
Descriptor:Ribosyldihydronicotinamide dehydrogenase [quinone], FLAVIN-ADENINE DINUCLEOTIDE, N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
Authors:Calamini, B., Santarsiero, B.D., Boutin, J.A., Mesecar, A.D.
Deposit date:2007-08-10
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.
Biochem.J., 413, 2008
2ZC1
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ORGANOPHOSPHORUS HYDROLASE FROM DEINOCOCCUS RADIODURANS
Descriptor:Phosphotriesterase, BROMIDE ION, COBALT (II) ION
Authors:Larsen, S.D., Hawwa, R., Ratia, K., Santarsiero, B.D., Mesecar, A.D.
Deposit date:2007-11-02
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-Ray Structural Insights into a Phosphotriesterase
to be published
3F31
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF ALPHAII-SPECTRIN TETRAMERIZATION DOMAIN
Descriptor:Spectrin alpha chain, brain
Authors:Mehboob, S., Santarsiero, B.D., Long, F., Witek, M., Fung, L.W.
Deposit date:2008-10-30
Release date:2009-10-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation.
J.Biol.Chem., 285, 2010
3FCT
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MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN
Descriptor:PROTEIN (METAL CHELATASE CATALYTIC ANTIBODY), CADMIUM ION, CALCIUM ION, ...
Authors:Romesberg, F.E., Santarsiero, B.D., Barnes, D., Yin, J., Spiller, B., Schultz, P.G., Stevens, R.C.
Deposit date:1999-06-13
Release date:1999-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and kinetic evidence for strain in biological catalysis.
Biochemistry, 37, 1998
3NRC
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CRYSTAL STRUCTURE OF THE FRANCISELLA TULARENSIS ENOYL-ACYL CARRIER PROTEIN REDUCTASE (FABI) IN COMPLEX WITH NAD+ AND TRICLOSAN
Descriptor:Enoyl-[acyl-carrier-protein] reductase (NADH), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
Authors:Mehboob, S., Santarsiero, B.D., Truong, K., Johnson, M.E.
Deposit date:2010-06-30
Release date:2010-11-10
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan.
Acta Crystallogr.,Sect.F, 66, 2010
3Q2O
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CRYSTAL STRUCTURE OF PURK: N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE
Descriptor:Phosphoribosylaminoimidazole carboxylase, ATPase subunit, MAGNESIUM ION
Authors:Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E.
Deposit date:2010-12-20
Release date:2011-10-26
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure of N(5)-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis.
Acta Crystallogr.,Sect.D, 67, 2011
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