Author results

2X79
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INWARD FACING CONFORMATION OF MHP1
Descriptor:HYDANTOIN TRANSPORT PROTEIN
Authors:Shimamura, T., Weyand, S., Beckstein, O., Rutherford, N.G., Hadden, J.M., Sharples, D., Sansom, M.S.P., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2010-02-25
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
2XUT
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CRYSTAL STRUCTURE OF A PROTON DEPENDENT OLIGOPEPTIDE (POT) FAMILY TRANSPORTER.
Descriptor:PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
Authors:Newstead, S., Drew, D., Cameron, A.D., Postis, V.L., Xia, X., Fowler, P.W., Ingram, J.C., Carpenter, E.P., Sansom, M.S.P., McPherson, M.J., Baldwin, S.A., Iwata, S.
Deposit date:2010-10-21
Release date:2010-12-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
3ZRS
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X-RAY CRYSTAL STRUCTURE OF A KIRBAC POTASSIUM CHANNEL HIGHLIGHTS A MECHANISM OF CHANNEL OPENING AT THE BUNDLE-CROSSING GATE.
Descriptor:ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION
Authors:Bavro, V.N., De Zorzi, R., Schmidt, M.R., Muniz, J.R.C., Zubcevic, L., Sansom, M.S.P., Venien-Bryan, C., Tucker, S.J.
Deposit date:2011-06-17
Release date:2012-01-11
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
4BBK
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE KINDLIN-1 PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:FERMITIN FAMILY HOMOLOG 1, GLYCEROL
Authors:Yates, L.A., Lumb, C.N., Brahme, N.N., Zalyte, R., Bird, L.E., De Colibus, L., Owens, R.J., Calderwood, D.A., Sansom, M.S.P., Gilbert, R.J.C.
Deposit date:2012-09-25
Release date:2012-11-14
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
5FTT
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OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR)
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FTU
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TETRAMERIC COMPLEX OF LATROPHILIN 3, UNC5D AND FLRT2
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (6.01 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
4B4A
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STRUCTURE OF THE TATC CORE OF THE TWIN ARGININE PROTEIN TRANSLOCATION SYSTEM
Descriptor:SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC, Lauryl Maltose Neopentyl Glycol
Authors:Rollauer, S.E., Tarry, M.J., Jaaskelainen, M., Graham, J.E., Jaeger, F., Krehenbrink, M., Roversi, P., McDowell, M.A., Stansfeld, P.J., Johnson, S., Liu, S.M., Lukey, M.J., Marcoux, J., Robinson, C.V., Sansom, M.S., Palmer, T., Hogbom, M., Berks, B.C., Lea, S.M.
Deposit date:2012-07-30
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the Tatc Core of the Twin-Arginine Protein Transport System.
Nature, 49, 2012
4LP8
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A NOVEL OPEN-STATE CRYSTAL STRUCTURE OF THE PROKARYOTIC INWARD RECTIFIER KIRBAC3.1
Descriptor:Inward rectifier potassium channel Kirbac3.1, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ...
Authors:Zubcevic, L., Bavro, V.N., Muniz, J.R.C., Schmidt, M.R., Wang, S., De Zorzi, R., Venien-Bryan, C., Sansom, M.S.P., Nichols, C.G., Tucker, S.J.
Deposit date:2013-07-15
Release date:2013-11-20
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains.
J.Biol.Chem., 289, 2014
5L7D
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STRUCTURE OF HUMAN SMOOTHENED IN COMPLEX WITH CHOLESTEROL
Descriptor:Smoothened homolog,Soluble cytochrome b562,Smoothened homolog, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL, ...
Authors:Byrne, E.F.X., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.P., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.
Deposit date:2016-06-03
Release date:2016-07-20
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
5L7I
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STRUCTURE OF HUMAN SMOOTHENED IN COMPLEX WITH VISMODEGIB
Descriptor:Smoothened homolog,Soluble cytochrome b562,Smoothened homolog, N-ACETYL-D-GLUCOSAMINE, 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, ...
Authors:Byrne, E.X.B., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.F., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.
Deposit date:2016-06-03
Release date:2016-07-20
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
2VR0
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CRYSTAL STRUCTURE OF CYTOCHROME C NITRITE REDUCTASE NRFHA COMPLEX BOUND TO THE HQNO INHIBITOR
Descriptor:CYTOCHROME C NITRITE REDUCTASE, CATALYTIC SUBUNIT NFRA, NAPC/NIRT CYTOCHROME C FAMILY PROTEIN, ...
Authors:Rodrigues, M.L., Archer, M.
Deposit date:2008-03-24
Release date:2008-06-03
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Quinol Oxidation by C-Type Cytochromes: Structural Characterization of the Menaquinol Binding Site of Nrfha.
J.Mol.Biol., 381, 2008
2YPT
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 MUTANT (E336A) IN COMPLEX WITH A SYNTHETIC CSIM TETRAPEPTIDE FROM THE C-TERMINUS OF PRELAMIN A
Descriptor:CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
Authors:Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Savitsky, P., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2012-11-01
Release date:2012-12-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
3ZDQ
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM)
Descriptor:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL, GLYCINE, ...
Authors:Pike, A.C.W., Shintre, C.A., Krojer, T., von Delft, F., Vollmar, M., Mukhopadhyay, S., Burgess-Brown, N., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Carpenter, E.P.
Deposit date:2012-11-30
Release date:2013-01-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AFK
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMONAS AERUGINOSA, PAO1
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, CALCIUM ION, CITRATE ANION, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-01-19
Release date:2013-02-06
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4AW6
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 (FACE1)
Descriptor:CAAX PRENYL PROTEASE 1 HOMOLOG, ZINC ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Authors:Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2012-05-31
Release date:2012-07-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4AYT
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
Descriptor:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, GLYCINE, MAGNESIUM ION, ...
Authors:Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYX
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
Descriptor:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, GLYCINE, MAGNESIUM ION, ...
Authors:Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AZL
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1, CRYSTAL FORM 2.
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CALCIUM ION, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-06-26
Release date:2013-07-03
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4B61
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1. CRYSTAL FORM 3.
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, LAURYL DIMETHYLAMINE-N-OXIDE, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-08-08
Release date:2013-07-17
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4BW5
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CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1)
Descriptor:POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, CADMIUM ION, ...
Authors:Pike, A.C.W., Dong, Y.Y., Dong, L., Quigley, A., Shrestha, L., Mukhopadhyay, S., Strain-Damerell, C., Goubin, S., Grieben, M., Shintre, C.A., Mackenzie, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N., Carpenter, E.P.
Deposit date:2013-06-30
Release date:2013-07-31
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
Science, 347, 2015
4UXW
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STRUCTURE OF DELTA4-DGKA-APO IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Li, D., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXX
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STRUCTURE OF DELTA4-DGKA WITH AMPPCP IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, CHLORIDE ION, SODIUM ION, ...
Authors:Li, D., Vogeley, L., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXZ
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STRUCTURE OF DELTA7-DGKA-SYN IN 7.9 MAG TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UYO
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STRUCTURE OF DELTA7-DGKA IN 7.9 MAG BY SERIAL FEMTOSECOND CRYSTATALLOGRAPHY TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Other, O., Caffrey, M.
Deposit date:2014-09-02
Release date:2015-09-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
5AJI
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MSCS D67R1 HIGH RESOLUTION
Descriptor:SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL, N-OCTANE, HEXANE, ...
Authors:Naismith, J.H., Pliotas, C.
Deposit date:2015-02-24
Release date:2015-07-08
Last modified:2015-12-23
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The Role of Lipids in Mechanosensation.
Nat.Struct.Mol.Biol., 22, 2015
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