Author results

2X79
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INWARD FACING CONFORMATION OF MHP1
分子名称:HYDANTOIN TRANSPORT PROTEIN
著者Shimamura, T., Weyand, S., Beckstein, O., Rutherford, N.G., Hadden, J.M., Sharples, D., Sansom, M.S.P., Iwata, S., Henderson, P.J.F., Cameron, A.D.
登録日2010-02-25
公開日2010-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
2XUT
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CRYSTAL STRUCTURE OF A PROTON DEPENDENT OLIGOPEPTIDE (POT) FAMILY TRANSPORTER.
分子名称:PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
著者Newstead, S., Drew, D., Cameron, A.D., Postis, V.L., Xia, X., Fowler, P.W., Ingram, J.C., Carpenter, E.P., Sansom, M.S.P., McPherson, M.J., Baldwin, S.A., Iwata, S.
登録日2010-10-21
公開日2010-12-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.62 Å)
主引用文献Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
3ZRS
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X-RAY CRYSTAL STRUCTURE OF A KIRBAC POTASSIUM CHANNEL HIGHLIGHTS A MECHANISM OF CHANNEL OPENING AT THE BUNDLE-CROSSING GATE.
分子名称:ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION
著者Bavro, V.N., De Zorzi, R., Schmidt, M.R., Muniz, J.R.C., Zubcevic, L., Sansom, M.S.P., Venien-Bryan, C., Tucker, S.J.
登録日2011-06-17
公開日2012-01-11
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
4BBK
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE KINDLIN-1 PLECKSTRIN HOMOLOGY DOMAIN
分子名称:FERMITIN FAMILY HOMOLOG 1, GLYCEROL
著者Yates, L.A., Lumb, C.N., Brahme, N.N., Zalyte, R., Bird, L.E., De Colibus, L., Owens, R.J., Calderwood, D.A., Sansom, M.S.P., Gilbert, R.J.C.
登録日2012-09-25
公開日2012-11-14
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
5FTT
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OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR)
分子名称:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
著者Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
登録日2016-01-15
公開日2016-05-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FTU
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TETRAMERIC COMPLEX OF LATROPHILIN 3, UNC5D AND FLRT2
分子名称:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
著者Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
登録日2016-01-15
公開日2016-05-04
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (6.01 Å)
主引用文献Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
4B4A
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STRUCTURE OF THE TATC CORE OF THE TWIN ARGININE PROTEIN TRANSLOCATION SYSTEM
分子名称:SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC, Lauryl Maltose Neopentyl Glycol
著者Rollauer, S.E., Tarry, M.J., Jaaskelainen, M., Graham, J.E., Jaeger, F., Krehenbrink, M., Roversi, P., McDowell, M.A., Stansfeld, P.J., Johnson, S., Liu, S.M., Lukey, M.J., Marcoux, J., Robinson, C.V., Sansom, M.S., Palmer, T., Hogbom, M., Berks, B.C., Lea, S.M.
登録日2012-07-30
公開日2012-12-05
最終更新日2012-12-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Tatc Core of the Twin-Arginine Protein Transport System.
Nature, 49, 2012
4LP8
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A NOVEL OPEN-STATE CRYSTAL STRUCTURE OF THE PROKARYOTIC INWARD RECTIFIER KIRBAC3.1
分子名称:Inward rectifier potassium channel Kirbac3.1, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ...
著者Zubcevic, L., Bavro, V.N., Muniz, J.R.C., Schmidt, M.R., Wang, S., De Zorzi, R., Venien-Bryan, C., Sansom, M.S.P., Nichols, C.G., Tucker, S.J.
登録日2013-07-15
公開日2013-11-20
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains.
J.Biol.Chem., 289, 2014
5L7D
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STRUCTURE OF HUMAN SMOOTHENED IN COMPLEX WITH CHOLESTEROL
分子名称:Smoothened homolog,Soluble cytochrome b562,Smoothened homolog, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL, ...
著者Byrne, E.F.X., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.P., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.
登録日2016-06-03
公開日2016-07-20
最終更新日2016-08-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
5L7I
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STRUCTURE OF HUMAN SMOOTHENED IN COMPLEX WITH VISMODEGIB
分子名称:Smoothened homolog,Soluble cytochrome b562,Smoothened homolog, N-ACETYL-D-GLUCOSAMINE, 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, ...
著者Byrne, E.X.B., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.F., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.
登録日2016-06-03
公開日2016-07-20
最終更新日2016-08-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
2VR0
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CRYSTAL STRUCTURE OF CYTOCHROME C NITRITE REDUCTASE NRFHA COMPLEX BOUND TO THE HQNO INHIBITOR
分子名称:CYTOCHROME C NITRITE REDUCTASE, CATALYTIC SUBUNIT NFRA, NAPC/NIRT CYTOCHROME C FAMILY PROTEIN, ...
著者Rodrigues, M.L., Archer, M.
登録日2008-03-24
公開日2008-06-03
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Quinol Oxidation by C-Type Cytochromes: Structural Characterization of the Menaquinol Binding Site of Nrfha.
J.Mol.Biol., 381, 2008
2YPT
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 MUTANT (E336A) IN COMPLEX WITH A SYNTHETIC CSIM TETRAPEPTIDE FROM THE C-TERMINUS OF PRELAMIN A
分子名称:CAAX PRENYL PROTEASE 1 HOMOLOG, PRELAMIN-A/C, ZINC ION
著者Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Savitsky, P., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
登録日2012-11-01
公開日2012-12-05
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
3ZDQ
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (NUCLEOTIDE-FREE FORM)
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL, GLYCINE, ...
著者Pike, A.C.W., Shintre, C.A., Krojer, T., von Delft, F., Vollmar, M., Mukhopadhyay, S., Burgess-Brown, N., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-11-30
公開日2013-01-23
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AFK
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMONAS AERUGINOSA, PAO1
分子名称:ALGINATE PRODUCTION PROTEIN ALGE, CALCIUM ION, CITRATE ANION, ...
著者Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
登録日2012-01-19
公開日2013-02-06
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4AW6
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEAR MEMBRANE ZINC METALLOPROTEASE ZMPSTE24 (FACE1)
分子名称:CAAX PRENYL PROTEASE 1 HOMOLOG, ZINC ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
著者Pike, A.C.W., Dong, Y.Y., Quigley, A., Dong, L., Cooper, C.D.O., Chaikuad, A., Goubin, S., Shrestha, L., Li, Q., Mukhopadhyay, S., Yang, J., Xia, X., Shintre, C.A., Barr, A.J., Berridge, G., Chalk, R., Bray, J.E., von Delft, F., Bullock, A., Bountra, C., Arrowsmith, C.H., Edwards, A., Burgess-Brown, N., Carpenter, E.P.
登録日2012-05-31
公開日2012-07-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Structural Basis of Zmpste24-Dependent Laminopathies.
Science, 339, 2013
4AYT
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, GLYCINE, MAGNESIUM ION, ...
著者Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYX
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
分子名称:ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, GLYCINE, MAGNESIUM ION, ...
著者Pike, A.C.W., Shintre, C.A., Li, Q., Kim, J., von Delft, F., Barr, A.J., Das, S., Chaikuad, A., Xia, X., Quigley, A., Dong, Y., Dong, L., Krojer, T., Vollmar, M., Muniz, J.R.C., Bray, J.E., Berridge, G., Chalk, R., Gileadi, O., Burgess-Brown, N., Shrestha, L., Goubin, S., Yang, J., Mahajan, P., Mukhopadhyay, S., Bullock, A.N., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AZL
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1, CRYSTAL FORM 2.
分子名称:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CALCIUM ION, ...
著者Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
登録日2012-06-26
公開日2013-07-03
最終更新日2015-09-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4B61
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1. CRYSTAL FORM 3.
分子名称:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, LAURYL DIMETHYLAMINE-N-OXIDE, ...
著者Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
登録日2012-08-08
公開日2013-07-17
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4BW5
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CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1)
分子名称:POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, CADMIUM ION, ...
著者Pike, A.C.W., Dong, Y.Y., Dong, L., Quigley, A., Shrestha, L., Mukhopadhyay, S., Strain-Damerell, C., Goubin, S., Grieben, M., Shintre, C.A., Mackenzie, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N., Carpenter, E.P.
登録日2013-06-30
公開日2013-07-31
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
Science, 347, 2015
4UXW
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STRUCTURE OF DELTA4-DGKA-APO IN 9.9 MAG
分子名称:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
著者Li, D., Pye, V.E., Aragao, D., Caffrey, M.
登録日2014-08-27
公開日2015-09-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXX
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STRUCTURE OF DELTA4-DGKA WITH AMPPCP IN 9.9 MAG
分子名称:DIACYLGLYCEROL KINASE, CHLORIDE ION, SODIUM ION, ...
著者Li, D., Vogeley, L., Caffrey, M.
登録日2014-08-27
公開日2015-09-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXZ
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STRUCTURE OF DELTA7-DGKA-SYN IN 7.9 MAG TO 2.18 ANGSTROM RESOLUTION
分子名称:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
著者Li, D., Howe, N., Caffrey, M.
登録日2014-08-27
公開日2015-09-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UYO
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STRUCTURE OF DELTA7-DGKA IN 7.9 MAG BY SERIAL FEMTOSECOND CRYSTATALLOGRAPHY TO 2.18 ANGSTROM RESOLUTION
分子名称:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
著者Li, D., Howe, N., Other, O., Caffrey, M.
登録日2014-09-02
公開日2015-09-30
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
5AJI
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MSCS D67R1 HIGH RESOLUTION
分子名称:SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL, N-OCTANE, HEXANE, ...
著者Naismith, J.H., Pliotas, C.
登録日2015-02-24
公開日2015-07-08
最終更新日2015-12-23
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The Role of Lipids in Mechanosensation.
Nat.Struct.Mol.Biol., 22, 2015
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