Author results

3G04
  • Download 3g04
  • View 3g04
Molmil generated image of 3g04
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A THYROID-STIMULATING AUTOANTIBODY
分子名称:HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN, HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN, Thyrotropin receptor, ...
著者Sanders, J., Chirgadze, D.Y., Sanders, P., Baker, S., Sullivan, A., Bhardwaja, A., Bolton, J., Reeve, M., Nakatake, N., Evans, M., Richards, T., Powell, M., Miguel, R.N., Blundell, T.L., Furmaniak, J., Smith, B.R.
登録日2009-01-27
公開日2009-08-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Thyroid, 17, 2007
2XWT
  • Download 2xwt
  • View 2xwt
Molmil generated image of 2xwt
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
分子名称:THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN, THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 LIGHT CHAIN, THYROTROPIN RECEPTOR, ...
著者Sanders, J., Sanders, P., Young, S., Kabelis, K., Baker, S., Sullivan, A., Evans, M., Clark, J., Wilmot, J., Hu, X., Roberts, E., Powell, M., Nunez Miguel, R., Furmaniak, J., Rees Smith, B.
登録日2010-11-05
公開日2011-03-09
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
J.Mol.Endocrinol., 46, 2011
6BYB
  • Download 6byb
  • View 6byb
Molmil generated image of 6byb
CRYSTAL STRUCTURE OF L3MBTL1 MBT DOMAIN WITH MBK14970
分子名称:Lethal(3)malignant brain tumor-like protein 1, (S)-N-(cyclopropylmethyl)-N~2~-methyl-N-[2-methyl-2-(1-methylpiperidin-4-yl)propyl]alaninamide, 1,2-ETHANEDIOL, ...
著者DONG, A., DOBROVETSKY, E., NICHOLSON, B., COX, C., FISCHER, C., ARMACOST, K., SANDERS, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)
登録日2017-12-20
公開日2018-01-24
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of L3MBTL1 MBT Domain with MBK14970
to be published
3KU4
  • Download 3ku4
  • View 3ku4
Molmil generated image of 3ku4
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
分子名称:Uridine phosphorylase, SULFATE ION
著者Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2009-11-26
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KUK
  • Download 3kuk
  • View 3kuk
Molmil generated image of 3kuk
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
分子名称:Uridine phosphorylase, SULFATE ION, 2'-DEOXYURIDINE
著者Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2009-11-27
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.783 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVR
  • Download 3kvr
  • View 3kvr
Molmil generated image of 3kvr
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
分子名称:Uridine phosphorylase, 5-FLUOROURACIL, SULFATE ION, ...
著者Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2009-11-30
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVV
  • Download 3kvv
  • View 3kvv
Molmil generated image of 3kvv
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
分子名称:Uridine phosphorylase, 5-FLUOROURACIL, SULFATE ION, ...
著者Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2009-11-30
公開日2010-04-28
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVY
  • Download 3kvy
  • View 3kvy
Molmil generated image of 3kvy
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
分子名称:Uridine Phosphorylase, SULFATE ION, URACIL, ...
著者Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2009-11-30
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
4ESW
  • Download 4esw
  • View 4esw
Molmil generated image of 4esw
CRYSTAL STRUCTURE OF C. ALBICANS THI5 H66G MUTANT
分子名称:Pyrimidine biosynthesis enzyme THI13, CITRIC ACID
著者Fenwick, M.K., Huang, S., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2012-04-23
公開日2012-09-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
4ESX
  • Download 4esx
  • View 4esx
Molmil generated image of 4esx
CRYSTAL STRUCTURE OF C. ALBICANS THI5 COMPLEXED WITH PLP
分子名称:Pyrimidine biosynthesis enzyme THI13
著者Huang, S., Fenwick, M.K., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
登録日2012-04-23
公開日2012-09-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
5NMI
  • Download 5nmi
  • View 5nmi
Molmil generated image of 5nmi
CYTOCHROME BC1 BOUND TO THE INHIBITOR MJM170
分子名称:Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 2, ...
著者Capper, N.J., Antonyuk, S.V., Hasnain, S.S.
登録日2017-04-05
公開日2017-06-14
最終更新日2018-12-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Sci Rep, 6, 2016
1YX3
  • Download 1yx3
  • View 1yx3
Molmil generated image of 1yx3
NMR STRUCTURE OF ALLOCHROMATIUM VINOSUM DSRC: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OP4
分子名称:hypothetical protein DsrC
著者Cort, J.R., Dahl, C., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)
登録日2005-02-19
公開日2005-04-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Allochromatium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation.
J.Mol.Biol., 382, 2008