Author results

3G04
  • Download 3g04
  • View 3g04
Molmil generated image of 3g04
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A THYROID-STIMULATING AUTOANTIBODY
Descriptor:HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN, HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN, Thyrotropin receptor, ...
Authors:Sanders, J., Chirgadze, D.Y., Sanders, P., Baker, S., Sullivan, A., Bhardwaja, A., Bolton, J., Reeve, M., Nakatake, N., Evans, M., Richards, T., Powell, M., Miguel, R.N., Blundell, T.L., Furmaniak, J., Smith, B.R.
Deposit date:2009-01-27
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Thyroid, 17, 2007
2XWT
  • Download 2xwt
  • View 2xwt
Molmil generated image of 2xwt
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
Descriptor:THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN, THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 LIGHT CHAIN, THYROTROPIN RECEPTOR, ...
Authors:Sanders, J., Sanders, P., Young, S., Kabelis, K., Baker, S., Sullivan, A., Evans, M., Clark, J., Wilmot, J., Hu, X., Roberts, E., Powell, M., Nunez Miguel, R., Furmaniak, J., Rees Smith, B.
Deposit date:2010-11-05
Release date:2011-03-09
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
J.Mol.Endocrinol., 46, 2011
6BYB
  • Download 6byb
  • View 6byb
Molmil generated image of 6byb
CRYSTAL STRUCTURE OF L3MBTL1 MBT DOMAIN WITH MBK14970
Descriptor:Lethal(3)malignant brain tumor-like protein 1, (S)-N-(cyclopropylmethyl)-N~2~-methyl-N-[2-methyl-2-(1-methylpiperidin-4-yl)propyl]alaninamide, 1,2-ETHANEDIOL, ...
Authors:DONG, A., DOBROVETSKY, E., NICHOLSON, B., COX, C., FISCHER, C., ARMACOST, K., SANDERS, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., Structural Genomics Consortium (SGC)
Deposit date:2017-12-20
Release date:2018-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of L3MBTL1 MBT Domain with MBK14970
to be published
3KU4
  • Download 3ku4
  • View 3ku4
Molmil generated image of 3ku4
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
Descriptor:Uridine phosphorylase, SULFATE ION
Authors:Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2009-11-26
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KUK
  • Download 3kuk
  • View 3kuk
Molmil generated image of 3kuk
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
Descriptor:Uridine phosphorylase, SULFATE ION, 2'-DEOXYURIDINE
Authors:Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2009-11-27
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.783 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVR
  • Download 3kvr
  • View 3kvr
Molmil generated image of 3kvr
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
Descriptor:Uridine phosphorylase, 5-FLUOROURACIL, SULFATE ION, ...
Authors:Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2009-11-30
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVV
  • Download 3kvv
  • View 3kvv
Molmil generated image of 3kvv
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
Descriptor:Uridine phosphorylase, 5-FLUOROURACIL, SULFATE ION, ...
Authors:Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2009-11-30
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
3KVY
  • Download 3kvy
  • View 3kvy
Molmil generated image of 3kvy
TRAPPING OF AN OXOCARBENIUM ION INTERMEDIATE IN UP CRYSTALS
Descriptor:Uridine Phosphorylase, SULFATE ION, URACIL, ...
Authors:Paul, D., O'Leary, S., Rajashankar, K., Bu, W., Toms, A., Settembre, E., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2009-11-30
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Glycal formation in crystals of uridine phosphorylase.
Biochemistry, 49, 2010
4ESW
  • Download 4esw
  • View 4esw
Molmil generated image of 4esw
CRYSTAL STRUCTURE OF C. ALBICANS THI5 H66G MUTANT
Descriptor:Pyrimidine biosynthesis enzyme THI13, CITRIC ACID
Authors:Fenwick, M.K., Huang, S., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
4ESX
  • Download 4esx
  • View 4esx
Molmil generated image of 4esx
CRYSTAL STRUCTURE OF C. ALBICANS THI5 COMPLEXED WITH PLP
Descriptor:Pyrimidine biosynthesis enzyme THI13
Authors:Huang, S., Fenwick, M.K., Zhang, Y., Lai, R., Hazra, A., Rajashankar, K., Philmus, B., Kinsland, C., Sanders, J., Begley, T.P., Ealick, S.E.
Deposit date:2012-04-23
Release date:2012-09-19
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
J.Am.Chem.Soc., 134, 2012
5NMI
  • Download 5nmi
  • View 5nmi
Molmil generated image of 5nmi
CYTOCHROME BC1 BOUND TO THE INHIBITOR MJM170
Descriptor:Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 2, ...
Authors:Capper, N.J., Antonyuk, S.V., Hasnain, S.S.
Deposit date:2017-04-05
Release date:2017-06-14
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Sci Rep, 6, 2016
1YX3
  • Download 1yx3
  • View 1yx3
Molmil generated image of 1yx3
NMR STRUCTURE OF ALLOCHROMATIUM VINOSUM DSRC: NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OP4
Descriptor:hypothetical protein DsrC
Authors:Cort, J.R., Dahl, C., Montelione, G.T., Kennedy, M.A., Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-02-19
Release date:2005-04-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Allochromatium vinosum DsrC: solution-state NMR structure, redox properties, and interaction with DsrEFH, a protein essential for purple sulfur bacterial sulfur oxidation.
J.Mol.Biol., 382, 2008