Author results

2ERY
  • Download 2ery
  • View 2ery
Molmil generated image of 2ery
THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE
分子名称:Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2005-10-25
公開日2005-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2XYN
  • Download 2xyn
  • View 2xyn
Molmil generated image of 2xyn
HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680
分子名称:TYROSINE-PROTEIN KINASE ABL2, SODIUM ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, ...
著者Salah, E., Ugochukwu, E., Elkins, J.M., Barr, A.J., Shrestha, B., Savitsky, P., Mahajan, P., Muniz, J.R.C., Yue, W.W., Chaikuad, A., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
登録日2010-11-18
公開日2010-12-01
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structures of Abl-Related Gene (Abl2) in Complex with Imatinib, Tozasertib (Vx-680), and a Type I Inhibitor of the Triazole Carbothioamide Class.
J.Med.Chem., 54, 2011
5L6W
  • Download 5l6w
  • View 5l6w
Molmil generated image of 5l6w
STRUCTURE OF THE LIMK1-ATPGAMMAS-CFL1 COMPLEX
分子名称:LIM domain kinase 1, Cofilin-1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Salah, E., Mathea, S., Oerum, S., Newman, J.A., Tallant, C., Adamson, R., Canning, P., Beltrami, A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Bullock, A.N.
登録日2016-05-31
公開日2016-06-08
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structure Of the LIMK1-ATPgammaS-CFL1 Complex
To Be Published
3GVU
  • Download 3gvu
  • View 3gvu
Molmil generated image of 3gvu
THE CRYSTAL STRUCTURE OF HUMAN ABL2 IN COMPLEX WITH GLEEVEC
分子名称:Tyrosine-protein kinase ABL2, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
著者Ugochukwu, E., Salah, E., Barr, A., Mahajan, P., Shrestha, B., Savitsky, P., Chaikuad, A., Filippakopoulos, P., Roos, A., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
登録日2009-03-31
公開日2009-04-21
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The crystal structure of human ABL2 in complex with GLEEVEC
To be Published
2NZJ
  • Download 2nzj
  • View 2nzj
Molmil generated image of 2nzj
THE CRYSTAL STRUCTURE OF REM1 IN COMPLEX WITH GDP
分子名称:GTP-binding protein REM 1, MAGNESIUM ION, CHLORIDE ION, ...
著者Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Elkins, J.M., Soundararajan, M., Yang, X., Gorrec, F., Umeano, C., Salah, E., Burgess, N., Johansson, C., Berridge, G., Gileadi, O., Bray, J., Marsden, B., Watts, S., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-11-23
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of REM1 in complex with GDP
To be Published
2OCS
  • Download 2ocs
  • View 2ocs
Molmil generated image of 2ocs
THE CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2)
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-12-21
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2OPG
  • Download 2opg
  • View 2opg
Molmil generated image of 2opg
THE CRYSTAL STRUCTURE OF THE 10TH PDZ DOMAIN OF MPDZ
分子名称:Multiple PDZ domain protein, SODIUM ION
著者Gileadi, C., Phillips, C., Elkins, J., Papagrigoriou, E., Ugochukwu, E., Gorrec, F., Savitsky, P., Umeano, C., Berridge, G., Gileadi, O., Salah, E., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-01-29
公開日2007-02-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 10th PDZ domain of MPDZ
To be Published
2PA1
  • Download 2pa1
  • View 2pa1
Molmil generated image of 2pa1
STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM2 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN
分子名称:PDZ and LIM domain protein 2, CHLORIDE ION
著者Uppenberg, J., Shrestha, L., Elkins, J., Burgess-Brown, N., Salah, E., Bunkoczi, G., Papagrigoriou, E., Pike, A.C.W., Turnbull, A.P., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-03-27
公開日2007-05-01
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin.
To be Published
2QG1
  • Download 2qg1
  • View 2qg1
Molmil generated image of 2qg1
CRYSTAL STRUCTURE OF THE 11TH PDZ DOMAIN OF MPDZ (MUPP1)
分子名称:Multiple PDZ domain protein, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Salah, E., Phillips, C., Savitsky, P., Boisguerin, P., Oschkinat, H., Gileadi, C., Yang, X., Elkins, J.M., Ugochukwu, E., Bunkoczi, G., Uppenberg, J., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
登録日2007-06-28
公開日2007-07-24
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of the 11th PDZ domain of MPDZ (MUPP1).
To be Published
2C60
  • Download 2c60
  • View 2c60
Molmil generated image of 2c60
CRYSTAL STRUCTURE OF HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2 PHOX DOMAIN AT 1.25 A RESOLUTION
分子名称:HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3 ISOFORM 2, CALCIUM ION, GLYCEROL
著者Debreczeni, J.E., Salah, E., Papagrigoriou, E., Burgess, N., von Delft, F., Gileadi, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Knapp, S.
登録日2005-11-04
公開日2005-11-29
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal Structure of Human Mitogen-Activated Protein Kinase Kinase Kinase 3 Isoform 2 Fox Domain at 1.25 A Resolution
To be Published
2CHL
  • Download 2chl
  • View 2chl
Molmil generated image of 2chl
STRUCTURE OF CASEIN KINASE 1 GAMMA 3
分子名称:CASEIN KINASE I ISOFORM GAMMA-3, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, SULFATE ION
著者Bunkoczi, G., Salah, E., Rellos, P., Das, S., Fedorov, O., Savitsky, P., Gileadi, O., Sundstrom, M., Edwards, A., Arrowsmith, C., Ugochukwu, E., Weigelt, J., von Delft, F., Knapp, S.
登録日2006-03-15
公開日2006-03-22
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Casein Kinase 1 Gamma 3
To be Published
2ERX
  • Download 2erx
  • View 2erx
Molmil generated image of 2erx
CRYSTAL STRUCTURE OF DIRAS2 IN COMPLEX WITH GDP AND INORGANIC PHOSPHATE
分子名称:GTP-binding protein Di-Ras2, PHOSPHATE ION, MAGNESIUM ION, ...
著者Papagrigoriou, E., Yang, X., Elkins, J., Niesen, F.E., Burgess, N., Salah, E., Fedorov, O., Ball, L.J., von Delft, F., Sundstrom, M., Edwards, A., Arrowsmith, C., Weigelt, J., Doyle, D.
登録日2005-10-25
公開日2005-11-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of DiRas2
To be Published
2FE5
  • Download 2fe5
  • View 2fe5
Molmil generated image of 2fe5
THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
分子名称:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
著者Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2005-12-15
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2FN4
  • Download 2fn4
  • View 2fn4
Molmil generated image of 2fn4
THE CRYSTAL STRUCTURE OF HUMAN RAS-RELATED PROTEIN, RRAS, IN THE GDP-BOUND STATE
分子名称:Ras-related protein R-Ras, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Elkins, J.M., Gileadi, C., Burgess, N., Salah, E., Papagrigoriou, E., Debreczeni, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-01-10
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state
To be Published
2GF0
  • Download 2gf0
  • View 2gf0
Molmil generated image of 2gf0
THE CRYSTAL STRUCTURE OF THE HUMAN DIRAS1 GTPASE IN THE INACTIVE GDP BOUND STATE
分子名称:GTP-binding protein Di-Ras1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Papagrigoriou, E., Yang, X., Schoch, G., Elkins, J., Gileadi, O., Salah, E., Bray, J., Wen-Hwa, L., Fedorov, O., Niesen, F.E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-03-21
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state
To be Published
2GF2
  • Download 2gf2
  • View 2gf2
Molmil generated image of 2gf2
CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE
分子名称:3-hydroxyisobutyrate dehydrogenase
著者Papagrigoriou, E., Salah, E., Turnbull, A.P., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Gorrec, F., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-03-21
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase
To be Published
2HW5
  • Download 2hw5
  • View 2hw5
Molmil generated image of 2hw5
THE CRYSTAL STRUCTURE OF HUMAN ENOYL-COENZYME A (COA) HYDRATASE SHORT CHAIN 1, ECHS1
分子名称:Enoyl-CoA hydratase, MAGNESIUM ION, CROTONYL COENZYME A
著者Turnbull, A.P., Salah, E., Niesen, F., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Kavanagh, K., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-07-31
公開日2006-08-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
To be Published
2I9P
  • Download 2i9p
  • View 2i9p
Molmil generated image of 2i9p
CRYSTAL STRUCTURE OF HUMAN HYDROXYISOBUTYRATE DEHYDROGENASE COMPLEXED WITH NAD+
分子名称:3-hydroxyisobutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavanagh, K.L., Papagrigoriou, E., Salah, E., Lukacik, P., Smee, C., Burgess, N., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-09-06
公開日2006-09-26
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
To be Published
2IZZ
  • Download 2izz
  • View 2izz
Molmil generated image of 2izz
CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASE
分子名称:PYRROLINE-5-CARBOXYLATE REDUCTASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL
著者Pike, A.C.W., Guo, K., Kavanagh, K., Pilka, E.S., Berridge, G., Colebrook, S., Bray, J., Salah, E., Savitsky, P., Papagrigoriou, E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
登録日2006-07-31
公開日2006-08-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Human Pyrroline-5-Carboxylate Reductase
To be Published
2JC6
  • Download 2jc6
  • View 2jc6
Molmil generated image of 2jc6
CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE 1D
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
著者Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Bhatia, C., Shrestha, L., Salah, E., Smee, C., Colebrook, S., Berridge, G., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Pike, A.C.W., von Delft, F., Knapp, S., Sundstrom, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.
登録日2006-12-19
公開日2007-02-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
2JIL
  • Download 2jil
  • View 2jil
Molmil generated image of 2jil
CRYSTAL STRUCTURE OF 2ND PDZ DOMAIN OF GLUTAMATE RECEPTOR INTERACTING PROTEIN-1 (GRIP1)
分子名称:GLUTAMATE RECEPTOR INTERACTING PROTEIN-1, THIOCYANATE ION, 1,2-ETHANEDIOL
著者Tickle, J., Elkins, J., Pike, A.C.W., Cooper, C., Salah, E., Papagrigoriou, E., von Delft, F., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2007-06-28
公開日2007-07-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of 2Nd Pdz Domain of Glutamate Receptor Interacting Protein-1 (Grip1)
To be Published
2O2T
  • Download 2o2t
  • View 2o2t
Molmil generated image of 2o2t
THE CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF MPDZ
分子名称:Multiple PDZ domain protein
著者Papagrigoriou, E., Gileadi, C., Phillips, C., Johansson, C., Salah, E., Savitsky, P., Gorrec, F., Umeano, C., Berridge, G., Pike, A.C.W., Elkins, J., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-11-30
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of the 1st PDZ domain of MPDZ
To be Published
2OZF
  • Download 2ozf
  • View 2ozf
Molmil generated image of 2ozf
THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
分子名称:Ezrin-radixin-moesin-binding phosphoprotein 50
著者Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-26
公開日2007-03-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2PD6
  • Download 2pd6
  • View 2pd6
Molmil generated image of 2pd6
STRUCTURE OF HUMAN HYDROXYSTEROID DEHYDROGENASE TYPE 8, HSD17B8
分子名称:Estradiol 17-beta-dehydrogenase 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Turnbull, A.P., Salah, E., Gileadi, O., Savitsky, P., Guo, K., Bunkoczi, G., Pike, A.C.W., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-03-31
公開日2007-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8
To be Published
2PKT
  • Download 2pkt
  • View 2pkt
Molmil generated image of 2pkt
CRYSTAL STRUCTURE OF THE HUMAN CLP-36 (PDLIM1) BOUND TO THE C-TERMINAL PEPTIDE OF HUMAN ALPHA-ACTININ-1
分子名称:PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ...
著者Uppenberg, J., Gileadi, C., Elkins, J., Bray, J., Burgess-Brown, N., Salah, E., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-04-18
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1.
To be Published