2X0L
| Crystal structure of a neuro-specific splicing variant of human histone lysine demethylase LSD1. | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, HISTONE H3 PEPTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ... | Authors: | Zibetti, C, Adamo, A, Binda, C, Forneris, F, Verpelli, C, Ginelli, E, Mattevi, A, Sala, C, Battaglioli, E. | Deposit date: | 2009-12-15 | Release date: | 2010-03-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Alternative Splicing of the Histone Demethylase Lsd1/Kdm1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System. J.Neurosci., 30, 2010
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1IU2
| The first PDZ domain of PSD-95 | Descriptor: | PSD-95 | Authors: | Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M. | Deposit date: | 2002-02-19 | Release date: | 2003-03-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95 J.MOL.BIOL., 327, 2003
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1IU0
| The first PDZ domain of PSD-95 | Descriptor: | PSD-95 | Authors: | Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M. | Deposit date: | 2002-02-18 | Release date: | 2003-03-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95 J.MOL.BIOL., 327, 2003
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3CVF
| Crystal Structure of the carboxy terminus of Homer3 | Descriptor: | Homer protein homolog 3 | Authors: | Hayashi, M.K, Stearns, M.H, Giannini, V, Xu, R.-M, Sala, C, Hayashi, Y. | Deposit date: | 2008-04-18 | Release date: | 2009-03-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell(Cambridge,Mass.), 137, 2009
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3CVE
| Crystal Structure of the carboxy terminus of Homer1 | Descriptor: | Homer protein homolog 1 | Authors: | Hayashi, M.K, Stearns, M.H, Giannini, V, Xu, R.-M, Sala, C, Hayashi, Y. | Deposit date: | 2008-04-18 | Release date: | 2009-03-31 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell(Cambridge,Mass.), 137, 2009
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4BAY
| Phosphomimetic mutant of LSD1-8a splicing variant in complex with CoREST | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1 | Authors: | Toffolo, E, Paganini, L, Rusconi, F, Tortorici, M, Pilotto, S, Verpelli, C, Tedeschi, G, Maffioli, E, Sala, C, Mattevi, A, Battaglioli, E. | Deposit date: | 2012-09-17 | Release date: | 2013-11-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Phosphorylation of Neuronal Lysine-Specific Demethylase 1Lsd1/Kdm1A Impairs Transcriptional Repression by Regulating Interaction with Corest and Histone Deacetylases Hdac1/2. J.Neurochem., 128, 2014
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2G9W
| Crystal Structure of Rv1846c, a Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis | Descriptor: | CHLORIDE ION, conserved hypothetical protein | Authors: | Saul, F.A, Haouz, A, Fiez-Vandal, C, Shepard, W, Alzari, P.M. | Deposit date: | 2006-03-07 | Release date: | 2007-03-13 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis Mol.Microbiol., 71, 2009
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7S6L
| J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut7 S protein (conformation 3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2021-09-14 | Release date: | 2022-05-11 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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7S6K
| J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2021-09-14 | Release date: | 2022-05-11 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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7S6J
| J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2021-09-14 | Release date: | 2022-05-11 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SBU
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7S6I
| SARS-CoV-2-6P-Mut2 S protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2021-09-14 | Release date: | 2022-05-11 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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5J5R
| M. thermoresistible GuaB2 delta-CBS in complex with inhibitor VCC234718 | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, cyclohexyl{4-[(isoquinolin-5-yl)sulfonyl]piperazin-1-yl}methanone | Authors: | Pacitto, A, Ascher, D.B, Blundell, T.L. | Deposit date: | 2016-04-03 | Release date: | 2016-10-19 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis. ACS Infect Dis, 3, 2017
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4DQU
| Mycobacterium tuberculosis InhA-D148G mutant in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-16 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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4DTI
| Mycobacterium tuberculosis InhA-S94A mutant in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-21 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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4DRE
| Mycobacterium tuberculosis InhA in complex with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Pojer, F, Hartkoorn, R.C, Boy, S, Cole, S.T. | Deposit date: | 2012-02-17 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med, 4, 2012
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2XKX
| Single particle analysis of PSD-95 in negative stain | Descriptor: | DISKS LARGE HOMOLOG 4 | Authors: | Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M. | Deposit date: | 2010-07-15 | Release date: | 2011-07-20 | Last modified: | 2019-11-13 | Method: | ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING | Cite: | Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95 Biochim.Biophys.Acta, 1808, 2011
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