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1B7F
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BU of 1b7f by Molmil
SXL-LETHAL PROTEIN/RNA COMPLEX
Descriptor: PROTEIN (SXL-LETHAL PROTEIN), RNA (5'-R(P*GP*UP*UP*GP*UP*UP*UP*UP*UP*UP*UP*U)-3')
Authors:Handa, N, Nureki, O, Kurimoto, K, Kim, I, Sakamoto, H, Shimura, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-01-23
Release date:1999-05-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.
Nature, 398, 1999
1C7W
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NMR SOLUTION STRUCTURE OF THE CALCIUM-BOUND C-TERMINAL DOMAIN (W81-S161) OF CALCIUM VECTOR PROTEIN FROM AMPHIOXUS
Descriptor: CALCIUM VECTOR PROTEIN
Authors:Theret, I, Baladi, S, Cox, J.A, Sakamoto, H, Craescu, C.T.
Deposit date:2000-03-27
Release date:2000-04-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Sequential calcium binding to the regulatory domain of calcium vector protein reveals functional asymmetry and a novel mode of structural rearrangement.
Biochemistry, 39, 2000
1C7V
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BU of 1c7v by Molmil
NMR SOLUTION STRUCTURE OF THE CALCIUM-BOUND C-TERMINAL DOMAIN (W81-S161) OF CALCIUM VECTOR PROTEIN FROM AMPHIOXUS
Descriptor: CALCIUM VECTOR PROTEIN
Authors:Theret, I, Baladi, S, Cox, J.A, Sakamoto, H, Craescu, C.T.
Deposit date:2000-03-27
Release date:2000-04-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Sequential calcium binding to the regulatory domain of calcium vector protein reveals functional asymmetry and a novel mode of structural rearrangement.
Biochemistry, 39, 2000
1DVE
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BU of 1dve by Molmil
CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME
Descriptor: HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2000-01-20
Release date:2000-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
1IRM
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BU of 1irm by Molmil
Crystal structure of apo heme oxygenase-1
Descriptor: apo heme oxygenase-1
Authors:Sugishima, M, Sakamoto, H, Kakuta, Y, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K.
Deposit date:2001-10-09
Release date:2002-07-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of rat apo-heme oxygenase-1 (HO-1): mechanism of heme binding in HO-1 inferred from structural comparison of the apo and heme complex forms
Biochemistry, 41, 2002
2SXL
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BU of 2sxl by Molmil
SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: SEX-LETHAL PROTEIN
Authors:Inoue, M, Muto, Y, Sakamoto, H, Kigawa, T, Takio, K, Shimura, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-07-16
Release date:1998-07-22
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
J.Mol.Biol., 272, 1997
1IX4
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BU of 1ix4 by Molmil
Crystal Structure of Rat Heme Oxygenase-1 in complex with Heme bound to Carbon Monoxide
Descriptor: CARBON MONOXIDE, HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K.
Deposit date:2002-06-10
Release date:2003-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
1IX3
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BU of 1ix3 by Molmil
Crystal Structure of Rat Heme Oxygenase-1 in complex with Heme bound to Cyanide
Descriptor: CYANIDE ION, HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K.
Deposit date:2002-06-10
Release date:2003-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
1D9A
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BU of 1d9a by Molmil
SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN (RBD2) OF HU ANTIGEN C (HUC)
Descriptor: HU ANTIGEN C
Authors:Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-26
Release date:2000-04-07
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1D8Z
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BU of 1d8z by Molmil
SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN (RBD1) OF HU ANTIGEN C (HUC)
Descriptor: HU ANTIGEN C
Authors:Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-26
Release date:2000-04-07
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C.
Nucleic Acids Res., 28, 2000
1DVG
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BU of 1dvg by Molmil
CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME; SELELENO-METHIONINE DERIVATIVE, MUTATED AT M51T,M93L,M155L,M191L.
Descriptor: HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2000-01-20
Release date:2000-04-12
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
1FNX
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BU of 1fnx by Molmil
SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE AU-RICH ELEMENT
Descriptor: AU-RICH RNA ELEMENT, HU ANTIGEN C
Authors:Inoue, M, Hirao, M, Kasashima, K, Kim, I.-S, Kawai, G, Kigawa, T, Sakamoto, H, Muto, Y, Yokoyama, S.
Deposit date:2000-08-24
Release date:2003-06-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of mouse HuC RNA-binding domains complexed with an AU-Rich element reveals determinants of neuronal differentiation
To be Published, 2000
6LUB
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BU of 6lub by Molmil
Crystal Structure of EGFR(L858R/T790M/C797S) in complex with CH7233163
Descriptor: Epidermal growth factor receptor, N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine
Authors:Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H.
Deposit date:2020-01-27
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation.
Mol.Cancer Ther., 19, 2020
6LUD
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BU of 6lud by Molmil
Crystal Structure of EGFR(L858R/T790M/C797S) in complex with Osimertinib
Descriptor: Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
Authors:Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H.
Deposit date:2020-01-27
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation.
Mol.Cancer Ther., 19, 2020
1J2C
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BU of 1j2c by Molmil
Crystal structure of rat heme oxygenase-1 in complex with biliverdin IXalpha-iron cluster
Descriptor: BILIVERDINE IX ALPHA, FE (III) ION, Heme Oxygenase-1
Authors:Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2002-12-29
Release date:2003-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Rat Heme Oxygenase-1 in Complex with Biliverdin-Iron Chelate: CONFORMATIONAL CHANGE OF THE DISTAL HELIX DURING THE HEME CLEAVAGE REACTION.
J.Biol.Chem., 278, 2003
1J7Q
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BU of 1j7q by Molmil
Solution structure and backbone dynamics of the defunct EF-hand domain of Calcium Vector Protein
Descriptor: Calcium Vector Protein
Authors:Theret, I, Baladi, S, Cox, J.A, Gallay, J, Sakamoto, H, Craescu, C.T.
Deposit date:2001-05-18
Release date:2001-06-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the defunct domain of calcium vector protein.
Biochemistry, 40, 2001
1IVJ
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BU of 1ivj by Molmil
Crystal Structure of Rat Hemeoxygenase-1 in Complex with Heme and Azide.
Descriptor: AZIDE ION, Hemeoxygenase-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K.
Deposit date:2002-03-18
Release date:2002-12-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide. IMPLICATION FOR REGIOSPECIFIC HYDROXYLATION OF HEME AT THE alpha -MESO CARBON
J.Biol.Chem., 277, 2002
1J7R
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BU of 1j7r by Molmil
Solution structure and backbone dynamics of the defunct EF-hand domain of Calcium Vector Protein
Descriptor: Calcium Vector Protein
Authors:Theret, I, Baladi, S, Cox, J.A, Gallay, J, Sakamoto, H, Craescu, C.T.
Deposit date:2001-05-18
Release date:2001-06-06
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the defunct domain of calcium vector protein.
Biochemistry, 40, 2001
1UBB
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BU of 1ubb by Molmil
Crystal structure of rat HO-1 in complex with ferrous heme
Descriptor: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Sakamoto, H, Higashimoto, Y, Noguchi, M, Fukuyama, K.
Deposit date:2003-04-03
Release date:2003-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
1ULX
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BU of 1ulx by Molmil
Partially photolyzed structure of CO-bound heme-heme oxygenase complex
Descriptor: CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2003-09-16
Release date:2004-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
1VGI
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BU of 1vgi by Molmil
Crystal structure of xenon bound rat heme-heme oxygenase-1 complex
Descriptor: FORMIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2004-04-26
Release date:2004-08-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
3AOX
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BU of 3aox by Molmil
X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802
Descriptor: 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, ALK tyrosine kinase receptor
Authors:Nagel, S, Moertl, M, Jestel, A, Fukami, T.A.
Deposit date:2010-10-08
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant
Cancer Cell, 19, 2011
1CKE
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BU of 1cke by Molmil
CMP KINASE FROM ESCHERICHIA COLI FREE ENZYME STRUCTURE
Descriptor: PROTEIN (CYTIDINE MONOPHOSPHATE KINASE), SULFATE ION
Authors:Briozzo, P, Golinelli-Pimpaneau, B.
Deposit date:1998-09-24
Release date:1999-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity.
Structure, 6, 1998
1OLG
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BU of 1olg by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR
Descriptor: TUMOR SUPPRESSOR P53 (OLIGOMERIZATION DOMAIN)
Authors:Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
Deposit date:1994-06-13
Release date:1995-01-26
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Science, 265, 1994
1OLH
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BU of 1olh by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR
Descriptor: TUMOR SUPPRESSOR P53 (OLIGOMERIZATION DOMAIN)
Authors:Clore, G.M, Omichinski, J.G, Gronenborn, A.M.
Deposit date:1994-06-13
Release date:1995-03-31
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Science, 265, 1994

 

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