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2NCD
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BU of 2ncd by Molmil
NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION
Authors:Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J.
Deposit date:1999-06-04
Release date:1999-06-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Direction determination in the minus-end-directed kinesin motor ncd.
Nature, 395, 1998
3F7D
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BU of 3f7d by Molmil
SF-1 LBD bound by phosphatidylcholine
Descriptor: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, nuclear receptor SF-1
Authors:Sablin, E.P, Fletterick, R.J.
Deposit date:2008-11-07
Release date:2008-12-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands.
Mol.Endocrinol., 23, 2009
1PK5
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BU of 1pk5 by Molmil
Crystal structure of the orphan nuclear receptor LRH-1
Descriptor: Orphan nuclear receptor NR5A2
Authors:Sablin, E.P, Krylova, I.N, Fletterick, R.J, Ingraham, H.A.
Deposit date:2003-06-04
Release date:2003-07-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1
Mol.Cell, 11, 2003
3F5C
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BU of 3f5c by Molmil
Structure of Dax-1:LRH-1 complex
Descriptor: Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2
Authors:Fletterick, R.J, Sablin, E.P.
Deposit date:2008-11-03
Release date:2008-12-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1.
Proc.Natl.Acad.Sci.USA, 105, 2008
1BG2
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BU of 1bg2 by Molmil
HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, KINESIN, ...
Authors:Kull, F.J, Sablin, E.P, Lau, R, Fletterick, R.J, Vale, R.D.
Deposit date:1998-06-04
Release date:1998-10-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
Nature, 380, 1996
1YMT
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BU of 1ymt by Molmil
Mouse SF-1 LBD
Descriptor: 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1
Authors:Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
Deposit date:2005-01-21
Release date:2005-03-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Cell(Cambridge,Mass.), 120, 2005
1YOW
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BU of 1yow by Molmil
human Steroidogenic Factor 1 LBD with bound Co-factor Peptide
Descriptor: PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide
Authors:Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W.
Deposit date:2005-01-28
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
Cell(Cambridge,Mass.), 120, 2005
1SDM
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BU of 1sdm by Molmil
Crystal structure of kinesin-like calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kinesin heavy chain-like protein
Authors:Vinogradova, M.V, Reddy, V.S, Reddy, A.S, Sablin, E.P, Fletterick, R.J.
Deposit date:2004-02-13
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of kinesin regulated by Ca(2+)-calmodulin.
J.Biol.Chem., 279, 2004
1YOK
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BU of 1yok by Molmil
crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2
Authors:Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
Deposit date:2005-01-27
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Cell(Cambridge,Mass.), 120, 2005
1I6I
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BU of 1i6i by Molmil
CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION, ...
Authors:Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N.
Deposit date:2001-03-02
Release date:2001-05-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Switch-based mechanism of kinesin motors
Nature, 411, 2001
1I5S
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BU of 1i5s by Molmil
CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION
Authors:Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N.
Deposit date:2001-02-28
Release date:2001-05-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Switch-based mechanism of kinesin motors
Nature, 411, 2001
1IA0
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BU of 1ia0 by Molmil
KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ...
Authors:Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N.
Deposit date:2001-03-22
Release date:2002-03-22
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Switch-based Mechanism of Kinesin Motors
Nature, 411, 2001
1MDU
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BU of 1mdu by Molmil
Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Dawson, J.F, Sablin, E.P, Spudich, J.A, Fletterick, R.J.
Deposit date:2002-08-07
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an F-actin trimer disrupted by gelsolin and implications for the mechanism of severing
J.Biol.Chem., 278, 2003
3TX7
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BU of 3tx7 by Molmil
Crystal structure of LRH-1/beta-catenin complex
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2
Authors:Yumoto, F, Fletterick, R.
Deposit date:2011-09-22
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural basis of coactivation of liver receptor homolog-1 by beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
4QK4
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BU of 4qk4 by Molmil
Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to pip2 at 2.8 a resolution
Descriptor: (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1,2-ETHANEDIOL, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ...
Authors:Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
Deposit date:2014-06-05
Release date:2014-07-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.
Proc.Natl.Acad.Sci.USA, 111, 2014
4QJR
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BU of 4qjr by Molmil
Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to its hormone pip3 at 2.4 a resolution
Descriptor: (2S)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dihexadecanoate, ACETATE ION, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ...
Authors:Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL)
Deposit date:2014-06-04
Release date:2014-07-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.
Proc.Natl.Acad.Sci.USA, 111, 2014

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