Author results

3JYH
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HUMAN DIPEPTIDYL PEPTIDASE DPP7
分子名称:Dipeptidyl-peptidase 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
著者Dobrovetsky, E., Dong, A., Seitova, A., Crombett, L., Paganon, S., Cossar, D., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Hassel, A., Shewchuk, L., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2009-09-21
公開日2009-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Human dipeptidyl peptidase DPP7
To be Published
5WCG
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SET AND MYND DOMAIN CONTAINING PROTEIN 2
分子名称:N-lysine methyltransferase SMYD2, ZINC ION, [3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanone, ...
著者Dong, A., Zeng, H., Walker, J.R., Hutch, A., Seitova, A., Tatlock, J., Kumpf, R., Owen, A., Taylor, A., Casimiro-Garcia, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
登録日2017-06-30
公開日2017-08-02
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The crystal structure of SMYD2 in complex with compound MTF003
to be published
6CBX
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CRYSTAL STRUCTURE OF HUMAN SET AND MYND DOMAIN CONTAINING PROTEIN 2 WITH MTF1497
分子名称:N-lysine methyltransferase SMYD2, ZINC ION, [3-(4-amino-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl)azetidin-1-yl][1-({1-[(1R)-cyclohept-2-en-1-yl]piperidin-4-yl}methyl)-1H-pyrrol-3-yl]methanone, ...
著者ZENG, H., DONG, A., Hutchinson, A., Seitova, A., TATLOCK, J., KUMPF, R., OWEN, A., TAYLOR, A., Casimiro-Garcia, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., WU, H., Structural Genomics Consortium (SGC)
登録日2018-02-05
公開日2018-03-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of human SET and MYND Domain Containing protein 2 with MTF1497
to be published
6CBY
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CRYSTAL STRUCTURE OF HUMAN SET AND MYND DOMAIN CONTAINING PROTEIN 2 WITH MTF9975
分子名称:N-lysine methyltransferase SMYD2, ZINC ION, [3-(4-amino-6-methyl-1H-imidazo[4,5-c]pyridin-1-yl)-3-methylazetidin-1-yl][1-({1-[(1R)-cyclohept-2-en-1-yl]piperidin-4-yl}methyl)-1H-pyrrol-3-yl]methanone
著者ZENG, H., DONG, A., Hutchinson, A., Seitova, A., TATLOCK, J., KUMPF, R., OWEN, A., TAYLOR, A., Casimiro-Garcia, A., Bountra, C., Arrowsmith, C.H., Edwards, A.M., BROWN, P.J., WU, H., Structural Genomics Consortium (SGC)
登録日2018-02-05
公開日2018-03-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of human SET and MYND Domain Containing protein 2 with MTF9975
to be published
2ITL
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THE ORIGIN BINDING DOMAIN OF THE SV40 LARGE T ANTIGEN BOUND TO THE FUNCTIONAL PEN PALINDROME DNA (23 BP)
分子名称:24-nt PEN element of the SV40 DNA origin, large T antigen
著者Bochkareva, E., Seitova, A., Bochkarev, A.
登録日2006-10-19
公開日2006-12-12
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
2OXE
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STRUCTURE OF THE HUMAN PANCREATIC LIPASE-RELATED PROTEIN 2
分子名称:Pancreatic lipase-related protein 2, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Walker, J.R., Davis, T., Seitova, A., Finerty Jr., P.J., Butler-Cole, C., Kozieradzki, I., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2007-02-20
公開日2007-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
2PPL
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HUMAN PANCREATIC LIPASE-RELATED PROTEIN 1
分子名称:Pancreatic lipase-related protein 1, CALCIUM ION, SODIUM ION
著者Walker, J.R., Davis, T., Seitova, A., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2007-04-30
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Human Pancreatic Lipase-related Protein 1.
To be Published
3DLJ
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CRYSTAL STRUCTURE OF HUMAN CARNOSINE DIPEPTIDASE 1
分子名称:Beta-Ala-His dipeptidase, ZINC ION, UNKNOWN ATOM OR ION, ...
著者Dong, A., Dobrovetsky, E., Seitova, A., He, H., Tempel, W., Kozieradzki, I., Arrowsmith, C.H., Weigelt, J., Bountra, C., Edwards, A.M., Bochkarev, A., Cossar, D., Structural Genomics Consortium (SGC)
登録日2008-06-27
公開日2008-08-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal structure of human carnosine dipeptidase 1.
To be Published
3GRO
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HUMAN PALMITOYL-PROTEIN THIOESTERASE 1
分子名称:Palmitoyl-protein thioesterase 1, UNKNOWN ATOM OR ION
著者Dobrovetsky, E., Seitova, A., Tong, Y., Tempel, W., Dong, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Cossar, D., Park, H., Structural Genomics Consortium (SGC)
登録日2009-03-26
公開日2009-04-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Human palmitoyl-protein thioesterase 1
To be Published
3ICU
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PROTEASE-ASSOCIATED DOMAIN OF THE E3 LIGASE GRAIL
分子名称:E3 ubiquitin-protein ligase RNF128, N-ACETYL-D-GLUCOSAMINE
著者Walker, J.R., Yermekbayeva, L., Seitova, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2009-07-18
公開日2009-09-29
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献PA Domain of the E3 Ligase Grail
To be Published
3KS9
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METABOTROPIC GLUTAMATE RECEPTOR MGLUR1 COMPLEXED WITH LY341495 ANTAGONIST
分子名称:Metabotropic glutamate receptor 1, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, MAGNESIUM ION, ...
著者Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Cossar, D., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2009-11-20
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metabotropic glutamate receptor mglur1 complexed with LY341495 antagonist
To be Published
3LMK
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LIGAND BINDING DOMAIN OF METABOTROPOC GLUTAMATE RECEPTOR MGLUR5 COMPLEXED WITH GLUTAMATE
分子名称:Metabotropic glutamate receptor 5, N-ACETYL-D-GLUCOSAMINE, GLUTAMIC ACID, ...
著者Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Cossar, D., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2010-01-30
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Metabotropic Glutamate receptor mGluR5 complexed with glutamate
To be Published
3MQ4
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METABOTROPIC GLUTAMATE RECEPTOR MGLUR7 COMPLEXED WITH LY341495 ANTAGONIST
分子名称:Metabotropic glutamate receptor 7, MAGNESIUM ION, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine
著者Dobrovetsky, E., Khutoreskaya, G., Seitova, A., He, H., Weigelt, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Cossar, D., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2010-04-27
公開日2010-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献mGluR7 complexed with LY341495
To be Published
3N0T
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HUMAN DIPEPTIDIL PEPTIDASE DPP7 COMPLEXED WITH INHIBITOR GSK237826A
分子名称:Dipeptidyl peptidase 2, (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
著者Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Crombet, L., Cossar, D., Pagannon, S., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hassell, A., Shewchuk, L., Haffner, C., Bochkarev, A., Structural Genomics Consortium (SGC)
登録日2010-05-14
公開日2010-07-21
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Human dipeptidyl peptidase DPP7
To be Published
3NRU
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LIGAND BINDING DOMAIN OF EPHA7
分子名称:Ephrin receptor, SULFATE ION, CHLORIDE ION
著者Walker, J.R., Yermekbayeva, L., Seitova, A., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.
登録日2010-06-30
公開日2010-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ephrin A7 ligand binding domain
To be Published
3P1I
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LIGAND BINDING DOMAIN OF HUMAN EPHRIN TYPE-B RECEPTOR 3
分子名称:Ephrin type-B receptor 3, SULFATE ION, CHLORIDE ION
著者Walker, J.R., Yermekbayeva, L., Seitova, A., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
登録日2010-09-30
公開日2011-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ligand Binding Domain of Human Ephb3
To be Published
3SM9
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CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR 3 PRECURSOR IN PRESENCE OF LY341495 ANTAGONIST
分子名称:Metabotropic glutamate receptor 3, SULFATE ION, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, ...
著者Wernimont, A.K., Dong, A., Seitova, A., Crombet, L., Khutoreskaya, G., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Cossar, D., Dobrovetsky, E., Structural Genomics Consortium (SGC)
登録日2011-06-27
公開日2011-07-27
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist
TO BE PUBLISHED
4QOX
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CRYSTAL STRUCTURE OF CDPK4 FROM PLASMODIUM FALCIPARUM, PF3D7_0717500
分子名称:Calcium-dependent protein kinase 4, MAGNESIUM ION, 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
著者Wernimont, A.K., Walker, J.R., Hutchinson, A., Seitova, A., He, H., Loppnau, P., Neculai, M., Amani, M., Lin, Y.H., Ravichandran, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Lovato, D.V., Structural Genomics Consortium (SGC)
登録日2014-06-20
公開日2014-09-03
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.748 Å)
主引用文献Crystal Structure of CDPK4 from Plasmodium Falciparum, PF3D7_0717500
TO BE PUBLISHED
4RGJ
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APO CRYSTAL STRUCTURE OF CDPK4 FROM PLASMODIUM FALCIPARUM, PF3D7_0717500
分子名称:Calcium-dependent protein kinase 4
著者Wernimont, A.K., Walker, J.R., Hutchinson, A., Seitova, A., He, H., Loppnau, P., Neculai, M., Amani, M., Lin, Y.H., Ravichandran, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Lovato, D.V., Structural Genomics Consortium (SGC)
登録日2014-09-30
公開日2014-10-29
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Apo crystal structure of CDPK4 from Plasmodium falciparum, PF3D7_0717500
To be Published
4RZ0
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM PUTATIVE HISTONE METHYLTRANSFERASE PFL0690C
分子名称:PFL0690c, UNKNOWN ATOM OR ION
著者Jiang, D.Q., Tempel, W., Loppnau, P., Graslund, S., He, H., Ravichandran, M., Seitova, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., Lin, Y.H., Structural Genomics Consortium (SGC)
登録日2014-12-17
公開日2015-01-21
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.487 Å)
主引用文献Crystal Structure of Plasmodium falciparum putative histone methyltransferase PFL0690c
To be Published
4RZ7
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CRYSTAL STRUCTURE OF PVX_084705 WITH BOUND PCI32765
分子名称:cGMP-dependent protein kinase, putative, 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, ...
著者Jiang, D.Q., Tempel, W., Loppnau, P., Graslund, S., He, H., Seitova, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Amani, M., Structural Genomics Consortium (SGC)
登録日2014-12-18
公開日2015-01-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Crystal Structure of PVX_084705 with bound PCI32765
To be Published
4YY8
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CRYSTAL STRUCTURE ANALYSIS OF KELCH PROTEIN FROM PLASMODIUM FALCIPARUM
分子名称:Kelch protein, UNKNOWN ATOM OR ION, GLYCEROL
著者Jiang, D.Q., Tempel, W., Loppnau, P., Graslund, S., He, H., Ravichandran, M., Seitova, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., El Bakkouri, M., Senisterra, G., Osman, K.T., Lovato, D.V., Hui, R., Hutchinson, A., Lin, Y.H., Structural Genomics Consortium (SGC)
登録日2015-03-23
公開日2015-04-01
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal Structure Analysis of Kelch protein from Plasmodium falciparum.
to be published
4ZGC
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CRYSTAL STRUCTURE ANALYSIS OF KELCH PROTEIN (WITH DISULFIDE BOND) FROM PLASMODIUM FALCIPARUM
分子名称:Kelch protein, UNKNOWN ATOM OR ION
著者Jiang, D.Q., Tempel, W., Loppnau, P., Graslund, S., He, H., Ravichandran, M., Seitova, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., El Bakkouri, M., Senisterra, G., Osman, K.T., Lovato, D.V., Hui, R., Hutchinson, A., Lin, Y.H., Structural Genomics Consortium (SGC)
登録日2015-04-22
公開日2015-06-10
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of kelch protein with disulfide bond from Plasmodium falciparum.
to be published
5DYK
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CRYSTAL STRUCTURE OF PF3D7_1436600
分子名称:CGMP-dependent protein kinase, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of PF3D7_1436600
To Be Published
5DYL
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CRYSTAL STRUCTURE OF PVX_084705
分子名称:cGMP-dependent protein kinase, putative
著者Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
登録日2015-09-24
公開日2015-11-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of PVX_084705
To Be Published
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