4BVM
 
 | | The peripheral membrane protein P2 from human myelin at atomic resolution | | Descriptor: | CITRIC ACID, MYELIN P2 PROTEIN, PALMITIC ACID, ... | | Authors: | Ruskamo, S, Yadav, R.P, Kursula, P. | | Deposit date: | 2013-06-26 | | Release date: | 2014-01-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (0.93 Å) | | Cite: | Atomic Resolution View Into the Structure-Function Relationships of the Human Myelin Peripheral Membrane Protein P2
Acta Crystallogr.,Sect.D, 70, 2014
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6STS
 | | Human myelin protein P2 mutant R30Q | | Descriptor: | Myelin P2 protein, PALMITIC ACID, SULFATE ION | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2019-09-11 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XU5
 | | Human myelin protein P2 mutant N2D | | Descriptor: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-17 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XUA
 | | Human myelin protein P2 mutant K21Q | | Descriptor: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-17 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XW9
 | | Human myelin protein P2 mutant K120S | | Descriptor: | CHLORIDE ION, Myelin P2 protein, PALMITIC ACID | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-23 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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2WFN
 | | Filamin A actin binding domain | | Descriptor: | FILAMIN-A, SULFATE ION | | Authors: | Ruskamo, S, Ylanne, J. | | Deposit date: | 2009-04-09 | | Release date: | 2009-10-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of the Human Filamin a Actin-Binding Domain
Acta Crystallogr.,Sect.D, 65, 2009
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5N4Q
 | | Human myelin protein P2, mutant T51P | | Descriptor: | D-MALATE, Myelin P2 protein, PALMITIC ACID, ... | | Authors: | Ruskamo, S, Kursula, P. | | Deposit date: | 2017-02-11 | | Release date: | 2017-08-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.
Sci Rep, 7, 2017
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5N4M
 | | Human myelin protein P2, mutant I43N | | Descriptor: | D-MALATE, Myelin P2 protein, PALMITIC ACID, ... | | Authors: | Ruskamo, S, Kursula, P. | | Deposit date: | 2017-02-11 | | Release date: | 2017-08-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.
Sci Rep, 7, 2017
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5N4P
 | | Human myelin P2, mutant I52T | | Descriptor: | D-MALATE, Myelin P2 protein, PALMITIC ACID, ... | | Authors: | Ruskamo, S, Kursula, P. | | Deposit date: | 2017-02-11 | | Release date: | 2017-08-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.533 Å) | | Cite: | Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.
Sci Rep, 7, 2017
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6XVS
 | | Human myelin protein P2 mutant P38G, unliganded | | Descriptor: | GLYCEROL, Myelin P2 protein | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-22 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XUW
 | | Human myelin protein P2 mutant L27D | | Descriptor: | CHLORIDE ION, Myelin P2 protein, PALMITIC ACID | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-21 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XVQ
 | | Human myelin protein P2 mutant K31Q | | Descriptor: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-22 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XVY
 | | Human myelin protein P2 mutant R88Q | | Descriptor: | CHLORIDE ION, CITRIC ACID, Myelin P2 protein, ... | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-22 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XU9
 | | Human myelin protein P2 mutant K3N | | Descriptor: | CHLORIDE ION, CITRIC ACID, Myelin P2 protein, ... | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-17 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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6XVR
 | | Human myelin protein P2 mutant L35S | | Descriptor: | Myelin P2 protein, PALMITIC ACID, SULFATE ION | | Authors: | Ruskamo, S, Lehtimaki, M, Kursula, P. | | Deposit date: | 2020-01-22 | | Release date: | 2020-04-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice.
J.Biol.Chem., 295, 2020
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2W0P
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7NRW
 | | Human myelin protein P2 mutant M114T | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Myelin P2 protein, ... | | Authors: | Uusitalo, M, Ruskamo, S, Kursula, P. | | Deposit date: | 2021-03-04 | | Release date: | 2021-09-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.
Febs J., 288, 2021
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7NSR
 | | Myelin protein P2 I50del | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Myelin P2 protein, ... | | Authors: | Uusitalo, M, Ruskamo, S, Kursula, P. | | Deposit date: | 2021-03-08 | | Release date: | 2021-09-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.
Febs J., 288, 2021
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7NTP
 | | Human myelin P2 mutant V115A | | Descriptor: | Myelin P2 protein, PALMITIC ACID | | Authors: | Uusitalo, M, Ruskamo, S, Kursula, P. | | Deposit date: | 2021-03-10 | | Release date: | 2021-09-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.
Febs J., 288, 2021
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4A8Z
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6EXJ
 | | PDZ domain from rat Shank3 bound to the C terminus of somatostatin receptor subtype 2 | | Descriptor: | SH3 and multiple ankyrin repeat domains protein 3, SSTR2 | | Authors: | Ponna, S.K, Keller, C, Ruskamo, S, Myllykoski, M, Boeckers, T.M, Kursula, P. | | Deposit date: | 2017-11-08 | | Release date: | 2018-03-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.
J. Neurochem., 145, 2018
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6ZMM
 | | Crystal structure of human NDRG1 | | Descriptor: | CHLORIDE ION, Protein NDRG1 | | Authors: | Mustonen, V, Kursula, P, Ruskamo, S. | | Deposit date: | 2020-07-03 | | Release date: | 2020-12-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression.
Febs J., 288, 2021
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7B2G
 | | Crystal structure of R120Q GDAP1 mutant | | Descriptor: | GLYCEROL, Ganglioside-induced differentiation-associated protein 1 | | Authors: | Nguyen, G.T.T, Sutinen, A, Kursula, P. | | Deposit date: | 2020-11-26 | | Release date: | 2021-12-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability.
Plos One, 18, 2023
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7O60
 | | Crystal structure of human myelin protein P2 at room temperature from joint X-ray and neutron refinement. | | Descriptor: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | | Authors: | Laulumaa, S, Blakeley, M.P, Kursula, P. | | Deposit date: | 2021-04-09 | | Release date: | 2021-09-01 | | Last modified: | 2021-12-15 | | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | | Cite: | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants.
Febs J., 288, 2021
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2K7Q
 | | Filamin A Ig-like domains 18-19 | | Descriptor: | Filamin-A | | Authors: | Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J. | | Deposit date: | 2008-08-19 | | Release date: | 2009-07-07 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
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