Author results

4Z9K
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH2)(F5)
Descriptor:Ricin, VHH2(F5) antibody, 1,2-ETHANEDIOL, ...
Authors:Rudolph, M.J.
Deposit date:2015-04-10
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
5E1H
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RICIN TOXIN IN COMPLEX WITH NEUTRALIZING SINGLE CHAIN MONOCLONAL ANTIBODIES (VHHS)
Descriptor:Ricin, F8(JOB10) VHH antibody, CHLORIDE ION
Authors:Rudolph, M.J., Vance, D., Shoemaker, C., Mantis, N.
Deposit date:2015-09-29
Release date:2016-08-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins, 84, 2016
1FM0
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MOLYBDOPTERIN SYNTHASE (MOAD/MOAE)
Descriptor:MOLYBDOPTERIN CONVERTING FACTOR, SUBUNIT 1, SUBUNIT 2, ...
Authors:Rudolph, M.J., Wuebbens, M.M., Rajagolpalan, K.V., Schindelin, H.
Deposit date:2000-08-15
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation.
Nat.Struct.Biol., 8, 2001
1FMA
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MOLYBDOPTERIN SYNTHASE (MOAD/MOAE)
Descriptor:MOLYBDOPTERIN CONVERTING FACTOR, SUBUNIT 1, SUBUNIT 2, ...
Authors:Rudolph, M.J., Wuebbens, M.M., Rajagolpalan, K.V., Schindelin, H.
Deposit date:2000-08-16
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation.
Nat.Struct.Biol., 8, 2001
1MJ4
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CRYSTAL STRUCTURE ANALYSIS OF THE CYTOCHROME B5 DOMAIN OF HUMAN SULFITE OXIDASE
Descriptor:sulfite oxidase, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Rudolph, M.J., Johnson, J.L., Rajagopalan, K.V., Kisker, C.
Deposit date:2002-08-26
Release date:2002-09-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The 1.2 A structure of the human sulfite oxidase cytochrome b(5) domain.
Acta Crystallogr.,Sect.D, 59, 2003
1NVI
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ORTHORHOMBIC CRYSTAL FORM OF MOLYBDOPTERIN SYNTHASE
Descriptor:Molybdopterin converting factor subunit 1, Molybdopterin converting factor subunit 2, SULFATE ION, ...
Authors:Rudolph, M.J., Wuebbens, M.M., Turque, O., Rajagopalan, K.V., Schindelin, H.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Molybdopterin Synthase Provide Insights into its Catalytic Mechanism
J.Biol.Chem., 278, 2003
1NVJ
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DELETION MUTANT (DELTA 141) OF MOLYBDOPTERIN SYNTHASE
Descriptor:Molybdopterin converting factor subunit 2, GLYCEROL, FORMIC ACID, ...
Authors:Rudolph, M.J., Wuebbens, M.M., Turque, O., Rajagopalan, K.V., Schindelin, H.
Deposit date:2003-02-03
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Studies of Molybdopterin Synthase Provide Insights into its Catalytic Mechanism
J.Biol.Chem., 278, 2003
2NYC
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CRYSTAL STRUCTURE OF THE BATEMAN2 DOMAIN OF YEAST SNF4
Descriptor:Nuclear protein SNF4
Authors:Rudolph, M.J., Amodeo, G.A., Iram, S., Hong, S., Pirino, G., Carlson, M., Tong, L.
Deposit date:2006-11-20
Release date:2006-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
2NYE
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CRYSTAL STRUCTURE OF THE BATEMAN2 DOMAIN OF YEAST SNF4
Descriptor:Nuclear protein SNF4
Authors:Rudolph, M.J., Amodeo, G.A., Iram, S., Hong, S., Pirino, G., Carlson, M., Tong, L.
Deposit date:2006-11-20
Release date:2006-12-12
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
Structure, 15, 2007
3HYH
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CRYSTAL STRUCTURE OF THE PROTEIN KINASE DOMAIN OF YEAST AMP-ACTIVATED PROTEIN KINASE SNF1
Descriptor:Carbon catabolite-derepressing protein kinase
Authors:Rudolph, M.J., Amodeo, G.A., Bai, Y., Tong, L.
Deposit date:2009-06-22
Release date:2009-06-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1
Biochem.Biophys.Res.Commun., 337, 2005
3MN3
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AN INHIBITED CONFORMATION FOR THE PROTEIN KINASE DOMAIN OF THE SACCHAROMYCES CEREVISIAE AMPK HOMOLOG SNF1
Descriptor:Carbon catabolite-derepressing protein kinase
Authors:Rudolph, M.J., Amodeo, G.A., Tong, L.
Deposit date:2010-04-20
Release date:2010-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1.
Acta Crystallogr.,Sect.F, 66, 2010
4LGP
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH1)
Descriptor:Ricin, VHH1 camelid nanobody, CHLORIDE ION, ...
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LGR
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH3)
Descriptor:Ricin, Camelid nanobody (VHH3), ZINC ION, ...
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LGS
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH4)
Descriptor:Ricin, Camelid nanobody (VHH4)
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-06-28
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LHJ
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH5)
Descriptor:Ricin, Camelid antibody, CHLORIDE ION
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-07-01
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
4LHQ
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH8)
Descriptor:Ricin, Camelid nanobody
Authors:Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N.
Deposit date:2013-07-01
Release date:2014-06-11
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies.
J.Mol.Biol., 426, 2014
5BOZ
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RICIN A CHAIN BOUND TO CAMELID NANOBODY (VHH9)(E1)
Descriptor:Ricin, VHH single chain antibody E1, SULFATE ION, ...
Authors:Rudolph, M.J., Mantis, N.
Deposit date:2015-05-27
Release date:2016-12-07
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
5J56
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RTA-V1C7
Descriptor:Ricin, VHH single chain antibody V1C7, TETRAETHYLENE GLYCOL, ...
Authors:Rudolph, M.J.
Deposit date:2016-04-01
Release date:2016-12-07
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
5J57
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V5E1-RTA COMPLEX
Descriptor:Ricin, VHH single chain antibody V5E1, CHLORIDE ION, ...
Authors:Rudolph, M.J.
Deposit date:2016-04-01
Release date:2016-12-07
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.
J. Biol. Chem., 292, 2017
6CWG
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RICIN CATALYTIC SUBUNIT BOUND GO A9 VHH ANTIBODY
Descriptor:Ricin, VHH antibody, CHLORIDE ION
Authors:Rudolph, M.J., Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
6CWK
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ANTI-RTA VHH ANTIBODY
Descriptor:Anti-Ricin antibody, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Rudolph, M.J., Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Method:X-RAY DIFFRACTION (1.256 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
4NBQ
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STRUCTURE OF THE POLYNUCLEOTIDE PHOSPHORYLASE (CBU_0852) FROM COXIELLA BURNETII
Descriptor:Polyribonucleotide nucleotidyltransferase, SULFATE ION
Authors:Rudolph, M.J., Cheung, J., Franklin, M.C., Cassidy, M., Gary, E., Burshteyn, F., Love, J.
Deposit date:2013-10-23
Release date:2015-06-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.9138 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
5U4L
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RTA-V1C7_G29R-HIGH-SALT
Descriptor:Ricin, V1C7 VHH antibody G29R variant, PHOSPHATE ION, ...
Authors:Rudolph, M.J., Mantis, N.
Deposit date:2016-12-05
Release date:2017-12-13
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.
Proteins, 85, 2017
5U4M
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RTA-V1C7-G29R-NO_SALT
Descriptor:Ricin, V1C7 VHH antibody, CHLORIDE ION
Authors:Rudolph, M.J., Mantis, N.
Deposit date:2016-12-05
Release date:2017-12-13
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.
Proteins, 85, 2017
1MJ3
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CRYSTAL STRUCTURE ANALYSIS OF RAT ENOYL-COA HYDRATASE IN COMPLEX WITH HEXADIENOYL-COA
Descriptor:ENOYL-COA HYDRATASE, MITOCHONDRIAL, HEXANOYL-COENZYME A
Authors:Bell, A.F., Feng, Y., Hofstein, H.A., Parikh, S., Wu, J., Rudolph, M.J., Kisker, C., Tonge, P.J.
Deposit date:2002-08-26
Release date:2002-09-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stereoselectivity of Enoyl-CoA Hydratase Results from Preferential Activation of One of Two Bound Substrate Conformers
Chem.Biol., 9, 2002