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6CB8
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BU of 6cb8 by Molmil
Cryo-EM structure of the Gasdermin A3 membrane pore
Descriptor: CARDIOLIPIN, Gasdermin-A3
Authors:Ruan, J, Wu, H.
Deposit date:2018-02-02
Release date:2018-04-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the gasdermin A3 membrane pore.
Nature, 557, 2018
4DQN
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BU of 4dqn by Molmil
Crystal structure of the branched-chain aminotransferase from Streptococcus mutans
Descriptor: Putative branched-chain amino acid aminotransferase IlvE
Authors:Ruan, J, Li, S.T.
Deposit date:2012-02-16
Release date:2013-01-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of the branched-chain aminotransferase from Streptococcus mutans
Acta Crystallogr.,Sect.D, 68, 2012
3OTR
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BU of 3otr by Molmil
2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii
Descriptor: CHLORIDE ION, Enolase, SULFATE ION
Authors:Minasov, G, Ruan, J, Shuvalova, L, Halavaty, A, Ngo, H, Tomavo, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-13
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions.
Acta Crystallogr.,Sect.D, 71, 2015
8EFP
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BU of 8efp by Molmil
CryoEM structure of GSDMB in complex with shigella IpaH7.8
Descriptor: Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Wang, C, Ruan, J.
Deposit date:2022-09-08
Release date:2023-03-29
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for GSDMB pore formation and its targeting by IpaH7.8.
Nature, 616, 2023
8ET1
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BU of 8et1 by Molmil
CryoEM structure of GSDMB pore without transmembrane beta-barrel
Descriptor: Isoform 1 of Gasdermin-B
Authors:Wang, C, Ruan, J.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4.48 Å)
Cite:Structural basis for GSDMB pore formation and its targeting by IpaH7.8.
Nature, 616, 2023
8ET2
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BU of 8et2 by Molmil
CryoEM structure of the GSDMB pore
Descriptor: Isoform 1 of Gasdermin-B
Authors:Wang, C, Ruan, J.
Deposit date:2022-10-15
Release date:2023-03-29
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4.96 Å)
Cite:Structural basis for GSDMB pore formation and its targeting by IpaH7.8.
Nature, 616, 2023
5BXI
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BU of 5bxi by Molmil
1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site
Descriptor: BICARBONATE ION, DI(HYDROXYETHYL)ETHER, Nucleoside diphosphate kinase
Authors:Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-06-09
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
3JBL
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BU of 3jbl by Molmil
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
Descriptor: NLR family CARD domain-containing protein 4
Authors:Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H.
Deposit date:2015-09-05
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
3J63
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BU of 3j63 by Molmil
Unified assembly mechanism of ASC-dependent inflammasomes
Descriptor: Apoptosis-associated speck-like protein containing a CARD
Authors:Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H.
Deposit date:2013-12-05
Release date:2014-03-26
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.
Cell(Cambridge,Mass.), 156, 2014
6VFE
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BU of 6vfe by Molmil
Gasdermin D pore
Descriptor: Gasdermin-D, N-terminal
Authors:Xia, S, Ruan, J, Wu, H.
Deposit date:2020-01-03
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Nature, 593, 2021
3T41
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BU of 3t41 by Molmil
1.95 Angstrom Resolution Crystal Structure of Epidermin Leader Peptide Processing Serine Protease (EpiP) S393A Mutant from Staphylococcus aureus
Descriptor: CALCIUM ION, CHLORIDE ION, Epidermin leader peptide processing serine protease EpiP
Authors:Minasov, G, Kuhn, M, Ruan, J, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-25
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:1.95 Angstrom Resolution Crystal Structure of Epidermin Leader Peptide Processing Serine Protease (EpiP) S393A Mutant from Staphylococcus aureus.
TO BE PUBLISHED
3MP1
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BU of 3mp1 by Molmil
Complex structure of Sgf29 and trimethylated H3K4
Descriptor: ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ...
Authors:Li, J, Ruan, J, Wu, M, Xue, X, Zang, J.
Deposit date:2010-04-24
Release date:2011-05-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP8
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BU of 3mp8 by Molmil
Crystal structure of Sgf29 tudor domain
Descriptor: 4-(HYDROXYMETHYL)BENZAMIDINE, ACETIC ACID, GLYCEROL, ...
Authors:Li, J, Wu, M, Ruan, J, Zang, J.
Deposit date:2010-04-26
Release date:2011-05-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP6
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BU of 3mp6 by Molmil
Complex Structure of Sgf29 and dimethylated H3K4
Descriptor: H3K4me2 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Li, J, Wu, M, Ruan, J, Zang, J.
Deposit date:2010-04-25
Release date:2011-05-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3R93
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BU of 3r93 by Molmil
Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
Descriptor: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION
Authors:Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC)
Deposit date:2011-03-24
Release date:2011-04-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3LWE
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BU of 3lwe by Molmil
The crystal structure of MPP8
Descriptor: M-phase phosphoprotein 8
Authors:Li, Z, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC)
Deposit date:2010-02-23
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3SB1
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BU of 3sb1 by Molmil
Hydrogenase expression protein HupH from Thiobacillus denitrificans ATCC 25259
Descriptor: GLYCEROL, TRIETHYLENE GLYCOL, hydrogenase expression protein
Authors:Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Ruan, J, Leo, R.D, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2011-06-03
Release date:2011-07-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Hydrogenase expression protein HupH from Thiobacillus denitrificans ATCC 25259
To be Published
4EIV
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BU of 4eiv by Molmil
1.37 Angstrom resolution crystal structure of apo-form of a putative deoxyribose-phosphate aldolase from Toxoplasma gondii ME49
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Deoxyribose-phosphate aldolase
Authors:Halavaty, A.S, Ruan, J, Minasov, G, Shuvalova, L, Ueno, A, Igarashi, M, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-04-05
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural and Functional Divergence of the Aldolase Fold in Toxoplasma gondii.
J.Mol.Biol., 427, 2015
4FBD
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BU of 4fbd by Molmil
2.35 Angstrom Crystal Structure of Conserved Hypothetical Protein from Toxoplasma gondii ME49.
Descriptor: Putative uncharacterized protein
Authors:Minasov, G, Ruan, J, Wawrzak, Z, Shuvalova, L, Ngo, H, Knoll, L, Milligan-Myhre, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-05-22
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom Crystal Structure of Conserved Hypothetical Protein from Toxoplasma gondii ME49.
TO BE PUBLISHED
4D2J
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BU of 4d2j by Molmil
Crystal structure of F16BP Aldolase from Toxoplasma gondii (TgALD1)
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, FRUCTOSE-BISPHOSPHATE ALDOLASE, ...
Authors:Tonkin, M.L, Ramaswamy, R, Halavaty, A.S, Ruan, J, Igarashi, M, Ngo, H.M, Boulanger, M.J.
Deposit date:2014-05-09
Release date:2014-10-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Functional Divergence of the Aldolase Fold in Toxoplasma Gondii.
J.Mol.Biol., 427, 2015
4IR8
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BU of 4ir8 by Molmil
1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Sedoheptulose-1,7 bisphosphatase, ...
Authors:Minasov, G, Ruan, J, Wawrzak, Z, Halavaty, A, Shuvalova, L, Harb, O.S, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-01-14
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii.
TO BE PUBLISHED
4MJZ
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BU of 4mjz by Molmil
2.75 Angstrom Resolution Crystal Structure of Putative Orotidine-monophosphate-decarboxylase from Toxoplasma gondii.
Descriptor: DI(HYDROXYETHYL)ETHER, NITRATE ION, Orotidine 5'-phosphate decarboxylase, ...
Authors:Minasov, G, Wawrzak, Z, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-04
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:2.75 Angstrom Resolution Crystal Structure of Putative Orotidine-monophosphate-decarboxylase from Toxoplasma gondii.
TO BE PUBLISHED
4NML
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BU of 4nml by Molmil
2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid
Descriptor: CHLORIDE ION, D-MALATE, Ribulose 5-phosphate isomerase
Authors:Halavaty, A.S, Dubrovska, I, Flores, K, Shanmugam, D, Shuvalova, L, Roos, D, Ruan, J, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-15
Release date:2013-12-04
Last modified:2021-01-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4NOG
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BU of 4nog by Molmil
Crystal structure of a putative ornithine aminotransferase from Toxoplasma gondii ME49 in complex with pyrodoxal-5'-phosphate
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Filippova, E.V, Halavaty, A, Ruan, J, Shuvalova, L, Flores, K, Dubrovska, I, Ngo, H, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-19
Release date:2013-12-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4NU7
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BU of 4nu7 by Molmil
2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
Descriptor: CHLORIDE ION, Ribulose-phosphate 3-epimerase, SULFATE ION, ...
Authors:Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-12-03
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018

 

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