Author results

1AJW
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STRUCTURE OF RHOGDI: A C-TERMINAL BINDING DOMAIN TARGETS AN N-TERMINAL INHIBITORY PEPTIDE TO GTPASES, NMR, 20 STRUCTURES
Descriptor:RHOGDI
Authors:Rosen, M.K., Gosser, Y.Q.
Deposit date:1997-05-11
Release date:1997-11-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature, 387, 1997
1GDF
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STRUCTURE OF RHOGDI: A C-TERMINAL BINDING DOMAIN TARGETS AN N-TERMINAL INHIBITORY PEPTIDE TO GTPASES, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:RHOGDI
Authors:Rosen, M.K., Gosser, Y.Q.
Deposit date:1997-05-11
Release date:1997-11-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature, 387, 1997
3KY9
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AUTOINHIBITED VAV1
Descriptor:Proto-oncogene vav, ZINC ION
Authors:Tomchick, D.R., Rosen, M.K., Machius, M., Yu, B.
Deposit date:2009-12-04
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
1FKR
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SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor:FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W., Rosen, M.K., Wandless, T.J., Karplus, M., Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1FKS
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SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor:FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W., Rosen, M.K., Wandless, T.J., Karplus, M., Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1FKT
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SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor:FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W., Rosen, M.K., Wandless, T.J., Karplus, M., Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1SRL
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1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor:SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H., Rosen, M.K., Shin, T.B., Seidel-Dugan, C., Brugge, J.S., Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
1SRM
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1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor:SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H., Rosen, M.K., Shin, T.B., Seidel-Dugan, C., Brugge, J.S., Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
4M63
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CRYSTAL STRUCTURE OF A FILAMENT-LIKE ACTIN TRIMER BOUND TO THE BACTERIAL EFFECTOR VOPL
Descriptor:T3SS2 effector VopL nucleation of actin polymerization, Actin-5C, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tomchick, D.R., Zahm, J.A., Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
1BY1
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DBL HOMOLOGY DOMAIN FROM BETA-PIX
Descriptor:PROTEIN (PIX)
Authors:Aghazadeh, B., Zhu, K., Kubiseski, T.J., Liu, G.A., Pawson, T., Zheng, Y., Rosen, M.K.
Deposit date:1998-10-22
Release date:1999-10-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Mutagenesis of the Dbl Homology Domain
Nat.Struct.Biol., 5, 1998
1CEE
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SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP
Descriptor:GTP-BINDING RHO-LIKE PROTEIN, WISKOTT-ALDRICH SYNDROME PROTEIN WASP, MAGNESIUM ION, ...
Authors:Abdul-Manan, N., Aghazadeh, B., Liu, G.A., Majumdar, A., Ouerfelli, O., Rosen, M.K.
Deposit date:1999-03-08
Release date:1999-06-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
Nature, 399, 1999
1EJ5
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SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP
Descriptor:WISKOTT-ALDRICH SYNDROME PROTEIN
Authors:Kim, A.S., Kakalis, L.T., Abdul-Manan, N., Liu, G.A., Rosen, M.K.
Deposit date:2000-02-29
Release date:2000-04-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Nature, 404, 2000
1F5X
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NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLOGY DOMAIN
Descriptor:RHO-GEF VAV
Authors:Aghazadeh, B., Rosen, M.K., Lowry, W.E., Huang, X.Y.
Deposit date:2000-06-18
Release date:2000-09-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation.
Cell(Cambridge,Mass.), 102, 2000
1NF3
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STRUCTURE OF CDC42 IN A COMPLEX WITH THE GTPASE-BINDING DOMAIN OF THE CELL POLARITY PROTEIN, PAR6
Descriptor:G25K GTP-binding protein, placental isoform, PAR-6B, ...
Authors:Garrard, S.M., Capaldo, C.T., Gao, L., Rosen, M.K., Macara, I.G., Tomchick, D.R.
Deposit date:2002-12-12
Release date:2003-03-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
1OMA
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SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor:OMEGA-AGA-IVB
Authors:Yu, H., Rosen, M.K., Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993
1OMB
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SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor:OMEGA-AGA-IVB
Authors:Yu, H., Rosen, M.K., Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993
1T84
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SOLUTION STRUCTURE OF THE WISKOTT-ALDRICH SYNDROME PROTEIN (WASP) AUTOINHIBITED CORE DOMAIN COMPLEXED WITH (S)-WISKOSTATIN, A SMALL MOLECULE INHIBITOR
Descriptor:Wiskott-Aldrich syndrome protein, (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
Authors:Peterson, J.R., Bickford, L.C., Morgan, D., Kim, A.S., Ouerfelli, O., Kirschner, M.W., Rosen, M.K.
Deposit date:2004-05-11
Release date:2004-07-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
1Y64
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BNI1P FORMIN HOMOLOGY 2 DOMAIN COMPLEXED WITH ATP-ACTIN
Descriptor:Actin, alpha skeletal muscle, BNI1 protein, ...
Authors:Otomo, T., Tomchick, D.R., Otomo, C., Panchal, S.C., Machius, M., Rosen, M.K.
Deposit date:2004-12-03
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Nature, 433, 2005
1ZZV
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SOLUTION NMR STRUCTURE OF THE PERIPLASMIC SIGNALING DOMAIN OF THE OUTER MEMBRANE IRON TRANSPORTER FECA FROM ESCHERICHIA COLI.
Descriptor:Iron(III) dicitrate transport protein fecA
Authors:Ferguson, A.D., Amezcua, C.A., Chelliah, Y., Rosen, M.K., Deisenhofer, J.
Deposit date:2005-06-14
Release date:2006-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2A02
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SOLUTION NMR STRUCTURE OF THE PERIPLASMIC SIGNALING DOMAIN OF THE OUTER MEMBRANE IRON TRANSPORTER PUPA FROM PSEUDOMONAS PUTIDA.
Descriptor:Ferric-pseudobactin 358 receptor
Authors:Ferguson, A.D., Amezcua, C.A., Chelliah, Y., Rosen, M.K., Deisenhofer, J.
Deposit date:2005-06-15
Release date:2006-09-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2BNX
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CRYSTAL STRUCTURE OF THE DIMERIC REGULATORY DOMAIN OF MOUSE DIAPHANEOUS-RELATED FORMIN (DRF), MDIA1
Descriptor:DIAPHANOUS PROTEIN HOMOLOG 1, CHLORIDE ION
Authors:Otomo, T., Otomo, C., Tomchick, D.R., Machius, M., Rosen, M.K.
Deposit date:2005-04-05
Release date:2005-06-13
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
2K42
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SOLUTION STRUCTURE OF THE GTPASE BINDING DOMAIN OF WASP IN COMPLEX WITH ESPFU, AN EHEC EFFECTOR
Descriptor:Wiskott-Aldrich syndrome protein, ESPFU
Authors:Cheng, H.-C., Skehan, B.M., Campellone, K.G., Leong, J.M., Rosen, M.K.
Deposit date:2008-05-27
Release date:2008-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).
Nature, 454, 2008
3OBV
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AUTOINHIBITED FORMIN MDIA1 STRUCTURE
Descriptor:Protein diaphanous homolog 1, SUCROSE
Authors:Tomchick, D.R., Rosen, M.K., Otomo, T.
Deposit date:2010-08-09
Release date:2010-11-24
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the Formin mDia1 in autoinhibited conformation.
Plos One, 5, 2010
3P8C
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STRUCTURE AND CONTROL OF THE ACTIN REGULATORY WAVE COMPLEX
Descriptor:Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, Wiskott-Aldrich syndrome protein family member 1, ...
Authors:Chen, Z., Borek, D., Padrick, S.B., Gomez, T.S., Metlagel, Z., Ismail, A.M., Umetani, J., Billadeau, D.D., Otwinowski, Z., Rosen, M.K.
Deposit date:2010-10-13
Release date:2010-12-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure and control of the actin regulatory WAVE complex.
Nature, 468, 2010
3SEO
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CRYSTAL STRUCTURE OF VOPL C TERMINAL DOMAIN
Descriptor:VopL C terminal domain protein, CHLORIDE ION
Authors:Yu, B., Rosen, M.K., Tomchick, D.R.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:Mechanism of actin filament nucleation by the bacterial effector VopL.
Nat.Struct.Mol.Biol., 18, 2011
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