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Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody
Descriptor:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ...
Authors:	Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K.
Deposit date:	2018-12-21
Release date:	2019-12-25
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.381 Å)
Cite:	Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Sci Adv, 5, 2019

Crystal structure of human FcRn with a peptide inhibitor at multiple sites
Descriptor:	Beta-2-microglobulin, IgG receptor FcRn large subunit p51, peptide inhibitor
Authors:	Nienaber, V, Badger, J.
Deposit date:	2016-10-23
Release date:	2017-03-22
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db
Descriptor:	Beta-2-microglobulin, H13b peptide, H2-Db major histocompatibility antigen
Authors:	Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D.C, Nathenson, S.G.
Deposit date:	2001-08-24
Release date:	2002-03-20
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination. J.Immunol., 168, 2002