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6GOP
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BU of 6gop by Molmil
Yeast 20S Proteasome in complex with Homosalinosporamide A
Descriptor: CHLORIDE ION, Homosalinosporamide A - bound form, MAGNESIUM ION, ...
Authors:Groll, M, Romo, D.
Deposit date:2018-06-01
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:(-)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study.
Mar Drugs, 16, 2018
5MEI
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BU of 5mei by Molmil
Crystal structure of Agelastatin A bound to the 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O.
Deposit date:2016-11-15
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
6XKI
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BU of 6xki by Molmil
Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog
Descriptor: (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ...
Authors:Liang, J, Naineni, S.K, Pelletier, J, Nagar, B.
Deposit date:2020-06-26
Release date:2021-01-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Cell Chem Biol, 28, 2021
7S2X
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BU of 7s2x by Molmil
Structure of SalC, a gamma-lactam-beta-lactone bicyclase for salinosporamide biosynthesis
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, POTASSIUM ION, SalC
Authors:Chen, P.Y.-T, Trivella, D.B.B, Bauman, K.D, Moore, B.S.
Deposit date:2021-09-04
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Enzymatic assembly of the salinosporamide gamma-lactam-beta-lactone anticancer warhead.
Nat.Chem.Biol., 18, 2022
7S8W
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BU of 7s8w by Molmil
Amycolatopsis sp. T-1-60 N-succinylamino acid racemase/o-succinylbenzoate synthase R266Q mutant in complex with N-succinylphenylglycine
Descriptor: MAGNESIUM ION, N-succinyl-L-phenylglycine, N-succinylamino acid racemase/O-succinylbenzoate synthase, ...
Authors:Truong, D.P, Rousseau, S, Sacchettini, J.C, Glasner, M.E.
Deposit date:2021-09-20
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Second-Shell Amino Acid R266 Helps Determine N -Succinylamino Acid Racemase Reaction Specificity in Promiscuous N -Succinylamino Acid Racemase/ o -Succinylbenzoate Synthase Enzymes.
Biochemistry, 60, 2021

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PDB entries from 2024-03-27

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