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3H42
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BU of 3h42 by Molmil
Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody
Descriptor: Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E.
Deposit date:2009-04-17
Release date:2009-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
2PMW
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BU of 2pmw by Molmil
The Crystal Structure of Proprotein convertase subtilisin kexin type 9 (PCSK9)
Descriptor: Proprotein convertase subtilisin/kexin type 9, SULFATE ION
Authors:Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C.
Deposit date:2007-04-23
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol.
Structure, 15, 2007
4XX1
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BU of 4xx1 by Molmil
Low resolution structure of LCAT in complex with Fab1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1 heavy chain, Fab1 light chain, ...
Authors:Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T.
Deposit date:2015-01-29
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The high-resolution crystal structure of human LCAT.
J.Lipid Res., 56, 2015
4XWG
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BU of 4xwg by Molmil
Crystal Structure of LCAT (C31Y) in complex with Fab1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1 Heavy Chain, Fab1 Light Chain, ...
Authors:Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T.
Deposit date:2015-01-28
Release date:2015-07-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The high-resolution crystal structure of human LCAT.
J.Lipid Res., 56, 2015
5BV7
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BU of 5bv7 by Molmil
Crystal structure of human LCAT (L4F, N5D) in complex with Fab of an agonistic antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 27C3 heavy chain, 27C3 light chain, ...
Authors:Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C.
Deposit date:2015-06-04
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism.
J.Biol.Chem., 291, 2016

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