Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1AN4
DownloadVisualize
BU of 1an4 by Molmil
STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
Descriptor: DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR)
Authors:Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K.
Deposit date:1997-03-15
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and function of the b/HLH/Z domain of USF.
EMBO J., 13, 1994
1CDW
DownloadVisualize
BU of 1cdw by Molmil
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
Descriptor: DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP))
Authors:Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K.
Deposit date:1996-04-11
Release date:1996-12-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a human TATA box-binding protein/TATA element complex.
Proc.Natl.Acad.Sci.USA, 93, 1996
1J2X
DownloadVisualize
BU of 1j2x by Molmil
Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide
Descriptor: RNA polymerase II CTD phosphatase, SULFATE ION, Transcription initiation factor IIF, ...
Authors:Kamada, K, Roeder, R.G, Burley, S.K.
Deposit date:2003-01-15
Release date:2003-01-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF
Proc.Natl.Acad.Sci.USA, 100, 2003
6DRD
DownloadVisualize
BU of 6drd by Molmil
RNA Pol II(G)
Descriptor: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G.
Deposit date:2018-06-11
Release date:2019-06-12
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25, 2018
2H7B
DownloadVisualize
BU of 2h7b by Molmil
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Descriptor: Core-binding factor, ML1-ETO
Authors:Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M.
Deposit date:2006-06-01
Release date:2006-07-11
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
Proc.Natl.Acad.Sci.USA, 103, 2006
1TAF
DownloadVisualize
BU of 1taf by Molmil
DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER
Descriptor: TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION
Authors:Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K.
Deposit date:1996-06-01
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature, 380, 1996
1VOL
DownloadVisualize
BU of 1vol by Molmil
TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX
Descriptor: DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ...
Authors:Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K.
Deposit date:1996-04-29
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Nature, 377, 1995
1I27
DownloadVisualize
BU of 1i27 by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF)
Descriptor: TRANSCRIPTION FACTOR IIF, ZINC ION
Authors:Kamada, K, De Angelis, J, Roeder, R.G, Burley, S.K.
Deposit date:2001-02-07
Release date:2001-03-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JFI
DownloadVisualize
BU of 1jfi by Molmil
Crystal Structure of the NC2-TBP-DNA Ternary Complex
Descriptor: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ...
Authors:Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-06-20
Release date:2001-07-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
6ZLY
DownloadVisualize
BU of 6zly by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand NV1362 (7a)
Descriptor: (2~{S})-2-[(4-hexoxyphenyl)carbonylamino]-3-methyl-butanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2020-07-01
Release date:2020-11-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
8I60
DownloadVisualize
BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
Descriptor: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
Authors:Konuma, T, Zhou, M.-M.
Deposit date:2023-01-26
Release date:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
4JOL
DownloadVisualize
BU of 4jol by Molmil
Complex structure of AML1-ETO NHR2 domain with HEB fragment
Descriptor: Protein CBFA2T1, Transcription factor 12
Authors:Wang, Z, Patel, D.J.
Deposit date:2013-03-18
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature, 500, 2013
7FAX
DownloadVisualize
BU of 7fax by Molmil
Complex structure of TbLeo1 and LW domain from Trypanosoma brucei
Descriptor: TbLW, TbLeo1 peptide
Authors:Liao, S, Gao, J, Tu, X.
Deposit date:2021-07-07
Release date:2022-07-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
7FAW
DownloadVisualize
BU of 7faw by Molmil
Structure of LW domain from Yeast
Descriptor: Transcription elongation factor S-II
Authors:Liao, S, Gao, J, Tu, X.
Deposit date:2021-07-07
Release date:2022-07-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.438 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
6AF0
DownloadVisualize
BU of 6af0 by Molmil
Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila
Descriptor: Cdc73 protein, Ctr9 protein, Paf1 protein
Authors:Wang, Z, Deng, P, Zhou, Y.
Deposit date:2018-08-07
Release date:2018-09-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6O7G
DownloadVisualize
BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
Descriptor: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
Authors:Zhang, Y, Kutateladze, T.G.
Deposit date:2019-03-07
Release date:2019-05-22
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
7XUR
DownloadVisualize
BU of 7xur by Molmil
The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE
Descriptor: DNA (35-MER), ZINC ION, snRNA-activating protein complex subunit 1, ...
Authors:Wang, W, Sun, J.F.
Deposit date:2022-05-19
Release date:2022-12-07
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter.
Nat Commun, 13, 2022
7XGW
DownloadVisualize
BU of 7xgw by Molmil
Apo structure of LW domain from Trypanosoma brucei
Descriptor: Transcription elongation factor s-II
Authors:Liao, S, Gao, J, Chen, M, Tu, X.
Deposit date:2022-04-06
Release date:2023-05-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
6QJ5
DownloadVisualize
BU of 6qj5 by Molmil
X-ray structure of PPARgamma LBD with the ligand NV1380
Descriptor: (2~{S})-3-methyl-2-[(4-octoxyphenyl)carbonylamino]butanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, R, Capelli, D.
Deposit date:2019-01-22
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
5HJB
DownloadVisualize
BU of 5hjb by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K9
Descriptor: Protein AF-9, peptide of Histone H3.1
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-12
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
DownloadVisualize
BU of 5hjd by Molmil
AF9 YEATS in complex with histone H3 Crotonylation at K18
Descriptor: COPPER (II) ION, Protein AF-9, SULFATE ION, ...
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.806 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
5HJC
DownloadVisualize
BU of 5hjc by Molmil
BRD3 second bromodomain in complex with histone H3 acetylation at K18
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ...
Authors:Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
Deposit date:2016-01-13
Release date:2016-04-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
1C9B
DownloadVisualize
BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F, Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1TFB
DownloadVisualize
BU of 1tfb by Molmil
NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES
Descriptor: TFIIB
Authors:Bagby, S, Ikura, M.
Deposit date:1996-11-14
Release date:1997-03-12
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Human general transcription factor TFIIB: conformational variability and interaction with VP16 activation domain.
Biochemistry, 37, 1998
1TBP
DownloadVisualize
BU of 1tbp by Molmil
CRYSTAL STRUCTURE OF YEAST TATA-BINDING PROTEIN AND MODEL FOR INTERACTION WITH DNA
Descriptor: TATA-BINDING PROTEIN
Authors:Chasman, D.I, Flaherty, K.M, Sharp, P.A, Kornberg, R.D.
Deposit date:1993-08-02
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
Proc.Natl.Acad.Sci.USA, 90, 1993

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon