Author results

4W2F
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH AMICOUMACIN, MRNA AND THREE DEACYLATED TRNAS IN THE A, P AND E SITES
Descriptor:16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ...
Authors:Polikanov, Y.S., Osterman, I.A., Szal, T., Tashlitsky, V.N., Serebryakova, M.V., Kusochek, P., Bulkley, D., Malanicheva, I.A., Efimenko, T.A., Efremenkova, O.V., Konevega, A.L., Shaw, K.J., Bogdanov, A.A., Rodnina, M.V., Dontsova, O.A., Mankin, A.S., Steitz, T.A., Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2G
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH PACTAMYCIN (SOAKED), MRNA AND THREE DEACYLATED TRNAS IN THE A, P AND E SITES
Descriptor:16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ...
Authors:Polikanov, Y.S., Osterman, I.A., Szal, T., Tashlitsky, V.N., Serebryakova, M.V., Kusochek, P., Bulkley, D., Malanicheva, I.A., Efimenko, T.A., Efremenkova, O.V., Konevega, A.L., Shaw, K.J., Bogdanov, A.A., Rodnina, M.V., Dontsova, O.A., Mankin, A.S., Steitz, T.A., Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2H
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH PACTAMYCIN (CO-CRYSTALLIZED), MRNA AND DEACYLATED TRNA IN THE P SITE
Descriptor:16S Ribosomal RNA, 30S Ribosomal Protein S2, 30S Ribosomal Protein S3, ...
Authors:Polikanov, Y.S., Osterman, I.A., Szal, T., Tashlitsky, V.N., Serebryakova, M.V., Kusochek, P., Bulkley, D., Malanicheva, I.A., Efimenko, T.A., Efremenkova, O.V., Konevega, A.L., Shaw, K.J., Bogdanov, A.A., Rodnina, M.V., Dontsova, O.A., Mankin, A.S., Steitz, T.A., Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2015-01-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
1MJ1
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FITTING THE TERNARY COMPLEX OF EF-TU/TRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
Descriptor:Phe-tRNA, sarcin-ricin loop of 23SrRNA, helix 69 of 23S rRNA, ...
Authors:Stark, H., Rodnina, M.V., Wieden, H.-J., Zemlin, F., Wintermeyer, W., Vanheel, M.
Deposit date:2002-08-26
Release date:2002-11-01
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
1ZAV
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RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P21
Descriptor:50S ribosomal protein L10, 50S ribosomal protein L7/L12
Authors:Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C.
Deposit date:2005-04-07
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
1ZAW
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RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P212121, FORM A
Descriptor:50S ribosomal protein L10, 50S ribosomal protein L7/L12
Authors:Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C.
Deposit date:2005-04-07
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
1ZAX
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RIBOSOMAL PROTEIN L10-L12(NTD) COMPLEX, SPACE GROUP P212121, FORM B
Descriptor:50S ribosomal protein L10, 50S ribosomal protein L7/L12
Authors:Diaconu, M., Kothe, U., Schluenzen, F., Fischer, N., Harms, J.M., Tonevitski, A.G., Stark, H., Rodnina, M.V., Wahl, M.C.
Deposit date:2005-04-07
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation.
Cell(Cambridge,Mass.), 121, 2005
2AEU
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MJ0158, APO FORM
Descriptor:Hypothetical protein MJ0158, SULFATE ION
Authors:Kaiser, J.T., Gromadski, K., Rother, M., Engelhardt, H., Rodnina, M.V., Wahl, M.C.
Deposit date:2005-07-24
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional investigation of a putative archaeal selenocysteine synthase
Biochemistry, 44, 2005
2AEV
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MJ0158, NABH4-REDUCED FORM
Descriptor:Hypothetical protein MJ0158, SULFATE ION
Authors:Kaiser, J.T., Gromadski, K., Rother, M., Engelhardt, H., Rodnina, M.V., Wahl, M.C.
Deposit date:2005-07-24
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional investigation of a putative archaeal selenocysteine synthase
Biochemistry, 44, 2005
3L0U
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THE CRYSTAL STRUCTURE OF UNMODIFIED TRNAPHE FROM ESCHERICHIA COLI
Descriptor:Unmodified tRNAPhe, MAGNESIUM ION, POTASSIUM ION
Authors:Byrne, R.T., Konevega, A.L., Rodnina, M.V., Antson, A.A.
Deposit date:2009-12-10
Release date:2010-03-16
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of unmodified tRNAPhe from Escherichia coli
Nucleic Acids Res., 38, 2010
4V6Y
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN CLASSIC PRE-TRANSLOCATION STATE (PRE1A)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V6Z
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN CLASSIC PRE-TRANSLOCATION STATE (PRE1B)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V70
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE PRE-TRANSLOCATION STATE (PRE3)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V71
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE PRE-TRANSLOCATION STATE (PRE2)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V72
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN HYBRID PRE-TRANSLOCATION STATE (PRE4)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V73
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN HYBRID PRE-TRANSLOCATION STATE (PRE5A)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V74
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70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN HYBRID PRE-TRANSLOCATION STATE (PRE5B)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V75
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN CLASSIC POST-TRANSLOCATION STATE (POST1)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V76
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE POST-TRANSLOCATION STATE (POST2A)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V77
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE POST-TRANSLOCATION STATE (POST2B)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V78
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE POST-TRANSLOCATION STATE (POST3A)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V79
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E. COLI 70S-FMETVAL-TRNAVAL-TRNAFMET COMPLEX IN INTERMEDIATE POST-TRANSLOCATION STATE (POST3B)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V7A
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E. COLI 70S-FMETVAL-TRNAVAL POST-TRANSLOCATION COMPLEX (POST4)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Blau, C., Bock, L.V., Schroder, G.F., Davydov, I., Fischer, N., Stark, H., Rodnina, M.V., Vaiana, A.C., Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4YCO
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E. COLI DIHYDROURIDINE SYNTHASE C (DUSC) IN COMPLEX WITH TRNAPHE
Descriptor:tRNA-dihydrouridine synthase C, tRNAphe, FLAVIN MONONUCLEOTIDE, ...
Authors:Byrne, R.T., Jenkins, H.T., Peters, D.T., Whelan, F., Stowell, J., Aziz, N., Kasatsky, P., Rodnina, M.V., Koonin, E.V., Konevega, A.L., Antson, A.A.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YCP
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E. COLI DIHYDROURIDINE SYNTHASE C (DUSC) IN COMPLEX WITH TRNATRP
Descriptor:tRNA-dihydrouridine synthase C, tRNATrp, FLAVIN MONONUCLEOTIDE, ...
Authors:Byrne, R.T., Jenkins, H.T., Peters, D.T., Whelan, F., Stowell, J., Aziz, N., Kasatsky, P., Rodnina, M.V., Koonin, E.V., Konevega, A.L., Antson, A.A.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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